Published in:
24-01-2024 | Esophageal Cancer | ASO Author Reflections
ASO Author Reflections: Significance of Skeletal Muscle Loss After Neoadjuvant Chemoradiation for Esophageal Cancer
Authors:
Xin Xiao, MD, Pin-Hao Fang, MD, Jian-Feng Zhou, MD, Yong Yuan, MD, PhD
Published in:
Annals of Surgical Oncology
|
Issue 6/2024
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Excerpt
Many studies and meta-analyses had proven that esophageal cancer patients with sarcopenia had a disadvantage on surgical morbidity and survival benefit.
1,2 Sarcopenia, a time-specific body composition, could be diagnosed through assessing skeletal muscle index (SMI). However, the addition of neoadjuvant therapy might contribute to body compositional changes and influence patients’ nutritional status for locally advanced esophageal cancer.
3,4 It was more important to investigate the changes in skeletal muscle index during neoadjuvant therapy, instead of solely focusing on sarcopenia status at presentation. …