Skip to main content
Top
Published in: BMC Women's Health 1/2013

Open Access 01-12-2013 | Research article

Evaluation of factors associated with noncompliance in users of combined hormonal contraceptive methods: a cross-sectional study: results from the MIA study

Authors: Txantón Martínez-Astorquiza-Ortiz de Zarate, Teresa Díaz-Martín, Txantón Martínez-Astorquiza-Corral

Published in: BMC Women's Health | Issue 1/2013

Login to get access

Abstract

Background

Understanding contraception from the perspective of the user may help to improve compliance. The aim of this project was to determine the factors that influence the noncompliance in young women that use combined hormonal contraceptives (pill, patch or vaginal ring).

Methods

A nationwide cross-sectional multicenter epidemiology study. Physicians [obstetricians/gynecologists]) recorded socio-demographic, clinical and current contraception data of 8,762 women. Women completed a self-administered questionnaire on compliance. After the assessment of self-administrated questionnaire, the physicians reported on their recommendations on the possibility of changing the contraceptive.

Results

Fifty-two percent of women were noncompliant, mainly because of simple forgetfulness (pill, 74.9%; patch, 47.8%; vaginal ring, 69.1%). The percentage of noncompliant women was lower in vaginal ring users (26.6%) than in patch users (42.4%) or pill users (65.1%) (p < 0.0001). The most common course of action after noncompliance was to take/use the contraceptive as soon as possible. In the multiple logistic regression analysis, the use of the pill increased the probability of noncompliance compared with the patch and the vaginal ring (odds ratio [IC95%]: 2.53 (2.13-3.02) and 4.17 (3.68-4.73, respectively), and using the patch compared with the vaginal ring (1.65 (1.36-1.99)). Others factors associated with noncompliance were: high treatment duration, low degree of information on the contraceptive method, understanding of instructions on the contraceptive method, indifference to becoming pregnant, lack of partner support, not participation in selecting the method, not having a routine for taking treatment and difficulties remembering use the contraceptive method. Switching contraceptive method was proposed by the physicians to 43.2% of women (51.8% of pill users, 58.2% of patch users and 19.4% of vaginal ring users).

