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Critical Care
Published in: Critical Care 4/2013

01-08-2013 | Poster presentation

Epigenetic changes in dendritic cells in sepsis-associated immunosuppression

Authors: Raphael Molinaro, Papp Attila, Adriana Ribeiro Silva, Hugo Caire Castro-Faria-Neto, Claudia Farias Benjamim, Laszlo Nagy, Patrícia Torres Bozza

Published in: Critical Care | Special Issue 4/2013

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Excerpt

Sepsis is a systemic inflammatory response syndrome against infection, which can develop in sepsis-associated immunosuppression. Actually, several inflammatory dysfunctions have been described in dendritic cells (DCs), which could be responsible for impairing the immune response towards the secondary infection, although how these stable modifications maintain is still unknown. Our hypothesis is that DCs from post-septic mice have chromatin alteration and differential microRNA expression. …
Metadata
Title
Epigenetic changes in dendritic cells in sepsis-associated immunosuppression
Authors
Raphael Molinaro
Papp Attila
Adriana Ribeiro Silva
Hugo Caire Castro-Faria-Neto
Claudia Farias Benjamim
Laszlo Nagy
Patrícia Torres Bozza
Publication date
01-08-2013
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 4/2013
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc13001

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