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Published in: BMC Public Health 1/2006

Open Access 01-12-2006 | Research article

Evolution of vaccination rates after the implementation of a free systematic pneumococcal vaccination in Catalonian older adults: 4-years follow-up

Authors: Angel Vila-Córcoles, Olga Ochoa-Gondar, Francisco Ester, Nuria Sarrá, Xabier Ansa, Neus Saún, EVAN Study Group

Published in: BMC Public Health | Issue 1/2006

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Abstract

Background

The systematic vaccination with 23-valent polysaccharide pneumococcal vaccine (PPV) was introduced as a strategic objective of health for all the people over 65 in Catalonia in 1999. We analysed the evolution of the pneumococcal vaccination rates from 2000 to 2003.

Methods

We conducted a retrospective population-based study including all the individuals 65 years or older assigned to 8 Primary Care Centres (PCCs) in Tarragona (Catalonia, Spain), who figured in the administrative population databases on 31 December 2003 (n = 10,410 persons). We assessed whether every person had received PPV during the last four years (2000 to 2003) or whether they had received it before January 2000. Data sources were the computerised clinical records of the 8 participating PCCs, which included adult vaccination registries and diagnoses coded of International Classification of Diseases 9th Review

Results

The overall vaccination uptake increased to 38.6% at the end of 2000. Global accumulated coverages increased more slowly the following years: 44.4% in 2001, 50.9% in 2002, and 53.1% at the end of 2003. Vaccine uptake varied significantly according to age (46.7% in people 65–74 years-old, 60.9% in people 75 years or more; p < 0.001) and number of diseases or risk factors (DRFs) for pneumonia (47.1% vaccinated in people without DRFs, 56.8% in patients with one DRF, and 62.2% in patients with two or more DRFs; p < 0.001). The highest coverages were observed among those patients with: diabetes (65.9%), active neoplasia (64.8%), history of stroke (63.7%), and chronic lung disease (63.5%). The lowest uptake was observed among smokers (48.7%).

