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The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

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Open Access 01-12-2021 | Epilepsy | Research

Predictive factors of epilepsy outcome in a sample of Egyptian pre-elderly and elderly population

Authors: Steven Emil Gerges, Mahmoud Hemeda El Rakawy, Naglaa Mohammed El Khayat, Yousry Abo Elnaga Abdelhamid, Ahmed Mohammed Hazzou, Hossam Mohammed Shokri, Mona Mokthar Wahid El din

Published in: The Egyptian Journal of Neurology, Psychiatry and Neurosurgery | Issue 1/2021

Abstract

Background

Elderly people with epilepsy are large, but neglected group. Data on the predictive factors for recurrent seizures in the elderly population are inconclusive or are not known for the majority of patients. This is especially true for the Egyptian population as no specific study was concluded to address this issue before.

Objectives

The aim of this study was to detect the predictive factors of epilepsy outcome in a sample of Egyptian aged population.

Materials and methods

A total of 100 patients aged 50 years or older with epilepsy diagnosed according to International League Against Epilepsy (ILAE) latest definition were included in the study and followed up for 6 months as regards seizure control. All participants were prospectively evaluated for epidemiological, clinical, radiological, electrodiagnostic, and laboratory data.

Results

The outcome was statistically significant affected in relation to absence of medical comorbidities (P = 0.037), seizure etiology (P = 0.007), history of status epilepticus (P < 0.001), MRI brain findings (P = 0.005), EEG changes (P < 0.001), Ca (P = 0.01), and Mg level (P = 0.046).

Conclusion

We conclude that aged Egyptian epileptic population with no medical comorbidities, normal MRI brain, or normal EEG can be predicted to have good outcome of their epilepsy while patients with post stroke epilepsy, abnormal MRI brain, and abnormal EEG, with low serum Ca or Mg level can be predicted to have poor outcome.

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Title: Predictive factors of epilepsy outcome in a sample of Egyptian pre-elderly and elderly population
Authors: Steven Emil Gerges
Mahmoud Hemeda El Rakawy
Naglaa Mohammed El Khayat
Yousry Abo Elnaga Abdelhamid
Ahmed Mohammed Hazzou
Hossam Mohammed Shokri
Mona Mokthar Wahid El din
Publication date: 01-12-2021
Publisher: Springer Berlin Heidelberg
Keywords: Epilepsy
Status Epilepticus
Published in: The Egyptian Journal of Neurology, Psychiatry and Neurosurgery / Issue 1/2021
Electronic ISSN: 1687-8329
DOI: https://doi.org/10.1186/s41983-021-00297-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Predictive factors of epilepsy outcome in a sample of Egyptian pre-elderly and elderly population

Abstract

Background

Objectives

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Objectives

Materials and methods

Results

Conclusion

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