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BMC Psychiatry
Published in: BMC Psychiatry 1/2014

Open Access 01-12-2014 | Research article

Exploring health-related quality of life in eating disorders by a cross-sectional study and a comprehensive review

Authors: Monica Baiano, Pierandrea Salvo, Pierluigi Righetti, Lucia Cereser, Erika Baldissera, Ilenia Camponogara, Matteo Balestrieri

Published in: BMC Psychiatry | Issue 1/2014

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Abstract

Background

People with eating disorders (ED) often report poor health-related quality of life (HRQoL), which is explicitly correlated to illness’ severity and its effects on cognitive performance. We aimed to analyze health-related quality of life (HRQoL) in subgroups of eating disorder (ED) patients by using the brief version of WHOQoL questionnaire (WHOQoL-BREF) before treatment administration. Moreover, in order to compare our findings with other published data, we carried out a comprehensive review of the literature on HRQoL in ED patients.

Methods

Our review was carried out by means of an accurate data mining of PsychInfo and Medline databases and other available sources. In our cross-sectional study, eighty female ED patients (26 with bulimia nervosa, 33 with anorexia nervosa, 7 with binge eating disorder and 14 with ED not otherwise specified) completed the WHOQoL-BREF. HRQoL scores were compared among ED subgroups and clinical information (presence of previous contacts, length of illness, psychiatric comorbidity) was considered in the analysis.

Results

Our review shows that with few exceptions ED patients have a poorer HRQoL than the healthy population of control and sometimes the mental component of HRQoL is the most involved dimension. Moreover, there are no differences in the HRQoL among ED groups, even if AN patients in some studies have a lower HRQoL scores. Furthermore, BED patients have a poorer HRQoL than obese patients who do not have binge episodes. Finally, all treatments were positively correlated with an improvement on general and specific QoL dimensions. In our sample, ED subgroups differed only for Psychological Health HRQoL scores (F = 4.072, df = 3; p = 0.01). No differences were found between inpatients and outpatients, treatment naïve and previously treated patients and patients with or without psychiatric comorbidity. Moreover, HRQoL scores were not correlated to length of illness within each ED subgroup.