Conclusions

More than 50% of combined hormonal contraceptive users did not comply with the treatment regimen. The percentage of noncompliant women was lower between vaginal ring users. Understanding user’s reasons for noncompliance by the clinician and encouraging a collaborative approach can go a long way to improving compliance.
Appendix
Available only for authorised users
Literature
1.
go back to reference Skouby SO: Contraceptive use and behavior in the 21st century: a comprehensive study across five European countries. Eur J Contracept Reprod Health Care. 2004, 9: 57-68. 10.1080/13625180410001715681.CrossRefPubMed Skouby SO: Contraceptive use and behavior in the 21st century: a comprehensive study across five European countries. Eur J Contracept Reprod Health Care. 2004, 9: 57-68. 10.1080/13625180410001715681.CrossRefPubMed
2.
go back to reference Lete I, Bermejo R, Coll C, Dueñas JL, Doval JL, Martinez-Salmeán J, Parrilla JJ, Serrano I: Spanish population at risk of unwanted pregnancy: results of a national survey. Eur J Contracept Reprod Health Care. 2003, 8: 75-79.CrossRefPubMed Lete I, Bermejo R, Coll C, Dueñas JL, Doval JL, Martinez-Salmeán J, Parrilla JJ, Serrano I: Spanish population at risk of unwanted pregnancy: results of a national survey. Eur J Contracept Reprod Health Care. 2003, 8: 75-79.CrossRefPubMed
3.
go back to reference Darney PD: A hormonal contraception update 2010: a decade of innovation & transformation. Am J Obstet Gynecol. 2011, 205: S1-S24.CrossRef Darney PD: A hormonal contraception update 2010: a decade of innovation & transformation. Am J Obstet Gynecol. 2011, 205: S1-S24.CrossRef
4.
go back to reference Rosenberg MJ, Waugh MS, Long S: Unintended pregnancies and use, misuse and discontinuation of oral contraceptives. J Reprod Med. 1995, 40: 355-360.PubMed Rosenberg MJ, Waugh MS, Long S: Unintended pregnancies and use, misuse and discontinuation of oral contraceptives. J Reprod Med. 1995, 40: 355-360.PubMed
5.
go back to reference Rosenberg M, Waugh MS: Causes and consequences of oral contraceptive noncompliance. Am J Obstet Gynecol. 1999, 180: S276-S279. 10.1016/S0002-9378(99)70718-0.CrossRef Rosenberg M, Waugh MS: Causes and consequences of oral contraceptive noncompliance. Am J Obstet Gynecol. 1999, 180: S276-S279. 10.1016/S0002-9378(99)70718-0.CrossRef
6.
go back to reference Rosenberg MJ, Waugh M, Meehan T: Use and misuse of oral contraceptives: risk indicators for poor pill taking and discontinuation. Contraception. 1995, 51: 283-288. 10.1016/0010-7824(95)00074-K.CrossRefPubMed Rosenberg MJ, Waugh M, Meehan T: Use and misuse of oral contraceptives: risk indicators for poor pill taking and discontinuation. Contraception. 1995, 51: 283-288. 10.1016/0010-7824(95)00074-K.CrossRefPubMed
7.
go back to reference Halpern V, Lopez LM, Grimes DA, Gallo MF: Strategies to improve adherence and acceptability of hormonal methods of contraception. Cochrane Database Syst Rev. 2011, 4: CD004317 Halpern V, Lopez LM, Grimes DA, Gallo MF: Strategies to improve adherence and acceptability of hormonal methods of contraception. Cochrane Database Syst Rev. 2011, 4: CD004317
8.
go back to reference Lopez LM, Grimes DA, Gallo MF, Schulz KF: Skin patch and vaginal ring versus combined oral contraceptives for contraception. Cochrane Database Syst Rev. 2008, 1: CD003552 Lopez LM, Grimes DA, Gallo MF, Schulz KF: Skin patch and vaginal ring versus combined oral contraceptives for contraception. Cochrane Database Syst Rev. 2008, 1: CD003552
9.
go back to reference Bitzer J, Simon JA: Current issues and available options in combined hormonal contraception. Contraception. 2011, 84: 342-356. 10.1016/j.contraception.2011.02.013.CrossRefPubMed Bitzer J, Simon JA: Current issues and available options in combined hormonal contraception. Contraception. 2011, 84: 342-356. 10.1016/j.contraception.2011.02.013.CrossRefPubMed
10.
go back to reference Egarter C, Frey TB, Bitzer J, Kaminskyy V, Oddens BJ, Prilepskaya V, Yeshaya A, Marintcheva-Petrova M, Weyers S: Women’s Perceptions and reasons for choosing the pill, patch, or ring in the CHOICE study: a cross-sectional survey of contraceptive method selection after counseling. BMC Womens Health. 2013, 13: 9-10.1186/1472-6874-13-9.CrossRefPubMedPubMedCentral Egarter C, Frey TB, Bitzer J, Kaminskyy V, Oddens BJ, Prilepskaya V, Yeshaya A, Marintcheva-Petrova M, Weyers S: Women’s Perceptions and reasons for choosing the pill, patch, or ring in the CHOICE study: a cross-sectional survey of contraceptive method selection after counseling. BMC Womens Health. 2013, 13: 9-10.1186/1472-6874-13-9.CrossRefPubMedPubMedCentral
11.
