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Published in: Health and Quality of Life Outcomes 1/2012

Open Access 01-12-2012 | Research

Examining fatigue in COPD: development, validity and reliability of a modified version of FACIT-F scale

Authors: Khaled Al-shair, Hana Muellerova, Janelle Yorke, Stephen I Rennard, Emiel FM Wouters, Nicola A Hanania, Amir Sharafkhaneh, Jørgen Vestbo, for the ECLIPSE investigators

Published in: Health and Quality of Life Outcomes | Issue 1/2012

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Abstract

Introduction

Fatigue is a disruptive symptom that inhibits normal functional performance of COPD patients in daily activities. The availability of a short, simple, reliable and valid scale would improve assessment of the characteristics and influence of fatigue in COPD.

Methods

At baseline, 2107 COPD patients from the ECLIPSE cohort completed the Functional Assessment of Chronic Illness Therapy Fatigue (FACIT-F) scale. We used well-structured classic method, the principal components analysis (PCA) and Rasch analysis for structurally examining the 13-item FACIT-F.

Results

Four items were less able to capture fatigue characteristics in COPD and were deleted. PCA was applied to the remaining 9 items of the modified FACIT-F and resulted in three interpretable dimensions: i) general (5 items); ii) functional ability (2 items); and iii) psychosocial fatigue (2 items). The modified FACIT-F had high internal consistency (Cronbach's α = 0.91) and it did not fit a uni-dimensional Rasch model, confirming the prior output from the PCA. The correlations between total score and each dimension were ≥ 0.64 and within dimensions ≥0.43 (p < 0.001 for all).
The original and modified FACIT-F had significant convergent validity; its scores were associated with SGRQ total score (0.69 and 0.7) and mMRC dyspnoea scores (0.48 and 0.47), (p = <0.001 for all). The scale had meaningful discriminating ability in identifying patients with poor exercise performance and more depressive symptoms.

Conclusion

The original and modified FACIT-F are valid and reliable scales in COPD. The modified version is shorter and measures not only total fatigue but also its sub-components in COPD.
Appendix
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Metadata
Title
Examining fatigue in COPD: development, validity and reliability of a modified version of FACIT-F scale
Authors
Khaled Al-shair
Hana Muellerova
Janelle Yorke
Stephen I Rennard
Emiel FM Wouters
Nicola A Hanania
Amir Sharafkhaneh
Jørgen Vestbo
for the ECLIPSE investigators
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Health and Quality of Life Outcomes / Issue 1/2012
Electronic ISSN: 1477-7525
DOI
https://doi.org/10.1186/1477-7525-10-100

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