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01-06-2008 | Original Paper

Exercising Our Brains: How Physical Activity Impacts Synaptic Plasticity in the Dentate Gyrus

Authors: Brian R. Christie, Brennan D. Eadie, Timal S. Kannangara, Julie M. Robillard, James Shin, Andrea K. Titterness

Published in: NeuroMolecular Medicine | Issue 2/2008

Abstract

Exercise that engages the cardiovascular system has a myriad of effects on the body; however, we usually do not give much consideration to the benefits it may have for our minds. An increasing body of evidence suggests that exercise can have some remarkable effects on the brain. In this article, we will introduce how exercise can impact the capacity for neurons in the brain to communicate with one another. To properly convey this information, we will first briefly introduce the field of synaptic plasticity and then examine how the introduction of exercise to the experimental setting can actually alter the basic properties of synaptic plasticity in the brain. Next, we will examine some of the candidate physiological processes that might underlay these alterations. Finally, we will close by noting that, taken together, this data points toward our brains being dynamic systems that are in a continual state of flux and that physical exercise may help us to maximize the performance of both our body and our minds.

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Title: Exercising Our Brains: How Physical Activity Impacts Synaptic Plasticity in the Dentate Gyrus
Authors: Brian R. Christie
Brennan D. Eadie
Timal S. Kannangara
Julie M. Robillard
James Shin
Andrea K. Titterness
Publication date: 01-06-2008
Publisher: Humana Press Inc
Published in: NeuroMolecular Medicine / Issue 2/2008
Print ISSN: 1535-1084
Electronic ISSN: 1559-1174
DOI: https://doi.org/10.1007/s12017-008-8033-2

At a glance: The STEP trials

Springer Medicine

Exercising Our Brains: How Physical Activity Impacts Synaptic Plasticity in the Dentate Gyrus

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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Physical Activity and Neuroprotection in Amyotrophic Lateral Sclerosis

Physical Activity and the Regulation of Neurogenesis in the Adult and Aging Brain

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Exercise, Learned Helplessness, and the Stress-Resistant Brain

Central Mechanisms of HPA Axis Regulation by Voluntary Exercise

Neuroplasticity of Dopamine Circuits After Exercise: Implications for Central Fatigue