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Published in: American Journal of Clinical Dermatology 3/2006

01-06-2006 | Original Research Article

Eosinophilic Folliculitis in HIV-Infected Women

Case Series and Review

Authors: Sareeta R.S. Parker, Douglas C. Parker, Dr Calvin O. McCall

Published in: American Journal of Clinical Dermatology | Issue 3/2006

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Abstract

Background and objective: Dermatologic conditions are often presenting signs of HIV infection and may be the sole cause of morbidity in patients who have otherwise stable HIV disease. Eosinophilic folliculitis is a pruritic, follicular eruption that typically manifests late in the course of HIV infection. Most published reports of eosinophilic folliculitis have been in HIV-infected men. In those reports, a characteristic truncal distribution was present, with involvement of the head, neck, and upper extremities commonly seen as well. The objective of this study was to better characterize the presentation of eosinophilic folliculitis in women.
Methods: We conducted a retrospective chart review of six HIV-seropositive women with eosinophilic folliculitis previously seen in our dermatology clinics. We also reviewed the literature for cases of eosinophilic folliculitis in women and for clinical and therapeutic aspects of the condition, particularly in women.
Results: In our case series, we found that eosinophilic folliculitis in women may predominantly affect the face and mimic acne excoriée. A review of the literature of HIV-associated eosinophilic folliculitis in women supports these findings. Regarding treatment, many therapies are available, but none is uniformly effective.
Conclusion: Given the dramatic rise in the incidence of HIV infection in women, who now represent nearly 50% of adults living worldwide with HIV/AIDS, a heightened awareness of HIV-related dermatoses in women is essential. HIV-associated eosinophilic folliculitis should be considered in the differential diagnosis of chronic, pruritic, papular facial eruptions in females.
Literature
1.
go back to reference Office of Communications and Public Liaison, US National Institute of Allergy and Infectious Diseases. Fact sheet: HIV infection in women [online]. Bethesda (MD): National Institutes of Health, US Department of Health and Human Services; 2004 May. Available from URL: http://www.niaid.nih.gov/factsheets/womenhiv.htm [Accessed 2006 May 8] Office of Communications and Public Liaison, US National Institute of Allergy and Infectious Diseases. Fact sheet: HIV infection in women [online]. Bethesda (MD): National Institutes of Health, US Department of Health and Human Services; 2004 May. Available from URL: http://​www.​niaid.​nih.​gov/​factsheets/​womenhiv.​htm [Accessed 2006 May 8]
2.
go back to reference Hayes BB, Hille RC, Goldberg LJ. Eosinophilic folliculitis in 2 HIV-positive women. Arch Dermatol. 2004; 140: 463–5PubMedCrossRef Hayes BB, Hille RC, Goldberg LJ. Eosinophilic folliculitis in 2 HIV-positive women. Arch Dermatol. 2004; 140: 463–5PubMedCrossRef
3.
go back to reference Stell I, Leen E. HIV-associated eosinophilic pustular folliculitis: the first case reported in a woman. J Am Acad Dermatol. 1996; 35: 106–8PubMedCrossRef Stell I, Leen E. HIV-associated eosinophilic pustular folliculitis: the first case reported in a woman. J Am Acad Dermatol. 1996; 35: 106–8PubMedCrossRef
4.
go back to reference Basarab T, Jones RR. HIV-associated eosinophilic folliculitis: case report and review of the literature. Br J Dermatol. 1996; 134: 499–503PubMedCrossRef Basarab T, Jones RR. HIV-associated eosinophilic folliculitis: case report and review of the literature. Br J Dermatol. 1996; 134: 499–503PubMedCrossRef
5.
go back to reference Teofoli P, Barbieri C, Pallotta S, et al. Pruritic eosinophilic papular eruption revealing HIV infection. Fur J Dermatol. 2002; 12: 600–2 Teofoli P, Barbieri C, Pallotta S, et al. Pruritic eosinophilic papular eruption revealing HIV infection. Fur J Dermatol. 2002; 12: 600–2