Discussion

The pneumococcal vaccination coverage increased quickly after the introduction of the recommendation for free vaccination in all the elderly people (with and without risk factors), but two years after the improvement the coverage became stable and increased slowly.
Literature
1.
go back to reference Loeb M: Pneumonia in the elderly. Curr Opin Infect Dis. 2004, 17 (2): 127-30. 10.1097/00001432-200404000-00010.CrossRefPubMed Loeb M: Pneumonia in the elderly. Curr Opin Infect Dis. 2004, 17 (2): 127-30. 10.1097/00001432-200404000-00010.CrossRefPubMed
2.
go back to reference Fine MJ, Smith MA, Carson CA, Meffe F, Sankey SS, Weissfeld LA, Detsky AS, Kapoor WN: Efficacy of pneumococcal vaccination in adults. A meta-analysis of randomized controlled trials. Arch Intern Med. 1994, 154: 2666-77.CrossRefPubMed Fine MJ, Smith MA, Carson CA, Meffe F, Sankey SS, Weissfeld LA, Detsky AS, Kapoor WN: Efficacy of pneumococcal vaccination in adults. A meta-analysis of randomized controlled trials. Arch Intern Med. 1994, 154: 2666-77.CrossRefPubMed
3.
go back to reference Moore RA, Wiffen PJ, Lipsky BA: Are the neumococcal polysaccharide vaccines effective? Meta-analysis of the prospective trials. BCM Family Practice. 2000, 1-10.1186/1471-2296-1-1. Moore RA, Wiffen PJ, Lipsky BA: Are the neumococcal polysaccharide vaccines effective? Meta-analysis of the prospective trials. BCM Family Practice. 2000, 1-10.1186/1471-2296-1-1.
4.
go back to reference Cornu C, Yzebe D, Leophonte P, Gaillat J, Boissel JP, Cucherat M: Efficacy of pneumococcal polysaccharide vaccine in immunocompetent adults: a meta-analysis of randomized trials. Vaccine. 2001, 19: 4780-90. 10.1016/S0264-410X(01)00217-1.CrossRefPubMed Cornu C, Yzebe D, Leophonte P, Gaillat J, Boissel JP, Cucherat M: Efficacy of pneumococcal polysaccharide vaccine in immunocompetent adults: a meta-analysis of randomized trials. Vaccine. 2001, 19: 4780-90. 10.1016/S0264-410X(01)00217-1.CrossRefPubMed
5.
go back to reference Mangtani P, Cutts F, Hall AJ: Efficacy of polysaccharide pneumococcal vaccine in adults in more developed countries: the state of the evidence. Lancet Infect Dis. 2003, 3 (2): 71-8. 10.1016/S1473-3099(03)00514-0.CrossRefPubMed Mangtani P, Cutts F, Hall AJ: Efficacy of polysaccharide pneumococcal vaccine in adults in more developed countries: the state of the evidence. Lancet Infect Dis. 2003, 3 (2): 71-8. 10.1016/S1473-3099(03)00514-0.CrossRefPubMed
6.
go back to reference Dear K, Holden J, Andrews R, Tatham D: Vaccines for preventing pneumococcal infection in adults. Cochrane Database Syst Rev. 2003, 4: CD000422-PubMed Dear K, Holden J, Andrews R, Tatham D: Vaccines for preventing pneumococcal infection in adults. Cochrane Database Syst Rev. 2003, 4: CD000422-PubMed
7.
go back to reference Centers for Disease Control and Prevention: Prevention of pneumococcal disease: Recommendations of the advisory committee on immunisation practices (ACIP). MMWR. 1997, 46 (RR-08): 1-24. Centers for Disease Control and Prevention: Prevention of pneumococcal disease: Recommendations of the advisory committee on immunisation practices (ACIP). MMWR. 1997, 46 (RR-08): 1-24.
8.
go back to reference Task Force on Community Preventive Service: Recommendations regarding interventions to improve vaccinations coverage in children, adolescents and adults. Am J Prev Med. 2000, 18 (suppl): 92-140. Task Force on Community Preventive Service: Recommendations regarding interventions to improve vaccinations coverage in children, adolescents and adults. Am J Prev Med. 2000, 18 (suppl): 92-140.
9.
go back to reference Salleras Ll, Urbitzondo Ll, Fernández N, Comin E, Sanchez F, Batalla J: Pneumococcal vaccine in the elderly population'[in Spanish]. Med Clin (Barc). 2001, 116 (1): 18-23.CrossRef Salleras Ll, Urbitzondo Ll, Fernández N, Comin E, Sanchez F, Batalla J: Pneumococcal vaccine in the elderly population'[in Spanish]. Med Clin (Barc). 2001, 116 (1): 18-23.CrossRef
10.
go back to reference Vila A, Ochoa O, Hospital I, Bria X, Llor C, Montañés D, Grupo de Estudio EVAN-65: EVAN-65 project: evaluation of the effectiveness of pneumococcus vaccination in the elderly population over 65.[in Spanish]. Aten Primaria. 2004, 33 (3): 149-53. 10.1157/13058059.CrossRef Vila A, Ochoa O, Hospital I, Bria X, Llor C, Montañés D, Grupo de Estudio EVAN-65: EVAN-65 project: evaluation of the effectiveness of pneumococcus vaccination in the elderly population over 65.[in Spanish]. Aten Primaria. 2004, 33 (3): 149-53. 10.1157/13058059.CrossRef
11.
