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01-07-2012 | Original Contribution

Evaluation of attitudes towards treatment in adolescents with attention deficit hyperactivity disorder (ADHD)

Authors: Maite Ferrin, Miguel Ruiz-Veguilla, Maria Blanc-Betes, Samaa El Abd, Teresa Lax-Pericall, Maxine Sinclair, Eric Taylor

Published in: European Child & Adolescent Psychiatry | Issue 7/2012

Abstract

A substantial proportion of adolescents with attention deficit hyperactivity disorder (ADHD) do not appropriately adhere to prescribed treatments, especially to pharmacological treatments. It is important to disentangle the specific attitudes that contribute to treatment adherence. A 33-item questionnaire was applied to 120 adolescents diagnosed with ADHD and their respective parents. Reliability of the scale was explored using factor analysis, Cronbach’s alpha, and test–retest. Validity was explored by face validity and the known-groups method. For the young people’s version, three main dimensions (preoccupations, insight and self-concept) emerged. The parents’ version showed six main dimensions (child’s personal attitudes, worries, social stigma, insight, future side effects and knowledge). The potential of this questionnaire to explore the attitudes of patients and their families towards treatments and for clinicians to predict treatment adherence is discussed.

Aagaard L, Hansen EH (2011) Prescribing of medicines in the Danish paediatric population outwith the licensed age group: characteristics of adverse drug reactions. Br J Clin Pharmacol 71:751–757PubMedCrossRef

Allison PD (2000) Multiple imputation for missing data: a cautionary tale. Sociol Methods Res 28:301–309CrossRef

Amador XF, Gorman JM (1998) Psychopathologic domains and insight in schizophrenia. Psych Clin N Am 21:27–42CrossRef

American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders: DSM-IV-TR (4th (text revision). American Psychiatric Association, Washington

Atkins L, Fallowfield L (2006) Intentional and non-intentional non-adherence to medication amongst breast cancer patients. Eur J Cancer 42:2271–2276PubMedCrossRef

Baxley GB, Turner PF (1978) Hyperactive children’s knowledge and attitudes concerning drug treatment. J Pediatr Psychol 3:172–176CrossRef

Brown RT, Borden KA, Clingerman SR (1985) Adherence to methylphenidate therapy in a pediatric population: a preliminary investigation. Psychopharmacol Bull 21:28–36PubMed

Brown RT, Borden KA, Wynne ME, Spunt AL, Clingerman SR (1987) Compliance with pharmacological and cognitive treatments for attention deficit disorder. J Am Acad Chil Adolesc Psych 26:521–526CrossRef

Buchanan A (1992) A two-year prospective study of treatment compliance in patients with schizophrenia. Psychol Med 22:787–797PubMedCrossRef

10.

Buchanan AW (1996) Compliance with treatment in schizophrenia. Psychology Press, Hove

11.

Buckley P (2009) Adherence to mental health treatment. Oxford University Press, New York

12.

Bush PJ, Iannotti RJ (1990) A children’s health belief model. Med Care 28:69–86PubMedCrossRef

13.

Cattell RB (1966) The scree test for the number of factors. Multivar Behav Res 1:245–276CrossRef

14.

Charach A, Ickowicz A, Schachar R (2004) Stimulant treatment over five years: adherence, effectiveness, and adverse effects. J Am child Adolesc Psych 43:559–567CrossRef

15.

Cicchetti DV, Sparrow SA (1981) Developing criteria for establishing interrater reliability of specific items: applications to assessment of adaptive behavior. Am J Ment Def 86:127–137

16.

Clavenna A, Bonati M (2009) Drug prescriptions to outpatient children: a review of the literature. Eur J Clin Pharmacol 65:749–755PubMedCrossRef

17.

Cohen J (1977) Statistical power analysis for the behavioral sciences (revised edition). Academic Press, New York

18.

Dempster AP, Laird NM, Rubin DB (1977) Maximum likelihood from incomplete data via the EM algorithm. J Royal Stat Soc B 39:1–38

19.

DeVellis RF (2003) Scale development: theory and applications, 2nd edn. Sage Publications, Thousand Oaks

20.

Efron D, Jarman FC, Barker MJ (1998) Child and parent perceptions of stimulant medication treatment in attention deficit hyperactivity disorder. J Pediatr Child Health 34:288–292CrossRef

21.

