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Published in: International Urogynecology Journal 5/2009

01-05-2009 | Original Article

Experimental biomechanical evaluation of polypropylene prostheses used in pelvic organ prolapse surgery

Authors: Fabrice Sergent, Nicolas Desilles, Yann Lacoume, Claude Bunel, Jean-Paul Marie, Loïc Marpeau

Published in: International Urogynecology Journal | Issue 5/2009

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Abstract

Introduction and hypothesis

Although polypropylene (PP) is the most common biomaterial used to repair genital prolapse via vaginal route, its mechanical properties however remain obscure.

Methods

An abdominal hernia rabbit model was used to evaluate retraction, solidity, and elasticity of the principal types of PP prostheses currently available, i.e., three large pore size monofilament prostheses, one heavy weight (HWPP), a second low weight (LWPP), and a third coated with atelocollagen (CPP). A small pore size multifilament PP (MPP) implant was also tested.

Results

In comparison with HWPP (12%), LWPP (15%), and MPP (30%), CPP had less retraction (8% of the original size). Unlike pore size, weight prosthesis is not an influencing factor for retraction. Atelocollagen coating reduced retraction. HWPP and MPP were the most solid prostheses. MPP supported the greatest elastic force.

Conclusions

When the biomechanical parameters were comparatively assessed, HWPP was considered to have the most advantageous properties for prolapse surgery.
Literature
1.
go back to reference Abdel-Fattah M, Ramsay I; West of Scotland Study Group (2008) Retrospective multicentre study of the new minimally invasive mesh repair devices for pelvic organ prolapse. BJOG 115:22–30CrossRef Abdel-Fattah M, Ramsay I; West of Scotland Study Group (2008) Retrospective multicentre study of the new minimally invasive mesh repair devices for pelvic organ prolapse. BJOG 115:22–30CrossRef
2.
go back to reference Nygaard IE, McCreery R, Brubaker L, Connolly A, Cundiff G, Weber AM et al (2004) Pelvic floor disorders network. Abdominal sacrocolpopexy: a comprehensive review. Obstet Gynecol 104:805–823PubMed Nygaard IE, McCreery R, Brubaker L, Connolly A, Cundiff G, Weber AM et al (2004) Pelvic floor disorders network. Abdominal sacrocolpopexy: a comprehensive review. Obstet Gynecol 104:805–823PubMed
3.
go back to reference Higgs P, Goh J, Krause H, Sloane K, Carey M (2005) Abdominal sacral colpopexy: an independent prospective long-term follow-up study. Aust N Z J Obstet Gynaecol 45:430–434PubMedCrossRef Higgs P, Goh J, Krause H, Sloane K, Carey M (2005) Abdominal sacral colpopexy: an independent prospective long-term follow-up study. Aust N Z J Obstet Gynaecol 45:430–434PubMedCrossRef
4.
go back to reference Maher C, Baessler K, Glazener CM, Adams EJ, Hagen S (2004) Surgical management of pelvic organ prolapse in women. Cochrane Database Syst Rev 4:CD004014PubMed Maher C, Baessler K, Glazener CM, Adams EJ, Hagen S (2004) Surgical management of pelvic organ prolapse in women. Cochrane Database Syst Rev 4:CD004014PubMed
5.
go back to reference Sergent F, Sentilhes L, Resch B, Diguet A, Verspyck E, Marpeau L (2007) Prosthetic repair of genito-urinary prolapses by the transobturateur infracoccygeal hammock technique: medium-term results. J Gynecol Obstet Biol Reprod 36:459–467 Sergent F, Sentilhes L, Resch B, Diguet A, Verspyck E, Marpeau L (2007) Prosthetic repair of genito-urinary prolapses by the transobturateur infracoccygeal hammock technique: medium-term results. J Gynecol Obstet Biol Reprod 36:459–467
6.
go back to reference Mathé ML, Lavigne JP, Oliva-Lauraire MC, Guiraud I, Marès P, de Tayrac R (2007) Comparison of different biomaterials for vaginal surgery using an in vivo model of meshes infection in rats. Gynecol Obstet Fertil 35:398–405PubMedCrossRef Mathé ML, Lavigne JP, Oliva-Lauraire MC, Guiraud I, Marès P, de Tayrac R (2007) Comparison of different biomaterials for vaginal surgery using an in vivo model of meshes infection in rats. Gynecol Obstet Fertil 35:398–405PubMedCrossRef
7.
go back to reference Deffieux X, de Tayrac R, Huel C, Bottero J, Gervaise A, Bonnet K et al (2007) Vaginal mesh erosion after transvaginal repair of cystocele using Gynemesh or Gynemesh-Soft in 138 women: a comparative study. Int Urogynecol J Pelvic Floor Dysfunct 18:73–79PubMedCrossRef Deffieux X, de Tayrac R, Huel C, Bottero J, Gervaise A, Bonnet K et al (2007) Vaginal mesh erosion after transvaginal repair of cystocele using Gynemesh or Gynemesh-Soft in 138 women: a comparative study. Int Urogynecol J Pelvic Floor Dysfunct 18:73–79PubMedCrossRef