go back to reference Lete I, Doval JL, Pérez-Campos E, Letxundi R, Correa M, de la Viuda E, Gómez MA, González JV, Martínez MT, Mendoza N, Robledo J: Self-described impact of noncompliance among users of a combined hormonal contraceptive method. Contraception. 2008, 77: 276-282. 10.1016/j.contraception.2007.11.009.CrossRefPubMed Lete I, Doval JL, Pérez-Campos E, Letxundi R, Correa M, de la Viuda E, Gómez MA, González JV, Martínez MT, Mendoza N, Robledo J: Self-described impact of noncompliance among users of a combined hormonal contraceptive method. Contraception. 2008, 77: 276-282. 10.1016/j.contraception.2007.11.009.CrossRefPubMed
12.
go back to reference Lete I, Doval JL, Pérez-Campos E, Sánchez-Borrego R, Correa M, de la Viuda E, Gómez MA, González JV, Lertxundi R, Martínez MT, Mendoza N, Robledo J: Factors affecting women's selection of a combined hormonal contraceptive method: the TEAM-06 Spanish cross-sectional study. Contraception. 2007, 76: 77-83. 10.1016/j.contraception.2007.04.014.CrossRefPubMed Lete I, Doval JL, Pérez-Campos E, Sánchez-Borrego R, Correa M, de la Viuda E, Gómez MA, González JV, Lertxundi R, Martínez MT, Mendoza N, Robledo J: Factors affecting women's selection of a combined hormonal contraceptive method: the TEAM-06 Spanish cross-sectional study. Contraception. 2007, 76: 77-83. 10.1016/j.contraception.2007.04.014.CrossRefPubMed
13.
go back to reference Oddson K, Leifels-Fischer B, de Melo NR, Wiel-Masson D, Benedetto C, Verhoeven CH, Dieben TO: Efficacy and safety of a contraceptive vaginal ring (NuvaRing) compared with a combined oral contraceptive: a 1-year randomized trial. Contraception. 2005, 71: 176-182. 10.1016/j.contraception.2004.09.001.CrossRef Oddson K, Leifels-Fischer B, de Melo NR, Wiel-Masson D, Benedetto C, Verhoeven CH, Dieben TO: Efficacy and safety of a contraceptive vaginal ring (NuvaRing) compared with a combined oral contraceptive: a 1-year randomized trial. Contraception. 2005, 71: 176-182. 10.1016/j.contraception.2004.09.001.CrossRef
14.
15.
go back to reference Jakimiuk AJ, Crosignani PG, Chernev T, Prilepskaya V, Bergmans P, Von Poncet M, Marelli S, Lee EJ: High levels of women's satisfaction and compliance with transdermal contraception: results from a European multinational, 6-month study. Gynecol Endocrinol. 2011, 27: 849-856. 10.3109/09513590.2010.538095.CrossRefPubMed Jakimiuk AJ, Crosignani PG, Chernev T, Prilepskaya V, Bergmans P, Von Poncet M, Marelli S, Lee EJ: High levels of women's satisfaction and compliance with transdermal contraception: results from a European multinational, 6-month study. Gynecol Endocrinol. 2011, 27: 849-856. 10.3109/09513590.2010.538095.CrossRefPubMed
16.
go back to reference Potter L, Oakley D, de Leon-Wong E, Cañamar R: Measuring compliance among oral contraceptive users. Fam Plann Perspect. 1996, 28 (4): 154-158. 10.2307/2136191.CrossRefPubMed Potter L, Oakley D, de Leon-Wong E, Cañamar R: Measuring compliance among oral contraceptive users. Fam Plann Perspect. 1996, 28 (4): 154-158. 10.2307/2136191.CrossRefPubMed
17.
go back to reference Aubeny E, Buhler M, Colau JC, Vicaut E, Zadikian M, Childs M, The Coraliance study: non-compliant behavior: Results after a 6-month follow-up of patients on oral contraceptives. Eur J Contracept Reprod Health Care. 2004, 9 (4): 267-277. 10.1080/13625180400017776.CrossRefPubMed Aubeny E, Buhler M, Colau JC, Vicaut E, Zadikian M, Childs M, The Coraliance study: non-compliant behavior: Results after a 6-month follow-up of patients on oral contraceptives. Eur J Contracept Reprod Health Care. 2004, 9 (4): 267-277. 10.1080/13625180400017776.CrossRefPubMed
18.
go back to reference Kalmuss D, Cushman L, Robilotto T, Davis A, Cwiak C, Stuart G, Zieman M, Edwards S, Heartwell S, Westhoff CL: Oral contraceptive discontinuation: do side effects matter?. Am J Obstet Gynecol. 2007, 196: 6-7. Kalmuss D, Cushman L, Robilotto T, Davis A, Cwiak C, Stuart G, Zieman M, Edwards S, Heartwell S, Westhoff CL: Oral contraceptive discontinuation: do side effects matter?. Am J Obstet Gynecol. 2007, 196: 6-7.
19.
go back to reference Aubeny E, Buhler M, Colau JC, Vicaut E, Zadikian M, Childs M: Oral contraception: patterns of non-compliance. The Coraliance study. Eur J Contracept Reprod Health Care. 2002, 7: 155-161.CrossRefPubMed Aubeny E, Buhler M, Colau JC, Vicaut E, Zadikian M, Childs M: Oral contraception: patterns of non-compliance. The Coraliance study. Eur J Contracept Reprod Health Care. 2002, 7: 155-161.CrossRefPubMed
20.
go back to reference Weisberg F, Bouchard C, Moreau M, Audet MC, Mawdsley S, Dattani D, Dinniwell J, Horbay GL, NRGEEP-CON-401 Study Group: Preference for and satisfaction of Canadian women with the Transdermal contraceptive patch versus previous contraceptive method: an open label, multicentre study. J Obstet Gynaecol Can. 2005, 27: 350-359.CrossRefPubMed Weisberg F, Bouchard C, Moreau M, Audet MC, Mawdsley S, Dattani D, Dinniwell J, Horbay GL, NRGEEP-CON-401 Study Group: Preference for and satisfaction of Canadian women with the Transdermal contraceptive patch versus previous contraceptive method: an open label, multicentre study. J Obstet Gynaecol Can. 2005, 27: 350-359.CrossRefPubMed