Ferrín M (2006) Treatment adherence and attitudes towards treatment in ADHD adolescents: developing a questionnaire. Dissertation, Institute of Psychiatry at the Maudsley, King’s College London, London, UK

22.

Ferrin M, Gledhill J, Kramer T, Garralda M (2009) Factors influencing primary care attendance in adolescents with high levels of depressive symptoms. Soc Psychiatry Epidemiol 44:825–833CrossRef

23.

Ferrin M, Taylor E (2011) Child and caregiver issues in the treatment of ADHD: education, adherence and treatment choice. Future Neurol 6:399–413CrossRef

24.

Firestone P (1982) Factors associated with children’s adherence to stimulant medication. Am J Ortopsych 52:447–457CrossRef

25.

Ford T, Goodman R, Meltzer H (2003) The British Child and Adolescent Mental Health Survey 1999: The Prevalence of DSM-IV Disorders. J Acad Child Adolesc Psych 42:1203–1211CrossRef

26.

Gorsuch RL (1974) Factor analysis. Saunders, Philadelphia

27.

Graham J, Banaschewski T, Buitelaar J, Coghill D, Danckaerts M, Dittmann RW, Dopfner M, Hamilton R, Hollis C, Holtmann M, Hulpke-Wette M, Lecendreux M, Rosenthal E, Rothenberger A, Santosh P, Sergeant J, Simonoff E, Sonuga-Barke E, Wong ICK, Zuddas A, Steinhausen HC, Taylor E (2011) European guidelines on managing adverse effects of medication for ADHD. Eur Child Adolesc Psychia 21:17–37CrossRef

28.

Hack S, Chow B (2001) Pediatric psychotropic medication compliance: A literature review and research-based suggestions for improving treatment compliance. J Child Adolesc Psychopharm 11:59–67CrossRef

29.

Harpur RA, Thompson M, Daley D, Abikoff H, Sonuga-Barke EJ (2008) The attention-deficit/hyperactivity disorder medication-related attitudes of patients and their parents. J Child Adolesc Psychopharm 18:461–473CrossRef

30.

Hill P, Taylor E (2001) An auditable protocol for treating attention deficit/hyperactivity disorder. Arch Dis Child 84:404–409PubMedCrossRef

31.

Hogan TP, Awad AG, Eastwood R (1983) A self-report scale predictive of drug compliance in schizophrenics: reliability and discriminative validity. Psychol Med 13:177–183PubMedCrossRef

32.

Horne R, Weinman J, Hankins M (1999) The beliefs about medicines questionnaire: the development and evaluation of a NE10, 10, 10, w method for assessing the cognitive representation of medication. Psychol Health 14:1–24CrossRef

33.

Irvine SH, Kyllonen PC (2002) Item generation for test development. L. Erlbaum Associates, Mahwah

34.

Johnston C, Fine S (1993) Methods of evaluating methylphenidate in children with attention deficit hyperactivity disorder: acceptability, satisfaction, and compliance. J Pediatr Psychol 18:717–730PubMedCrossRef

35.

Kampman O, Laippala P, Vaananen J, Koivisto E, Kiviniemi P, Kilkku N (2002) Indicators of medication compliance in first-episode psychosis. Psychiatr Res 110:39–48CrossRef

36.

Kline P (1998) The new psychometrics: science, psychology and measurement. Routledge, London

37.

McNeal RE, Roberts MC, Barone VJ (2000) Mothers’ and children’s perceptions of medication for children with attention-deficit hyperactivity disorder. Child Psychiatry Hum Dev 30:173–187PubMedCrossRef

38.

Molina BSG, Hinshaw SP, Swanson JM, Eugene L, Arnold MD, Vitiello B, Jensen PS, Epstein JN, Hoza B, Hechtman L, Abikoff HB, Elliott GR, Greenhill LL, Newcorn JH, Wells KC, Wigal T, Gibbons RD, Hur K, Houck PR, MS and The MTA Cooperative Group (2009) The MTA at 8 years: prospective follow-up of children treated for combined type ADHD in a multisite study. J Am Acad Child Adolesc Psychiatry 48: 484–500

39.

Montoya A, Colom F, Ferrin M (2011) Is psychoeducation for parents and teachers of children and adolescents with ADHD efficacious? a systematic literature review. Eur Psych 26:166–175CrossRef

40.

MTA Cooperative Group multimodal treatment study of children with attention deficit/hyperactivity disorder (1999) A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. Arch Gen Psych 56:1073–1086CrossRef

41.

