Published in:
Open Access
01-12-2015 | Poster presentation
Estimating the effect of “treatment in the treated” - instrumental variable analysis vs conventional regression methods in the titre-2 trial in cardiac surgery
Authors:
Chris Rogers, Katie Pike, Jonathan Sterne, Barney Reeves
Published in:
Trials
|
Special Issue 2/2015
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Excerpt
Perioperative anaemia is associated with adverse outcomes after cardiac surgery but, paradoxically, observational analyses have shown that red cell transfusion is associated with worse clinical outcomes. TITRe2 tested the hypothesis that a restrictive threshold for transfusion would reduce post-operative morbidity compared to a liberal threshold. …