Conclusions

The analysis of the literature adds some relevant information on HRQoL in ED and may address the future research toward the exploration of specific questions. One of these may be the prominent role of Psychological Health domain in HRQoL, since our study confirms that this component is able to differentiate eating disorders.
Literature
1.
The WHOQOL Group: Development of the World Health Organization WHOQOL-BREF Quality of Life assessment. Psychol Med. 1998, 28: 551-558.CrossRef
2.
Centers for Disease Control and Prevention: Measuring healthy days: Population assessment of health-related quality of life. 2000, Atlanta, Georgia: CDCP
3.
Engel SG, Adair CE, Las Hayas C, Abraham S: Health related quality of life and eating disorders: a review and an update. Int J Eat Disord. 2009, 42: 179-187. 10.1002/eat.20602.CrossRefPubMed
4.
Boini S, Briançon S, Guillemin F, Galan P, Hercberg S: Impact of cancer occurrence on health-related quality of life: a longitudinal pre-post assessment. Health Qual Life Outcomes. 2004, 2: 4-10.1186/1477-7525-2-4.CrossRefPubMedPubMedCentral
5.
Bullinger M: Health-related quality of life and subjective health. Psychother Psychosom Med Psychol. 1997, 47: 76-91.PubMed
6.
Guyatt GH, Feeny D, Patrick DL: Measuring health-related quality of life. Ann Intern Med. 1993, 118: 622-629. 10.7326/0003-4819-118-8-199304150-00009.CrossRefPubMed
7.
De la Rie S, Noordenbos G, Donker M, van Furth E: Quality of life and eating disorders. Qual Life Res. 2005, 14: 1511-1522. 10.1007/s11136-005-0585-0.CrossRefPubMed
8.
Bosanac P, Kurlender S, Stojanovska L, Hallam K, Norman T, McGrath C, Burrows G, Wesnes K, Manktelow T, Olver J: Neuropsychological study of underweight and “weight-recovered” anorexia nervosa compared with bulimia nervosa and normal controls. Int J Eat Disord. 2007, 40: 613-621. 10.1002/eat.20412.CrossRefPubMed
9.
Fowler L, Blackwell A, Jaffa A, Palmer R, Robbins TW, Sahakian BJ, Dowson JH: Profile of neurocognitive impairments associated with female in-patients with anorexia nervosa. Psychol Med. 2006, 36: 517-527.CrossRefPubMed
10.
Padierna A, Quintana JM, Arostegui I, Gonzalez N, Horcajo MJ: The health-related quality of life in eating disorders. Qual Life Res. 2000, 9: 667-674. 10.1023/A:1008973106611.CrossRefPubMed
11.
Mond JM, Hay PJ, Rodgers B, Owen C, Beumont PJV: Assessing quality of life in eating disorder patients. Qual Life Res. 2005, 14: 171-178. 10.1007/s11136-004-2657-y.CrossRefPubMed
12.
Davies M, Brody D, deGruy FV, Spitzer RL, Kroenke K, Linzer M, Hahn SR, Williams JB: Health-related quality of life in primary care patients with mental disorders. Results from the PRIME-MD 1000 Study. JAMA. 1995, 274: 1511-1517. 10.1001/jama.1995.03530190025030.CrossRefPubMed
13.
Bohn K, Doll HA, Cooper Z, O’Connor M, Palmer RL, Fairburn CG: The measurement of impairment due to eating psychopathology. Behav Res Ther. 2008, 46: 1105-1110. 10.1016/j.brat.2008.06.012.CrossRefPubMedPubMedCentral
14.
Passarelli Tirico P, Stefano SC, Blay SL: Quality of life and eating disorders: a systematic review. Cad Saude Publica. 2010, 26: 431-449. 10.1590/S0102-311X2010000300002.CrossRef
15.
Jenkins PE, Hoste RR, Meyer C, Blissett JM: Eating disorders and quality of life: a review of the literature. Clin Psychol Rev. 2011, 31: 113-121. 10.1016/j.cpr.2010.08.003.CrossRefPubMed
16.
SPSS Inc: SPSS for Windows, Version 16.0. 2007, Chicago: SPSS Inc
17.
StataCorp: Stata Statistical Software: Release 10. 2007, College Station, TX: StataCorp LP
18.
Hay P: Quality of life and bulimic eating disorder behaviours: findings from a community-based sample. Int J Eat Disord. 2003, 33: 434-442. 10.1002/eat.10162.CrossRefPubMed
