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Published in: Journal of Neurology 10/2023

24-06-2023 | Epilepsy | Original Communication

Risk characteristics of alcohol and/or drug misuse in repeat emergency department attendees for seizures: a case–control study

Authors: Sarah Lennard, William Henley, Brendan McLean, Tom Thompson, Mark Jadav, Richard Laugharne, Rohit Shankar

Published in: Journal of Neurology | Issue 10/2023

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Abstract

Background

There is a bi-directional relationship between seizures and substance misuse, i.e., alcohol and recreational drugs. Seizures and substance misuse are recognised separately to influence increased emergency department (ED) admissions and early death. There is however no understanding of the cumulative influence of these matters on repeat ED attenders for seizures esp. as a third are likely to re-attend within the year. This case–control study compares the characteristics of people with substance misuse to those without substance misuse presenting recurrently with seizures to the ED.

Methods

From a single ED serving a rural population in the Southwest of England, data of all people presenting more than once with a seizure over a 4-year period were examined. The diagnosis of alcohol or drug misuse, deaths, demographic characteristics, and service use were captured.

Results

Of 450 repeat attenders, 95 had a recorded history of alcohol and/or drug problems. Those with substance misuse had double the mortality when adjusted for age and gender compared to those without. They were also more likely to be male, younger in age, have mental health issues, live in socially deprived neighborhoods, not take anti-seizure medications and not have had a specialist review in epilepsy services in the previous year. Nearly a quarter of those with addiction issues died in the 4-year period.

Discussion

Service provision for this vulnerable group may need to be modelled along different lines to traditional approaches, such as an assertive outreach community-based service as provided for chronic psychiatric and addiction management.
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Metadata
Title
Risk characteristics of alcohol and/or drug misuse in repeat emergency department attendees for seizures: a case–control study
Authors
Sarah Lennard
William Henley
Brendan McLean
Tom Thompson
Mark Jadav
Richard Laugharne
Rohit Shankar
Publication date
24-06-2023
Publisher
Springer Berlin Heidelberg
Published in
Journal of Neurology / Issue 10/2023
Print ISSN: 0340-5354
Electronic ISSN: 1432-1459
DOI
https://doi.org/10.1007/s00415-023-11833-9

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