8.
go back to reference Amid PK (1997) Classification of biomaterials and their related complication in abdominal wall hernia surgery. Hernia 1:15–21CrossRef Amid PK (1997) Classification of biomaterials and their related complication in abdominal wall hernia surgery. Hernia 1:15–21CrossRef
9.
go back to reference Alponat A, Lakshminarasappa SR, Yavuz N, Goh PMY (1997) Prevention of adhesions by Seprefilm, an absorbable adhesion barrier: an incisional hernia model in rats. Am Surg 63:818–819PubMed Alponat A, Lakshminarasappa SR, Yavuz N, Goh PMY (1997) Prevention of adhesions by Seprefilm, an absorbable adhesion barrier: an incisional hernia model in rats. Am Surg 63:818–819PubMed
10.
go back to reference Claerhout F, Deprest J, Zheng F, Konstantinovic M, Lagae P, De Ridder D (2003) Long term evaluation of the tissue response and mechanical properties of two collagen based and polypropylene implants in a rabbit model for abdominal wall repair. Neurourol Urodyn 5:516–517 Claerhout F, Deprest J, Zheng F, Konstantinovic M, Lagae P, De Ridder D (2003) Long term evaluation of the tissue response and mechanical properties of two collagen based and polypropylene implants in a rabbit model for abdominal wall repair. Neurourol Urodyn 5:516–517
11.
go back to reference Klinge U, Klosterhalfen B, Müller M, Ottinger AP, Schumpelick V (1998) Shrinking of polypropylene mesh in vivo: an experimental study in dogs. Eur J Surg 164:965–969PubMedCrossRef Klinge U, Klosterhalfen B, Müller M, Ottinger AP, Schumpelick V (1998) Shrinking of polypropylene mesh in vivo: an experimental study in dogs. Eur J Surg 164:965–969PubMedCrossRef
12.
go back to reference Scheidbach H, Tamme C, Tannapfel A, Lippert H, Köckerling F (2004) In vivo studies comparing the biocompatibility of various polypropylene meshes and their handling properties during endoscopic total extraperitoneal (TEP) patchplasty: an experimental study in pigs. Surg Endosc 18:211–220PubMedCrossRef Scheidbach H, Tamme C, Tannapfel A, Lippert H, Köckerling F (2004) In vivo studies comparing the biocompatibility of various polypropylene meshes and their handling properties during endoscopic total extraperitoneal (TEP) patchplasty: an experimental study in pigs. Surg Endosc 18:211–220PubMedCrossRef
13.
go back to reference Cobb WS, Burns JM, Peindl RD, Carbonell AM, Matthews BD, Kercher KW et al (2006) Textile analysis of heavy weight, mid-weight, and light weight polypropylene mesh in a porcine ventral hernia model. J Surg Res 136:1–7PubMedCrossRef Cobb WS, Burns JM, Peindl RD, Carbonell AM, Matthews BD, Kercher KW et al (2006) Textile analysis of heavy weight, mid-weight, and light weight polypropylene mesh in a porcine ventral hernia model. J Surg Res 136:1–7PubMedCrossRef
14.
go back to reference Klinge U, Klosterhalfen B, Birkenhauer V, Junge K, Conze J, Schumpelick V (2002) Impact of polymer pore size on the interface scar formation in a rat model. J Surg Res 103:208–214PubMedCrossRef Klinge U, Klosterhalfen B, Birkenhauer V, Junge K, Conze J, Schumpelick V (2002) Impact of polymer pore size on the interface scar formation in a rat model. J Surg Res 103:208–214PubMedCrossRef
15.
go back to reference Weyhe D, Schmitz I, Belyaev O, Grabs R, Müller KM, Uhl W et al (2006) Experimental comparison of monofile light and heavy polypropylene meshes: less weight does not mean less biological response. World J Surg 30:1586–1591PubMedCrossRef Weyhe D, Schmitz I, Belyaev O, Grabs R, Müller KM, Uhl W et al (2006) Experimental comparison of monofile light and heavy polypropylene meshes: less weight does not mean less biological response. World J Surg 30:1586–1591PubMedCrossRef
16.
go back to reference Arnaud JP, Hennekinne-Mucci S, Pessaux P, Tuech JJ, Aube C (2003) Ultrasound detection of visceral adhesion after intraperitoneal ventral hernia treatment: a comparative study of protected versus unprotected meshes. Hernia 7:85–88PubMedCrossRef Arnaud JP, Hennekinne-Mucci S, Pessaux P, Tuech JJ, Aube C (2003) Ultrasound detection of visceral adhesion after intraperitoneal ventral hernia treatment: a comparative study of protected versus unprotected meshes. Hernia 7:85–88PubMedCrossRef
17.
