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Journal of Cardiovascular Magnetic Resonance

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Open Access 01-12-2013 | Research

Evaluation of left ventricular diastolic function by fractional area change using cine cardiovascular magnetic resonance: a feasibility study

Authors: Satoshi Okayama, Tomoya Nakano, Shiro Uemura, Shinichi Fujimoto, Satoshi Somekawa, Makoto Watanabe, Tamio Nakajima, Yoshihiko Saito

Published in: Journal of Cardiovascular Magnetic Resonance | Issue 1/2013

Abstract

Background

Evaluation of left ventricular (LV) diastolic function is essential for the management of heart failure. We verified whether LV diastolic function could be evaluated by measuring the fractional area change (FAC) using cine cardiovascular magnetic resonance (CMR).

Methods

We collected clinical data from 59 patients who underwent echocardiography and cine CMR. Normal, impaired relaxation, pseudonormal, and restrictive LV filling were observed in 15, 28, 11, and 5 patients, respectively. We calculated FAC during the first 30% of diastole (diastolic-index%) in the short-axis view, by tracing the contours on only three MR cine images.

Results

The diastolic index was significantly lower (p < 0.0001) in patients with impaired relaxation (32.4 ± 7.5), pseudonormal filling (25.4 ± 5.6), and restrictive filling (9.5 ± 1.5) compared to those with normal diastolic function (67.7 ± 10.8), and the index decreased significantly with worsening of diastolic dysfunction. The diastolic index correlated positively with early diastolic mitral annular velocity measured by tissue Doppler imaging (r = 0.75, p < 0.0001), respectively.

Conclusions

Measurement of FAC can be useful for the evaluation of LV diastolic function using cine CMR.

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Title: Evaluation of left ventricular diastolic function by fractional area change using cine cardiovascular magnetic resonance: a feasibility study
Authors: Satoshi Okayama
Tomoya Nakano
Shiro Uemura
Shinichi Fujimoto
Satoshi Somekawa
Makoto Watanabe
Tamio Nakajima
Yoshihiko Saito
Publication date: 01-12-2013
Publisher: BioMed Central
Published in: Journal of Cardiovascular Magnetic Resonance / Issue 1/2013
Electronic ISSN: 1532-429X
DOI: https://doi.org/10.1186/1532-429X-15-87

At a glance: The STEP trials

Springer Medicine

Evaluation of left ventricular diastolic function by fractional area change using cine cardiovascular magnetic resonance: a feasibility study

Abstract

Background

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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