19.
Doll HA, Petersen SE, Stewart-Brown SL: Eating disorders and emotional and physical well-being: associations between student self-reports of eating disorders and quality of life as measured by the SF-36. Qual Life Res. 2005, 14: 705-717. 10.1007/s11136-004-0792-0.CrossRefPubMed
20.
Herpetz-Dahlmann B, Wille N, Hölling H, Vloet TD, Ravens-Sieberer U, BELLA study group: Disordered eating behaviour and attitudes, associated psychopathology and health-related quality of life: results of the BELLA study. Eur Child Adolesc Psychiatry. 2008, 17: 82-91.CrossRef
21.
Vallance JK, Latner JD, Gleaves DH: The relationship between eating disorder psychopathology and health-related quality of life within a community sample. Qual Life Res. 2011, 20: 675-682. 10.1007/s11136-010-9799-x.CrossRefPubMed
22.
Mond J, Hay P, Rodgers B, Owen C: Quality of life impairment in a community sample of women with eating disorders. Aust N Z J Psychiatry. 2012, 46: 561-568. 10.1177/0004867411433967.CrossRefPubMed
23.
Mitchison D, Hay P, Mond J, Slewa-Younan S: Self-reported history of anorexia nervosa and current quality of life: findings from a community-based study. Qual Life Res. 2013, 22: 273-281. 10.1007/s11136-012-0157-z.CrossRefPubMed
24.
Keilen M, Treasure T, Schmidt U, Treasure J: Quality of life measurements in eating disorders, angina, and transplant candidates: are they comparable?. J R Soc Med. 1994, 87: 441-444.PubMedPubMedCentral
25.
González-Pinto A, Inmaculada F, Cristina R, de Corres BF, Sonsoles E, Fernando R, Purificacion L: Purging behaviors and comorbidity as predictive factors of quality of life in anorexia nervosa. Int J Eat Disord. 2004, 36: 445-450. 10.1002/eat.20058.CrossRefPubMed
26.
Engel SG, Wittrock DA, Crosby RD, Wonderlich SA, Mitchell JE, Kolotkin RL: Development and psychometric validation of an eating disorder-specific health-related quality of life instrument. Int J Eat Disord. 2006, 39: 62-71. 10.1002/eat.20200.CrossRefPubMed
27.
De la Rie S, Noordenbos G, Donker M, van Furth E: The patient’s view on quality of life and eating disorders. Int J Eat Disord. 2007, 40: 13-20. 10.1002/eat.20338.CrossRefPubMed
28.
Latner JD, Vallance JK, Buckett G: Health-related quality of life in women with eating disorders: association with subjective and objective binge eating. J Clin Psychol Med Settings. 2008, 15: 148-153. 10.1007/s10880-008-9111-1.CrossRefPubMed
29.
Bamford B, Sly R: Exploring quality of life in the eating disorders. Eur Eat Disord Rev. 2010, 18: 147-153. 10.1002/erv.975.CrossRefPubMed
30.
Hsu LK, Mulliken B, McDonagh B, Krupa Das S, Rand W, Fairburn CG, Rolls B, McCrory MA, Saltzman E, Shikora S, Dwyer J, Roberts S: Binge eating disorder in extreme obesity. Int J Obes Relat Metab Disord. 2002, 26: 1398-1403. 10.1038/sj.ijo.0802081.CrossRefPubMed
31.
de Zwaan M, Lancaster KL, Mitchell JE, Howell LM, Monson N, Roerig JL, Crosby RD: Health-related quality of life in morbidly obese patients: effect of gastric bypass surgery. Obes Surg. 2002, 12: 773-780. 10.1381/096089202320995547.CrossRefPubMed
32.
Masheb RM, Grilo CM: Quality of life in patients with binge eating disorder. Eat Weight Disord. 2004, 9: 194-199. 10.1007/BF03325066.CrossRefPubMed
33.
Kolotkin RL, Westman EC, Østbye T, Crosby RD, Eisenson HJ, Binks M: Does binge eating disorder impact weight-related quality of life?. Obes Res. 2004, 12: 999-1005. 10.1038/oby.2004.122.CrossRefPubMed
34.
Rieger E, Wilfley DE, Stein RI, Marino V, Crow SJ: A comparison of quality of life in obese individuals with and without binge eating disorder. Int J Eat Disord. 2005, 37: 234-240. 10.1002/eat.20101.CrossRefPubMed
