Published in:
01-03-2004 | Original
Evidence of myocardial ischaemia in severe scorpion envenomation
Myocardial perfusion scintigraphy study
Authors:
Mabrouk Bahloul, Chokri Ben Hamida, Khalil Chtourou, Hichem Ksibi, Hassen Dammak, Hatem Kallel, Adel Chaari, Hedi Chelly, Fadhel Guermazi, Noureddine Rekik, Mounir Bouaziz
Published in:
Intensive Care Medicine
|
Issue 3/2004
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Abstract
Objective
To explore the myocardial perfusion by thallium-201 scintigraphy for patients with evidence of myocardial damage after scorpion envenomation.
Design
Prospective study over 1-year period.
Setting
Medical intensive care unit of a university hospital (Sfax, Tunisia).
Patients
We have prospectively included six patients admitted for scorpion envenomation over a period of 1 year in the 22-bed intensive care unit (ICU) of our university hospital. The evidence of myocardial damage was confirmed by electrocardiography and echocardiography in all patients. Myocardial perfusion scintigraphy (201Tl scintigraphy) coupled with radionuclide ventriculography (99mTc) was performed for all patients, occurring 32 h on average (range 12–72 h) after the sting.
Results
Radionuclide ventriculography was abnormal in all cases; the abnormalities observed were similar to those observed by echocardiography. Moreover 201Tl scintigraphy showed evidence of myocardial hypoperfusion in all cases. The myocardial hypoperfusion grade and localisation were more marked in the abnormal localisation shown by echocardiography and electrocardiography, compared to the normal wall. Repeated studies, obtained only in two patients within 6 and 15 days, respectively, showed considerable, but not complete, improvement of wall motion and myocardial perfusion. Segments with improved perfusion showed greatly improved regional wall motion.
Conclusion
This study confirms the evidence of myocardial hypoperfusion after severe scorpion envenomation.