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Critical Care
Published in: Critical Care 3/2013

01-06-2013 | Commentary

Expect the unexpected: clinical trials are key to understanding post-intensive care syndrome

Authors: Michael F O'Connor, Mark E Nunnally

Published in: Critical Care | Issue 3/2013

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Abstract

Long-term follow-up of randomized prospective trials of treatments in the intensive care unit may allow us to attain some understanding of the causes of post-intensive care syndrome. This in turn may allow us to produce better long-term outcomes among survivors of critical illness.
Literature
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Wittbrodt P, Haase N, Butowska D, Winding R, Poulsen JB, Perner A, the 6S trial group and the Scandinavian Critical Care Trials Group: Quality of life and pruritus in patients with severe sepsis resuscitated with hydroxyethyl starch. Long-term follow-up of a randomised trial. Crit Care 2013, 17: R58. 10.1186/cc12586PubMedCentralCrossRefPubMed
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Needham DM, Davidson J, Cohen H, Hopkins RO, Weinert C, Wunsch H, Zawistowski C, Bemis-Dougherty A, Berney SC, Bienvenu OJ, Brady SL, Brodsky MB, Denehy L, Elliott D, Flatley C, Harabin AL, Jones C, Louis D, Meltzer W, Muldoon SR, Palmer JB, Perme C, Robinson M, Schmidt DM, Scruth E, Spill GR, Storey CP, Render M, Votto J, Harvey MA: Improving long-term outcomes after discharge from intensive care unit: report from a stakeholders' conference. Crit Care Med 2012, 40: 502-509. 10.1097/CCM.0b013e318232da75CrossRefPubMed
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Coopersmith CM, Wunsch H, Fink MP, Linde-Zwirble WT, Olsen KM, Sommers MS, Anand KJ, Tchorz KM, Angus DC, Deutschman CS: A comparison of critical care research funding and the financial burden of critical illness in the United States. Crit Care Med 2012, 40: 1072-1079. 10.1097/CCM.0b013e31823c8d03CrossRefPubMed
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Davidson JE, Jones C, Bienvenu OJ: Family response to critical illness: postintensive care syndrome-family. Crit Care Med 2012, 40: 618-624. 10.1097/CCM.0b013e318236ebf9CrossRefPubMed
Metadata
Title
Expect the unexpected: clinical trials are key to understanding post-intensive care syndrome
Authors
Michael F O'Connor
Mark E Nunnally
Publication date
01-06-2013
Publisher
BioMed Central
Published in
Critical Care / Issue 3/2013
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc12725

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