35.
Colles SL, Dixon JB, O’Brien PE: Loss of control is central to psychological disturbance associated with binge eating disorder. Obesity (Silver Spring). 2008, 16: 608-614. 10.1038/oby.2007.99.CrossRef
36.
Folope V, Chapelle C, Grigioni S, Coëffier M, Déchelotte P: Impact of eating disorders and psychological distress on the quality of life of obese people. Nutrition. 2012, 28: e7-e13. 10.1016/j.nut.2011.12.005.CrossRefPubMed
37.
Ranzenhofer LM, Columbo KM, Tanofsky-Kraff M, Shomaker LB, Cassidy O, Matheson BE, Kolotkin RL, Checchi JM, Keil M, McDuffie JR, Yanovski JA: Binge eating and weight-related quality of life in obese adolescents. Nutrients. 2012, 4: 167-180. 10.3390/nu4030167.CrossRefPubMedPubMedCentral
38.
Wade TD, Wilksch SM, Lee C: A longitudinal investigation of the impact of disordered eating on young women’s quality of life. Health Psychol. 2012, 31: 352-359.CrossRefPubMed
39.
Padierna A, Quintana JM, Arostegui I, Gonzalez N, Horcajo MJ: Changes in health related quality of life among patients treated for eating disorders. Qual Life Res. 2002, 11: 545-552. 10.1023/A:1016324527729.CrossRefPubMed
40.
Muñoz P, Quintana JM, Las Hayas C, Aguirre U, Padierna A, González-Torres MA: Assessment of the impact of eating disorders on quality of life using the disease-specific, health-related quality of life for eating disorders (HeRQoLED) questionnaire. Qual Life Res. 2009, 18: 1137-1146. 10.1007/s11136-009-9542-7.CrossRefPubMed
41.
Adair CE, Marcoux GC, Bischoff TF, Cram BS, Ewashen CJ, Pinzon J, Gusella JL, Geller J, Scattolon Y, Fergusson P, Styles L, Brown KE: Responsiveness of the eating disorders quality of life scale (EDQLS) in a longitudinal multi-site sample. Health Qual Life Outcomes. 2010, 8: 83-10.1186/1477-7525-8-83.CrossRefPubMedPubMedCentral
42.
Marchesini G, Natale S, Chierici S, Manini R, Besteghi L, Di Domizio S, Sartini A, Pasqui F, Baraldi L, Forlani G, Melchionda N: Effects of cognitive-behavioural therapy on health-related quality of life in obese subjects with and without binge eating disorder. Int J Obes Relat Metab Disord. 2002, 26: 1261-1267. 10.1038/sj.ijo.0802073.CrossRefPubMed
43.
Nickel C, Tritt K, Muehlbacher M, Pedrosa Gil F, Mitterlehner FO, Kaplan P, Lahmann C, Leiberich PK, Krawczyk J, Kettler C, Rother WK, Loew TH, Nickel MK: Topiramate treatment in bulimia nervosa patients: a randomized, double-blind, placebo-controlled trial. Int J Eat Disord. 2005, 38: 295-300. 10.1002/eat.20202.CrossRefPubMed
44.
Wilfley DE, Crow SJ, Hudson JI, Mitchell JE, Berkowitz RI, Blakesley V, Walsh BT, Sibutramine Binge Eating Disorder Research Group: Efficacy of sibutramine for the treatment of binge eating disorder: a randomized multicenter placebo-controlled double-blind study. Am J Psychiatry. 2008, 165: 51-58.CrossRefPubMed
45.
Abraham SF, Brown T, Boyd C, Luscombe G, Russel J: Quality of life: eating disorders. Aust New Zeal J Psychiatr. 2006, 40: 150-155. 10.1080/j.1440-1614.2006.01762.x.CrossRef
46.
McHugh MD: Readiness for change and short-term outcomes of female adolescents in residential treatment for anorexia nervosa. Int J Eat Disord. 2007, 40: 602-612. 10.1002/eat.20425.CrossRefPubMed
47.
Green AE, Dymek-Valentine M, Pytluk S, Le Grange D, Alverdy J: Psychosocial outcome of gastric bypass surgery for patients with and without binge eating. Obes Surg. 2004, 14: 975-985. 10.1381/0960892041719590.CrossRefPubMed
48.
Karwautz A, de Zwaan M, Wöber-Bingöl C, Wöber C, Friedrich MH: Awareness of early-onset anorexia nervosa. Eat Weight Disord. 1997, 2: 138-143. 10.1007/BF03339964.CrossRefPubMed