MTA Cooperative Group multimodal treatment study of children with attention deficit/hyperactivity dsiorder (1999) Moderators and mediators of treatment response for children with attention-deficit/hyperactivity disorder. Arch Gen Psych 56:1088–2066CrossRef

42.

Osterberg L, Blaschke T (2005) Adherence to medication. New Eng J Med 353:487–497PubMedCrossRef

43.

Parellada M, Fraguas D, Bombin I, Otero S, Castro-Fornieles J, Baeza I (2009) Insight correlates in child- and adolescent-onset first episodes of psychosis: results from the CAFEPS study. Psychol Med 39:1433–1445PubMedCrossRef

44.

Portney LG, Watkins MP (2009) Foundations of clinical research: applications to practice, 3rd edn. Prentice Hall, Upper Saddle River

45.

Preacher KJ, MacCallum RC (2002) Exploratory factor analysis in behavior genetics research: factor recovery with small sample sizes. Behav Gen 32:153–161CrossRef

46.

Singh AL, Waldman ID (2010) The etiology of associations between negative emotionality and childhood externalizing disorders. J Abnorm Psychol 119:376–388PubMedCrossRef

47.

Sleator EK, Ullmann RK, von Neumann A (1982) How do hyperactive children feel about taking stimulants and will they tell the doctor? Clin Pediatrics 21:474–479CrossRef

48.

Steiner D, Norman G (2003) Measurement Scales: a practical guide to their development and use. Oxford Medical Publications, Oxford

49.

Taylor E, Dopfner M, Sergeant J, Asherson P, Banaschewski T, Buitelaar J (2004) European clinical guidelines for hyperkinetic disorder—first upgrade. Eur Child Adolesc Psychiatry 13(Suppl 1):17–30

50.

Taylor E, Schachar R, Thorley G, Wieselberg M (1986) Conduct disorder and hyperactivity: I. Separation of hyperactivity and antisocial conduct in British child psychiatric patients. Br J Psych: J Ment Sci 149:760–767CrossRef

51.

Taylor N, Fauset A, Harpin V (2010) Young adults with ADHD: an analysis of their service needs on transfer to adult services. Arch Dis Child 95:513–517PubMedCrossRef

52.

Thiruchelvam D, Charach A, Schachar RJ (2001) Moderators and mediators of long-term adherence to stimulant treatment in children with ADHD. J Acad Child Adolesc Psych 40:922–928CrossRef

53.

Thompson K, Kulkarni J, Sergejew AA (2000) Reliability and validity of a new medication adherence rating scale (MARS) for the psychoses. Schizophr Res 42:241–247PubMedCrossRef

54.

Urquhart G, Sinclair S, Fraser N (2007) Children’s attitudes and behavioural intentions towards a peer with symptoms of ADHD: does the addition of a diagnostic label make a difference? J Child Health Care, 11: 98–11

55.

Volkow ND, Swanson JM (2008) Does childhood treatment of ADHD with stimulant medication affect substance abuse in adulthood? Am J Psych 165:553–555CrossRef

56.

Weir JP (2005) Quantifying test–retest reliability using the intraclass correlation coefficient and the SEM. J Strength Cond Res 19:231–240PubMed

57.

Wong IC, Asherson P, Bilbow A, Clifford S, Coghill D, DeSoysa R, Hollis C, McCarthy S, Murray M, Planner C, Potts L, Sayal K, Taylor E (2009) Cessation of attention deficit hyperactivity disorder drugs in the young (CADDY)—a pharmacoepidemiological and qualitative study. Health Technol Assess 13:1–120

58.

Yen M, Lo LH (2002) Examining test–retest reliability: an intra-class correlation approach. Nurs Res 51:59–62PubMedCrossRef

Title: Evaluation of attitudes towards treatment in adolescents with attention deficit hyperactivity disorder (ADHD)
Authors: Maite Ferrin
Miguel Ruiz-Veguilla
Maria Blanc-Betes
Samaa El Abd
Teresa Lax-Pericall
Maxine Sinclair
Eric Taylor
Publication date: 01-07-2012
Publisher: Springer-Verlag
Published in: European Child & Adolescent Psychiatry / Issue 7/2012
Print ISSN: 1018-8827
Electronic ISSN: 1435-165X
DOI: https://doi.org/10.1007/s00787-012-0277-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Evaluation of attitudes towards treatment in adolescents with attention deficit hyperactivity disorder (ADHD)

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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