go back to reference Daniels NA, Nguyen TT, Gildengorin G, Perez-Stable EJ: Adult immunization in university-based primary care and specialty practices. J Am Geriatr Soc. 2004, 52 (6): 1007-12. 10.1111/j.1532-5415.2004.52273.x.CrossRefPubMed Daniels NA, Nguyen TT, Gildengorin G, Perez-Stable EJ: Adult immunization in university-based primary care and specialty practices. J Am Geriatr Soc. 2004, 52 (6): 1007-12. 10.1111/j.1532-5415.2004.52273.x.CrossRefPubMed
12.
go back to reference Center for Disease Control and Prevention: Influenza and pneumococcal vaccination coverage among persons aged > or = 65 years and persons aged 18–64 years with diabetes or asthma – United States, 2003. MMWR Morb Mortal Wkly Rep. 2004, 53 (43): 1007-12. Center for Disease Control and Prevention: Influenza and pneumococcal vaccination coverage among persons aged > or = 65 years and persons aged 18–64 years with diabetes or asthma – United States, 2003. MMWR Morb Mortal Wkly Rep. 2004, 53 (43): 1007-12.
13.
go back to reference Christenson B, Hedlund J, Lundbergh P, Ortqvist A: Additive preventive effect of influenza and pneumococcal vaccines in elderly persons. Eur Respir J. 2004, 23 (3): 363-8. 10.1183/09031936.04.00063504.CrossRefPubMed Christenson B, Hedlund J, Lundbergh P, Ortqvist A: Additive preventive effect of influenza and pneumococcal vaccines in elderly persons. Eur Respir J. 2004, 23 (3): 363-8. 10.1183/09031936.04.00063504.CrossRefPubMed
14.
go back to reference Andrews R, Counahan M, Hogg G, McIntyre PB: Effectiveness of a publicy funded pneumococcal vaccination program against invasive pneumococcal disease among the elederly in Victoria, Australia. Vaccine. 2004, 23: 132-138. 10.1016/j.vaccine.2004.06.016.CrossRefPubMed Andrews R, Counahan M, Hogg G, McIntyre PB: Effectiveness of a publicy funded pneumococcal vaccination program against invasive pneumococcal disease among the elederly in Victoria, Australia. Vaccine. 2004, 23: 132-138. 10.1016/j.vaccine.2004.06.016.CrossRefPubMed
15.
go back to reference Melegaro A, Edmunds WJ: The 23-valent pneumococcal polysaccharide vaccine. Part I. Efficacy of PPV in the elderly: a comparison of meta-analyses. Eur J Epidemiol. 2004, 19 (4): 353-63. 10.1023/B:EJEP.0000024701.94769.98.CrossRefPubMed Melegaro A, Edmunds WJ: The 23-valent pneumococcal polysaccharide vaccine. Part I. Efficacy of PPV in the elderly: a comparison of meta-analyses. Eur J Epidemiol. 2004, 19 (4): 353-63. 10.1023/B:EJEP.0000024701.94769.98.CrossRefPubMed
16.
go back to reference Fedson DS, Liss C: Precise answers to the wrong question: prospective clinical trials and the meta-analyses of pneumococcal vaccine in elderly and high-risk adults. Vaccine. 2004, 22 (8): 927-46. 10.1016/j.vaccine.2003.09.027.CrossRefPubMed Fedson DS, Liss C: Precise answers to the wrong question: prospective clinical trials and the meta-analyses of pneumococcal vaccine in elderly and high-risk adults. Vaccine. 2004, 22 (8): 927-46. 10.1016/j.vaccine.2003.09.027.CrossRefPubMed
17.
go back to reference Dominguez A, Salleras L, Cardenosa N, Ciruela P, Carmona G, Martinez A, Torner N, Fuentes M: The epidemiology of invasive Streptococcus pneumoniae disease in Catalonia (Spain). A hospital-based study. Vaccine. 2002, 20 (23–24): 2989-94. 10.1016/S0264-410X(02)00222-0.CrossRefPubMed Dominguez A, Salleras L, Cardenosa N, Ciruela P, Carmona G, Martinez A, Torner N, Fuentes M: The epidemiology of invasive Streptococcus pneumoniae disease in Catalonia (Spain). A hospital-based study. Vaccine. 2002, 20 (23–24): 2989-94. 10.1016/S0264-410X(02)00222-0.CrossRefPubMed
18.
go back to reference Nichol KL: The additive benefits of influenza and pneumococcal vaccinations during influenza seasons among elderly persons with chronic lung disease. Vaccine. 1999, 17 (1): S91-3. 10.1016/S0264-410X(99)00114-0.CrossRefPubMed Nichol KL: The additive benefits of influenza and pneumococcal vaccinations during influenza seasons among elderly persons with chronic lung disease. Vaccine. 1999, 17 (1): S91-3. 10.1016/S0264-410X(99)00114-0.CrossRefPubMed
Metadata
Title
Evolution of vaccination rates after the implementation of a free systematic pneumococcal vaccination in Catalonian older adults: 4-years follow-up
Authors
Angel Vila-Córcoles
Olga Ochoa-Gondar
Francisco Ester
Nuria Sarrá
Xabier Ansa
Neus Saún
EVAN Study Group
Publication date
01-12-2006
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2006
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-6-231

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