Published in:
01-12-2008 | Erratum
Erratum to: The role of corticosteroids in severe community-acquired pneumonia: a systematic review
Published in: Critical Care | Issue 6/2008
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Following the publication of the above article [1], we noticed that in Table 1, concerning the data of the study from Garcia-Vidal the dose of methylprednisolone is not 14.5 mg/day but 45 mg/day.
Table 1
Recent literature on the role of corticosteroids in severe community-acquired pneumonia
|
Reference
|
Study design
|
Sample size, number
|
Patient selection
|
Corticosteroids (drug/regimen)
|
Primary endpoints
|
Level of evidence and recommendation
|
|---|---|---|---|---|---|---|
|
Marik, et al. [21]
|
Single-center RCT
|
30
|
Severe CAP
|
Hydrocortisone 10 mg/kg versus placebo 30 minutes before antibiotics
|
Mortality, clinical course, and serum TNF-α levels
|
Weak recommendation, moderate-quality evidence
|
|
Confalonieri, et al. [6]
|
Multicenter RCT
|
46
|
Severe CAP
|
Hydrocortisone 200 mg + hydrocortisone 10 mg/hour, for 7 days versus placebo
|
Mortality, clinical course, and Systemic inflammation
|
Strong recommendation, moderate-quality evidence
|
|
Mikami, et al. [20]
|
Open label RCT
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31
|
Moderate and severe CAP
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Prednisolone 40 mg qd, for 3 days versus placebo
|
Mortality and clinical course
|
Weak recommendation, low-quality evidence
|
|
Garcia-Vidal, et al. [19]
|
Retrospective cohort study
|
308
|
Severe CAP
|
Methylprednisolone 45 mg (or equivalent) qd for 11.4 days
|
Mortality
|
Strong recommendation, low-quality evidence
|