49.
Spindler A, Milos G: Links between eating disorder symptom severity and psychiatric comorbidity. Eat Behav. 2007, 8: 364-373. 10.1016/j.eatbeh.2006.11.012.CrossRefPubMed
50.
Sihvola E, Keski-Rahkonen A, Dick DM, Hoek HW, Raevuori A, Rose RJ, Pulkkinen L, Marttunen M, Kaprio J: Prospective associations of early-onset Axis I disorders with developing eating disorders. Compr Psychiatry. 2009, 50: 20-25. 10.1016/j.comppsych.2008.05.004.CrossRefPubMed
51.
Woodside BD, Staab R: Management of psychiatric comorbidity in anorexia nervosa and bulimia nervosa. CNS Drugs. 2006, 20: 665-663. 10.2165/00023210-200620080-00005.CrossRef
52.
Blinder BJ, Cumella EJ, Sanathara VA: Psychiatric comorbidities of female inpatients with eating disorders. Psychosom Med. 2006, 68: 454-462. 10.1097/01.psy.0000221254.77675.f5.CrossRefPubMed
53.
Hjern A, Lindberg L, Lindblad F: Outcome and prognostic factors for adolescent female in-patients with anorexia nervosa: 9-to14-year follow-up. Br J Psychiatry. 2006, 18: 428-432.CrossRef
54.
Steinhausen HC: The outcome of anorexia nervosa in the 20th century. Am J Psychiatry. 2002, 59: 1284-1293.CrossRef
55.
Patrick L: Eating Disorders: a review of the literature with emphasis on medical complications and clinical nutrition. Altern Med Rev. 2002, 7: 184-202.PubMed
56.
Gilboa-Schechtman E, Avnon L, Zubery E, Jeczmien P: Emotional processing in eating disorders: specific impairment or general distress related deficiency?. Depress Anxiety. 2006, 23: 331-339. 10.1002/da.20163.CrossRefPubMed
57.
Pollatos O, Kurz AL, Albrecht J, Schreder T, Kleemann AM, Schöpf V, Kopietz R, Wiesmann M, Schandry R: Reduced perception of bodily signals in anorexia nervosa. Eat Behav. 2008, 9: 381-388. 10.1016/j.eatbeh.2008.02.001.CrossRefPubMed
58.
Hudson JI, Hiripi E, Pope HG, Kessler RC: The prevalence and correlates of eating disorders in the National Comorbidity Survey Replication. Biol Psychiatry. 2007, 61: 348-358. 10.1016/j.biopsych.2006.03.040.CrossRefPubMed
59.
Reba-Harrelson L, Von Holle A, Hamer RM, Swann R, Reyes ML, Bulik CM: Patterns and prevalence of disordered eating and weight control behaviors in women ages 25–45. Eat Weight Disord. 2009, 14: 190-198. 10.1007/BF03325116.CrossRef
60.
Bulik CM, Sullivan PF, Kendler KS: Medical and psychiatric morbidity in obese women with and without binge eating. Int J Eat Disord. 2002, 32: 72-78. 10.1002/eat.10072.CrossRefPubMed
61.
Whiteside U, Chen E, Neighbors C, Hunter D, Lo T, Larimer M: Difficulties regulating emotions: do binge eaters have fewer strategies to modulate and tolerate negative affect?. Eat Behav. 2007, 8: 162-169. 10.1016/j.eatbeh.2006.04.001.CrossRefPubMed
62.
Peterson CB, Miller KB, Crow SJ, Thuras P, Mitchell JE: Subtypes of binge eating disorder based on psychiatric history. Int J Eat Disord. 2005, 38: 273-276. 10.1002/eat.20174.CrossRefPubMed
63.
Peterson CB, Thuras P, Ackard DM, Mitchell JE, Berg K, Sandager N, Wonderlich SA, Pederson MW, Crow SJ: Personality dimensions in bulimia nervosa, binge eating disorder, and obesity. Compr Psychiatry. 2010, 51: 31-36. 10.1016/j.comppsych.2009.03.003.CrossRefPubMed
Metadata
Title
Exploring health-related quality of life in eating disorders by a cross-sectional study and a comprehensive review
Authors
Monica Baiano
Pierandrea Salvo
Pierluigi Righetti
Lucia Cereser
Erika Baldissera
Ilenia Camponogara
Matteo Balestrieri
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2014
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/1471-244X-14-165

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