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Pediatric Nephrology
Published in: Pediatric Nephrology 11/2015

01-11-2015 | Educational Review

Evidence-based guidelines for the management of hypertension in children with chronic kidney disease

Author: Janis M. Dionne

Published in: Pediatric Nephrology | Issue 11/2015

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Abstract

Hypertension is common in children with chronic kidney disease and early evidence suggests that it is a modifiable risk factor for renal and cardiovascular outcomes. Recommendations for blood pressure management in children with chronic kidney disease can be found in various clinical practice guidelines including the 4th Task Force Report, the European Society of Hypertension pediatric recommendations, and the National Kidney Foundation Kidney Disease Outcomes Quality Initiative (K/DOQI) and Kidney Disease: Improving Global Outcomes (KDIGO) guidelines for the management of blood pressure in chronic kidney disease. Unfortunately, as pediatric trial evidence is limited, there are discrepancies in the recommendations that may lead to inconsistent clinical care and practice variation. This article reviews the strength of evidence behind each of the clinical practice guideline recommendations regarding blood pressure assessment, treatment targets, and first-line antihypertensive medications. The benefits and cautions of use of clinical practice guidelines are described with emphasis on the importance of reading beyond the summary statements.
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Metadata
Title
Evidence-based guidelines for the management of hypertension in children with chronic kidney disease
Author
Janis M. Dionne
Publication date
01-11-2015
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Nephrology / Issue 11/2015
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI
https://doi.org/10.1007/s00467-015-3077-7

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