6.
go back to reference Ho MH, Chong LY, Ho TT. HIV-associated eosinophilic folliculitis in a Chinese woman: a case report and a survey in Hong Kong. Int J STD AIDS. 1998; 9: 489–93PubMedCrossRef Ho MH, Chong LY, Ho TT. HIV-associated eosinophilic folliculitis in a Chinese woman: a case report and a survey in Hong Kong. Int J STD AIDS. 1998; 9: 489–93PubMedCrossRef
7.
go back to reference Centers for Disease Control and Prevention. Revised classification system for HIV infection and expanded surveillance case definition for AIDS. MMWR Moth Mortal Wkly Rep. 1992 Dec 18; 41 (RR-17): 1 Centers for Disease Control and Prevention. Revised classification system for HIV infection and expanded surveillance case definition for AIDS. MMWR Moth Mortal Wkly Rep. 1992 Dec 18; 41 (RR-17): 1
8.
go back to reference Soeprono FF, Schinella RA. Eosinophilic pustular folliculitis in patients with acquired immunodeficiency syndrome. J Am Acad Dermatol 1986; 14: 1020–2PubMedCrossRef Soeprono FF, Schinella RA. Eosinophilic pustular folliculitis in patients with acquired immunodeficiency syndrome. J Am Acad Dermatol 1986; 14: 1020–2PubMedCrossRef
9.
go back to reference Ofuji S, Ogino A, Horio T, et al. Eosinophilic pustular folliculitis. Acta Derm Venereol (Stockh). 1970; 50: 195–203 Ofuji S, Ogino A, Horio T, et al. Eosinophilic pustular folliculitis. Acta Derm Venereol (Stockh). 1970; 50: 195–203
10.
go back to reference Takematsu H, Nakamura K, Igarashi M, et al. Eosinophilic pustular folliculitis: report of two cases with a review of the Japanese literature. Arch Dermatol. 1985; 121: 917–20PubMedCrossRef Takematsu H, Nakamura K, Igarashi M, et al. Eosinophilic pustular folliculitis: report of two cases with a review of the Japanese literature. Arch Dermatol. 1985; 121: 917–20PubMedCrossRef
11.
go back to reference Bull RH, Harland CA, Fallowfield ME, et al. Eosinophilic folliculitis: a self-limiting illness in patients being treated for haematological malignancy. Br J Dermatol. 1993; 129: 178–82PubMedCrossRef Bull RH, Harland CA, Fallowfield ME, et al. Eosinophilic folliculitis: a self-limiting illness in patients being treated for haematological malignancy. Br J Dermatol. 1993; 129: 178–82PubMedCrossRef
12.
go back to reference Evans TR, Mansi JL, Bull R, et al. Eosinophilic folliculitis occurring after bone marrow autograft in a patient with non-Hodgkin’s lymphoma. Cancer. 1994; 73: 2512–4PubMedCrossRef Evans TR, Mansi JL, Bull R, et al. Eosinophilic folliculitis occurring after bone marrow autograft in a patient with non-Hodgkin’s lymphoma. Cancer. 1994; 73: 2512–4PubMedCrossRef
13.
go back to reference Ramdial PK, Morar N, Dlova NC, et al. HIV-associated eosinophilic folliculitis in an infant. Am J Dermatopathol. 1999; 21: 241–6PubMedCrossRef Ramdial PK, Morar N, Dlova NC, et al. HIV-associated eosinophilic folliculitis in an infant. Am J Dermatopathol. 1999; 21: 241–6PubMedCrossRef
14.
go back to reference Fearfield LA, Francis N, Rowe A, et al. Itchy folliculitis and HIV infection. Br J Dermatol. 1999; 141: 3–11PubMedCrossRef Fearfield LA, Francis N, Rowe A, et al. Itchy folliculitis and HIV infection. Br J Dermatol. 1999; 141: 3–11PubMedCrossRef
15.
go back to reference Rosenthal D, LeBoit PE, Klumpp L, et al. Human immunodeficiency virus-associated eosinophilic folliculitis. Arch Dermatol. 1991; 127: 206–9PubMedCrossRef Rosenthal D, LeBoit PE, Klumpp L, et al. Human immunodeficiency virus-associated eosinophilic folliculitis. Arch Dermatol. 1991; 127: 206–9PubMedCrossRef
16.
go back to reference Majors MJ, Berger TG, Blauvelt A, et al. HIV-related eosinophilic folliculitis: a panel discussion. Semin Cutan Med Surg. 1997; 16: 219–23PubMedCrossRef Majors MJ, Berger TG, Blauvelt A, et al. HIV-related eosinophilic folliculitis: a panel discussion. Semin Cutan Med Surg. 1997; 16: 219–23PubMedCrossRef
17.