21.
go back to reference Archer DF, Bigrigg A, Smallwood GH, Shangold GA, Creasy GW, Fisher AC: Assessment of compliance with a weekly contraceptive patch (Ortho Evra/Evra) among North American women. Fertil Steril. 2002, 77: S27-S31.CrossRefPubMed Archer DF, Bigrigg A, Smallwood GH, Shangold GA, Creasy GW, Fisher AC: Assessment of compliance with a weekly contraceptive patch (Ortho Evra/Evra) among North American women. Fertil Steril. 2002, 77: S27-S31.CrossRefPubMed
22.
go back to reference Milsom I, Lete I, Bjertnaes A, Rokstad K, Lindh I, Gruber CJ, Birkhäuser MH, Aubeny E, Knudsen T, Bastianelli C: Effects on cycle control and bodyweight of the combined contraceptive ring, NuvaRing, versus an oral contraceptive containing 30 microg ethinyl estradiol and 3 mg drospirenone. Hum Reprod. 2006, 21: 2304-2311. 10.1093/humrep/del162.CrossRefPubMed Milsom I, Lete I, Bjertnaes A, Rokstad K, Lindh I, Gruber CJ, Birkhäuser MH, Aubeny E, Knudsen T, Bastianelli C: Effects on cycle control and bodyweight of the combined contraceptive ring, NuvaRing, versus an oral contraceptive containing 30 microg ethinyl estradiol and 3 mg drospirenone. Hum Reprod. 2006, 21: 2304-2311. 10.1093/humrep/del162.CrossRefPubMed
23.
go back to reference Lara-Torre E, Spotswood L, Correia N, Weiss PM: Intrauterine contraception in adolescents and young women: a descriptive study of use, side effects, and compliance. J Pediatr Adolesc Gynecol. 2011, 24: 39-41. 10.1016/j.jpag.2010.07.001.CrossRefPubMed Lara-Torre E, Spotswood L, Correia N, Weiss PM: Intrauterine contraception in adolescents and young women: a descriptive study of use, side effects, and compliance. J Pediatr Adolesc Gynecol. 2011, 24: 39-41. 10.1016/j.jpag.2010.07.001.CrossRefPubMed
24.
go back to reference Halpern V, Lopez LM, Grimes DA, Gallo MF: Strategies to improve adherence and acceptability of hormonal methods of contraception. Cochrane Database Syst Rev. 2011, 13: CD004317 Halpern V, Lopez LM, Grimes DA, Gallo MF: Strategies to improve adherence and acceptability of hormonal methods of contraception. Cochrane Database Syst Rev. 2011, 13: CD004317
25.
go back to reference Blanc AK, Curtis SL, Croft TN: Monitoring contraceptive continuation: links to fertility outcomes and quality of care. Stud Fam Plann. 2002, 33: 127-140. 10.1111/j.1728-4465.2002.00127.x.CrossRefPubMed Blanc AK, Curtis SL, Croft TN: Monitoring contraceptive continuation: links to fertility outcomes and quality of care. Stud Fam Plann. 2002, 33: 127-140. 10.1111/j.1728-4465.2002.00127.x.CrossRefPubMed
26.
go back to reference Grove D, Hooper DJ: Doctor contraceptive-prescribing behaviour and women's attitudes towards contraception: two European surveys. J Eval Clin Pract. 2011, 17: 493-502. 10.1111/j.1365-2753.2010.01465.x.CrossRefPubMed Grove D, Hooper DJ: Doctor contraceptive-prescribing behaviour and women's attitudes towards contraception: two European surveys. J Eval Clin Pract. 2011, 17: 493-502. 10.1111/j.1365-2753.2010.01465.x.CrossRefPubMed
27.
go back to reference Durant RH, Jay MS, Linder CW, Shofitt T, Litt I: Influence of psychosocial factors on adolescent compliance with oral contraceptives. J Adolesc Health Care. 1984, 5: 1-6. 10.1016/S0197-0070(84)80237-5.CrossRefPubMed Durant RH, Jay MS, Linder CW, Shofitt T, Litt I: Influence of psychosocial factors on adolescent compliance with oral contraceptives. J Adolesc Health Care. 1984, 5: 1-6. 10.1016/S0197-0070(84)80237-5.CrossRefPubMed
28.
go back to reference Rosenberg MJ, Waugh MS: Oral contraceptive discontinuation: a prospective evaluation of frequency and reasons. Am J Obstet Gynecol. 1998, 179: 577-582. 10.1016/S0002-9378(98)70047-X.CrossRefPubMed Rosenberg MJ, Waugh MS: Oral contraceptive discontinuation: a prospective evaluation of frequency and reasons. Am J Obstet Gynecol. 1998, 179: 577-582. 10.1016/S0002-9378(98)70047-X.CrossRefPubMed
Metadata
Title
Evaluation of factors associated with noncompliance in users of combined hormonal contraceptive methods: a cross-sectional study: results from the MIA study
Authors
Txantón Martínez-Astorquiza-Ortiz de Zarate
Teresa Díaz-Martín
Txantón Martínez-Astorquiza-Corral
Publication date
01-12-2013
Publisher
BioMed Central
Published in
BMC Women's Health / Issue 1/2013
Electronic ISSN: 1472-6874
DOI
https://doi.org/10.1186/1472-6874-13-38

Other articles of this Issue 1/2013

BMC Women's Health 1/2013 Go to the issue