Top

Journal of Medical Case Reports

Published in:

Open Access 01-12-2016 | Case report

Epithelial-myoepithelial carcinoma arising from the subglottis: a case report and review of the literature

Authors: Hun-Jae Oh, Nam-yong Do, Keun-Hong Kee, Jun-Hee Park

Published in: Journal of Medical Case Reports | Issue 1/2016

Abstract

Background

Epithelial-myoepithelial carcinoma is an extremely rare disease that usually occurs in the parotid gland but can occur in a variety of sites such as the nasal cavity, paranasal sinus, and base of the tongue.

Case presentation

We report a rare case of epithelial-myoepithelial carcinoma, which developed in the subglottic region. A 78-year-old Korean woman visited our hospital complaining of hoarseness, which had developed 1 month previously. Flexible laryngoscopy showed a round mass that blocked approximately 80 % of the tracheal diameter. Complete excision of the mass was carried out under general anesthesia, using a transoral approach. Epithelial-myoepithelial carcinoma was diagnosed following immunohistochemical analysis.

Conclusions

We report a rare case of epithelial-myoepithelial carcinoma that occurred in the subglottic region. To the best of our knowledge, only one other case has been reported since this disease was first identified approximately 40 years ago.

Donath K, Seifert G, Schmitz R. Diagnosis and ultrastructure of the tubular carcinoma of salivary gland ducts. Epithelial-myoepithelial carcinoma of the intercalated ducts. Virchows Archiv A Pathol Pathol Anat. 1972;356(1):16–31.CrossRef

Batsakis JG, el-Naggar AK, Luna MA. Epithelial-myoepithelial carcinoma of salivary glands. Ann Otol Rhinol Laryngol. 1992;101(6):540–2.CrossRefPubMed

Lampe H, Ruby RR, Greenway RE, DeRose G, Wysocki GP. Epithelial-myoepithelial carcinoma of the salivary gland. J Otolaryngol. 1984;13(4):247–51.PubMed

Patra SK, Panda NK, Saikia UN. Epithelial-myoepithelial carcinoma of the maxillary sinus: a rare case. Laryngoscope. 2012;122(7):1579–81.CrossRefPubMed

Konoglou M, Cheva A, Zarogoulidis P, Porpodis K, Pataka A, Mpaliaka A, et al. Epithelial-myoepithelial carcinoma of the trachea-a rare entity case report. J Thor Dis. 2014;6 Suppl 1:S194–9.

Mikaelian DO, Contrucci RB, Batsakis JG. Epithelial-myoepithelial carcinoma of the subglottic region: a case presentation and review of the literature. Otolaryngol Head Neck Surg. 1986;95(1):104–6.CrossRefPubMed

Peters P, Repanos C, Earnshaw J, Stark P, Burmeister B, McGuire L, et al. Epithelial-myoepithelial carcinoma of the tongue base: a case for the case-report and review of the literature. Head Neck Oncol. 2010;2:4.PubMedCentralCrossRefPubMed

Corio RL, Sciubba JJ, Brannon RB, Batsakis JG. Epithelial-myoepithelial carcinoma of intercalated duct origin. A clinicopathologic and ultrastructural assessment of sixteen cases. Oral Surg Oral Med Oral Pathol. 1982;53(3):280–7.CrossRefPubMed

Simpson RH, Clarke TJ, Sarsfield PT, Gluckman PG. Epithelial-myoepithelial carcinoma of salivary glands. J Clin Pathol. 1991;44(5):419–23.PubMedCentralCrossRefPubMed

10.

Witterick IJ, Noyek AM, Chapnik JS, Heathcote JG, Bedard YC. Observations on the natural history of a parotid epithelial-myoepithelial carcinoma of intercalated ducts. J Otolaryngol. 1993;22(3):176–9.PubMed

11.

Hamper K, Brugmann M, Koppermann R, Caselitz J, Arps H, Askensten U, et al. Epithelial-myoepithelial duct carcinoma of salivary glands: a follow-up and cytophotometric study of 21 cases. J Oral Pathol Med. 1989;18(5):299–304.CrossRefPubMed

Title: Epithelial-myoepithelial carcinoma arising from the subglottis: a case report and review of the literature
Authors: Hun-Jae Oh
Nam-yong Do
Keun-Hong Kee
Jun-Hee Park
Publication date: 01-12-2016
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2016
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/s13256-016-0824-8

At a glance: The STEP trials

Springer Medicine

Epithelial-myoepithelial carcinoma arising from the subglottis: a case report and review of the literature

Abstract

Background

Case presentation

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Case presentation

Conclusions

Please log in to get access to this content

Other articles of this Issue 1/2016

IgG4-related disease presenting with an epidural inflammatory pseudotumor: a case report

Endometrial tuberculosis compounding polycystic ovary syndrome in a subfertile woman: a case report

Early-onset fetal growth restriction treated with the long-acting phosphodiesterase-5 inhibitor tadalafil: a case report

Worsening cholestasis and possible cefuroxime-induced liver injury following “successful” therapeutic endoscopic retrograde cholangiopancreatography for a distal common bile duct stone: a case report

Massive adrenal vein aneurysm mimicking an adrenal tumor in a patient with hemophilia A: a case report and review of the literature

Interaction of interferon alpha therapy with thyroid function tests in the management of hepatitis C: a case report