go back to reference McCalmont TH, Altemus D, Maurer T, et al. Eosinophilic folliculitis: the histologic spectrum. Am J Dermatopathol. 1995; 17: 439–46PubMedCrossRef McCalmont TH, Altemus D, Maurer T, et al. Eosinophilic folliculitis: the histologic spectrum. Am J Dermatopathol. 1995; 17: 439–46PubMedCrossRef
18.
go back to reference Simpson-Dent SL, Fearfield LA, Staughton RCD. HIV associated eosinophilic folliculitis: differential diagnosis and management. Sex Transm Infect. 1999; 75: 291–3PubMedCrossRef Simpson-Dent SL, Fearfield LA, Staughton RCD. HIV associated eosinophilic folliculitis: differential diagnosis and management. Sex Transm Infect. 1999; 75: 291–3PubMedCrossRef
19.
go back to reference Smith KJ, Skelton HG, Yeager J, et al. Metronidazole for eosinophilic pustular folliculitis in human immunodeficiency virus-type 1-positive patients. Arch Dermatol. 1995; 131: 1089–91PubMedCrossRef Smith KJ, Skelton HG, Yeager J, et al. Metronidazole for eosinophilic pustular folliculitis in human immunodeficiency virus-type 1-positive patients. Arch Dermatol. 1995; 131: 1089–91PubMedCrossRef
20.
go back to reference Buchness MR, Lim H, Hatcher VA, et al. Eosinophilic pustular folliculitis in the acquired immunodeficiency syndrome: treatment with ultraviolet B phototherapy. N Engl J Med. 1988; 318: 1183–6PubMedCrossRef Buchness MR, Lim H, Hatcher VA, et al. Eosinophilic pustular folliculitis in the acquired immunodeficiency syndrome: treatment with ultraviolet B phototherapy. N Engl J Med. 1988; 318: 1183–6PubMedCrossRef
21.
go back to reference Lim H, Vallurupalli S, Meola T, et al. UVB phototherapy is an effective treatment for pruritus in patients with HIV. J Am Acad Dermatol. 1997; 37: 414–7PubMedCrossRef Lim H, Vallurupalli S, Meola T, et al. UVB phototherapy is an effective treatment for pruritus in patients with HIV. J Am Acad Dermatol. 1997; 37: 414–7PubMedCrossRef
22.
go back to reference Berger TG, Heon V, King C, et al. Itraconazole therapy for human immunodeficiency virus-associated eosinophilic folliculitis. Arch Dermatol. 1995; 131: 358–60PubMedCrossRef Berger TG, Heon V, King C, et al. Itraconazole therapy for human immunodeficiency virus-associated eosinophilic folliculitis. Arch Dermatol. 1995; 131: 358–60PubMedCrossRef
23.
go back to reference Otley CC, Avram MR, Johnson RA. Isotretinoin treatment of human immunodeficiency virus-associated eosinophilic folliculitis. Arch Dermatol. 1995; 131: 1047–50PubMedCrossRef Otley CC, Avram MR, Johnson RA. Isotretinoin treatment of human immunodeficiency virus-associated eosinophilic folliculitis. Arch Dermatol. 1995; 131: 1047–50PubMedCrossRef
24.
go back to reference Blauvelt A, Plott RT, Spooner K, et al. Eosinophilic folliculitis associated with the acquired immunodeficiency syndrome responds well to permethrin. Arch Dermatol. 1995; 131: 360–1PubMedCrossRef Blauvelt A, Plott RT, Spooner K, et al. Eosinophilic folliculitis associated with the acquired immunodeficiency syndrome responds well to permethrin. Arch Dermatol. 1995; 131: 360–1PubMedCrossRef
25.
go back to reference Toutous-Trellu L, Abraham S, Pechere M, et al. Topical tacrolimus for effective treatment of eosinophilic folliculitis associated with human immunodeficiency virus infection. Arch Dermatol. 2005; 141: 1203–8PubMedCrossRef Toutous-Trellu L, Abraham S, Pechere M, et al. Topical tacrolimus for effective treatment of eosinophilic folliculitis associated with human immunodeficiency virus infection. Arch Dermatol. 2005; 141: 1203–8PubMedCrossRef
Metadata
Title
Eosinophilic Folliculitis in HIV-Infected Women
Case Series and Review
Authors
Sareeta R.S. Parker
Douglas C. Parker
Dr Calvin O. McCall
Publication date
01-06-2006
Publisher
Springer International Publishing
Published in
American Journal of Clinical Dermatology / Issue 3/2006
Print ISSN: 1175-0561
Electronic ISSN: 1179-1888
DOI
https://doi.org/10.2165/00128071-200607030-00006

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