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01-05-2014 | Case Report

Erdheim–Chester disease with an 18F-fluorodeoxyglucose-avid breast mass and BRAF V600E mutation

Authors: Toshihiro Furuta, Shigeru Kiryu, Haruyasu Yamada, Masataka Hosoi, Mineo Kurokawa, Teppei Morikawa, Junji Shibahara, Kuni Ohtomo

Published in: Japanese Journal of Radiology | Issue 5/2014

Abstract

Erdheim–Chester disease (ECD) is a non-Langerhans cell histiocytosis. Herein we report a case of a 49-year-old woman who developed bilateral knee pain. Imaging procedures revealed multiple long bone lesions and a well-defined 18F-fluorodeoxyglucose-avid mass in the left breast. The breast mass was resected, and an open biopsy was performed on the right femoral lesion. Both specimens revealed involvement by histiocytic infiltrates with features suggestive of ECD. The BRAF V600E mutation was detected by DNA sequencing and immunohistochemistry.

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Title: Erdheim–Chester disease with an 18F-fluorodeoxyglucose-avid breast mass and BRAF V600E mutation
Authors: Toshihiro Furuta
Shigeru Kiryu
Haruyasu Yamada
Masataka Hosoi
Mineo Kurokawa
Teppei Morikawa
Junji Shibahara
Kuni Ohtomo
Publication date: 01-05-2014
Publisher: Springer Japan
Published in: Japanese Journal of Radiology / Issue 5/2014
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI: https://doi.org/10.1007/s11604-014-0295-z

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Erdheim–Chester disease with an 18F-fluorodeoxyglucose-avid breast mass and BRAF V600E mutation

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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