go back to reference de Tayrac R, Devoldere G, Renaudie J, Villard P, Guilbaud O, Eglin G, The French Ugytex Study Group (2007) Prolapse repair by vaginal route using a new protected low-weight polypropylene mesh: 1-year functional and anatomical outcome in a prospective multicentre study. Int Urogynecol J Pelvic Floor Dysfunct 18:251–256PubMedCrossRef de Tayrac R, Devoldere G, Renaudie J, Villard P, Guilbaud O, Eglin G, The French Ugytex Study Group (2007) Prolapse repair by vaginal route using a new protected low-weight polypropylene mesh: 1-year functional and anatomical outcome in a prospective multicentre study. Int Urogynecol J Pelvic Floor Dysfunct 18:251–256PubMedCrossRef
18.
go back to reference Konstantinovic ML, Pille E, Malinowska M, Verbeken E, De Ridder D, Deprest J (2007) Tensile strength and host response towards different polypropylene implant materials used for augmentation of fascial repair in a rat model. Int Urogynecol J Pelvic Floor Dysfunct 18:619–626PubMedCrossRef Konstantinovic ML, Pille E, Malinowska M, Verbeken E, De Ridder D, Deprest J (2007) Tensile strength and host response towards different polypropylene implant materials used for augmentation of fascial repair in a rat model. Int Urogynecol J Pelvic Floor Dysfunct 18:619–626PubMedCrossRef
19.
go back to reference Debodinance P, Berrocal J, Clavé H, Cosson M, Garbin O, Jacquetin B et al (2004) Changing attitudes on the surgical treatment of urogenital prolapse: birth of the tension-free vaginal mesh. J Gynecol Obstet Biol Reprod 33:577–588 Debodinance P, Berrocal J, Clavé H, Cosson M, Garbin O, Jacquetin B et al (2004) Changing attitudes on the surgical treatment of urogenital prolapse: birth of the tension-free vaginal mesh. J Gynecol Obstet Biol Reprod 33:577–588
20.
go back to reference Klosterhalfen B, Klinge U, Schumpelick V (1998) Functional and morphological evaluation of different polypropylene-mesh modifications for abdominal wall repair. Biomaterials 19:2235–2246PubMedCrossRef Klosterhalfen B, Klinge U, Schumpelick V (1998) Functional and morphological evaluation of different polypropylene-mesh modifications for abdominal wall repair. Biomaterials 19:2235–2246PubMedCrossRef
21.
go back to reference Cobb WS, Burns JM, Kercher KW, Matthews BD, James Norton H, Todd Heniford B (2005) Normal intraabdominal pressure in healthy adults. J Surg Res 129:231–235PubMedCrossRef Cobb WS, Burns JM, Kercher KW, Matthews BD, James Norton H, Todd Heniford B (2005) Normal intraabdominal pressure in healthy adults. J Surg Res 129:231–235PubMedCrossRef
22.
go back to reference O’Dwyer PJ, Kingsnorth AN, Molloy RG, Small PK, Lammers B, Horeyseck G (2005) Randomized clinical trial assessing impact of a lightweight or heavyweight mesh on chronic pain after inguinal hernia repair. Br J Surg 92:166–170PubMedCrossRef O’Dwyer PJ, Kingsnorth AN, Molloy RG, Small PK, Lammers B, Horeyseck G (2005) Randomized clinical trial assessing impact of a lightweight or heavyweight mesh on chronic pain after inguinal hernia repair. Br J Surg 92:166–170PubMedCrossRef
23.
go back to reference Altman D, Zetterstrom J, Mellgren A, Gustafsson C, Anzen B, Lopez A (2006) A three-year prospective assessment of rectocele repair using porcine xenograft. Obstet Gynecol 107:59–65PubMed Altman D, Zetterstrom J, Mellgren A, Gustafsson C, Anzen B, Lopez A (2006) A three-year prospective assessment of rectocele repair using porcine xenograft. Obstet Gynecol 107:59–65PubMed
24.
go back to reference Wheeler TL 2nd, Richter HE, Duke AG, Burgio KL, Redden DT, Varner RE (2006) Outcomes with porcine graft placement in the anterior vaginal compartment in patients who undergo high vaginal uterosacral suspension and cystocele repair. Am J Obstet Gynecol 194:1486–1491PubMedCrossRef Wheeler TL 2nd, Richter HE, Duke AG, Burgio KL, Redden DT, Varner RE (2006) Outcomes with porcine graft placement in the anterior vaginal compartment in patients who undergo high vaginal uterosacral suspension and cystocele repair. Am J Obstet Gynecol 194:1486–1491PubMedCrossRef
25.
go back to reference Pariente JL, Villars F, Bram R, Ibarboure E (2005) Mechanical evaluation of various suburethral tapes used for the treatment of stress urinary incontinence. Prog Urol 15:1106–1109PubMed Pariente JL, Villars F, Bram R, Ibarboure E (2005) Mechanical evaluation of various suburethral tapes used for the treatment of stress urinary incontinence. Prog Urol 15:1106–1109PubMed
Metadata
Title
Experimental biomechanical evaluation of polypropylene prostheses used in pelvic organ prolapse surgery
Authors
Fabrice Sergent
Nicolas Desilles
Yann Lacoume
Claude Bunel
Jean-Paul Marie
Loïc Marpeau
Publication date
01-05-2009
Publisher
Springer-Verlag
Published in
International Urogynecology Journal / Issue 5/2009
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-009-0825-x

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