Skip to main content
Top
Published in: Indian Journal of Gastroenterology 2/2020

01-04-2020 | Eosinophilic Esophagitis | Technical Notes

Chronic vomiting in children: Etiology, diagnosis, and management

Author: Aathira Ravindranath

Published in: Indian Journal of Gastroenterology | Issue 2/2020

Login to get access

Excerpt

Vomiting involves forceful expulsion of gastric contents through the mouth (may be associated with nausea and retching). Nausea is a subjective feeling of unpleasantness accompanied by pallor, hypersalivation, and anorexia. Retching encompasses spasmodic respiratory movements, and contraction of abdominal muscles against a closed glottis without actually throwing out gastric contents [1]. Regurgitation is the passive effortless movement of gastric contents into the mouth without abdominal wall contractions. Rumination involves effortless bringing up of recently ingested food through a voluntary increase in abdominal pressure, chewing, and sometimes re-swallowing [2]. Though definitions make our understanding easier, analyzing the symptoms in a child is a challenge in itself and a clear distinction between the above conditions cannot be made and the parents often put everything in the basket of “vomiting.” Thus, tweezing out the underlying cause requires thorough history taking from the child and the parents. The next question that arises with respect to children is the definition of chronic vomiting. Though the ROME IV criteria define the duration of chronic nausea and vomiting in children as 2 months, a more practical cut-off would be to take 4 weeks so that evaluation is not delayed [3]. …
Literature
1.
go back to reference Lacy BE, Parkman HP, Camilleri M. Chronic nausea and vomiting: evaluation and treatment. Am J Gastroenterol. 2018;113:647–59.CrossRef Lacy BE, Parkman HP, Camilleri M. Chronic nausea and vomiting: evaluation and treatment. Am J Gastroenterol. 2018;113:647–59.CrossRef
2.
go back to reference Stanghellini V, Chan FK, Hasler WL, et al. Gastroduodenal disorders. Gastroenterology. 2016;150:1380–92. Stanghellini V, Chan FK, Hasler WL, et al. Gastroduodenal disorders. Gastroenterology. 2016;150:1380–92.
3.
go back to reference Hyams JS, Di Lorenzo C, Saps M, Shulman RJ, Staiano A, van Tilburg M. Functional disorders: children and adolescents. Gastroenterology. 2016;S0016–5085:00181–5. Hyams JS, Di Lorenzo C, Saps M, Shulman RJ, Staiano A, van Tilburg M. Functional disorders: children and adolescents. Gastroenterology. 2016;S0016–5085:00181–5.
5.
go back to reference Nelson SP, Chen EH, Syniar GM, Christoffel KK. Prevalence of symptomatic gastroesophageal reflux during infancy. A pediatric practice-based survey, pediatric practice research group. Arch Pediatr Adolesc Med. 1997;151:569–72.CrossRef Nelson SP, Chen EH, Syniar GM, Christoffel KK. Prevalence of symptomatic gastroesophageal reflux during infancy. A pediatric practice-based survey, pediatric practice research group. Arch Pediatr Adolesc Med. 1997;151:569–72.CrossRef
6.
go back to reference Hegar B, Dewanti NR, Kadim M, Alatas S, Firmansyah A, Vandenplas Y. Natural evolution of regurgitation in healthy infants. Acta Paediatr. 2009;98:1189–93.CrossRef Hegar B, Dewanti NR, Kadim M,  Alatas S, Firmansyah A, Vandenplas Y.  Natural evolution of regurgitation in healthy infants. Acta Paediatr. 2009;98:1189–93.CrossRef
7.
go back to reference Nielsen RG, Bindslev-Jensen C, Kruse-Andersen S, Husby S. Severe gastroesophageal reflux disease and cow milk hypersensitivity in infants and children: disease association and evaluation of a new challenge procedure. J Pediatr Gastroenterol Nutr. 2004;39:383–91.CrossRef Nielsen RG, Bindslev-Jensen C, Kruse-Andersen S, Husby S. Severe gastroesophageal reflux disease and cow milk hypersensitivity in infants and children: disease association and evaluation of a new challenge procedure. J Pediatr Gastroenterol Nutr. 2004;39:383–91.CrossRef
8.
go back to reference Rosen R, Vandenplas Y, Singendonk M, et al. Pediatric gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. 2018;66:516–54.CrossRef Rosen R, Vandenplas Y, Singendonk M, et al. Pediatric gastroesophageal Reflux Clinical Practice Guidelines: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. 2018;66:516–54.CrossRef
9.
go back to reference Kapel RC, Miller JK, Torres C, Aksoy S, Lash R, Katzka DA. Eosinophilic esophagitis: a prevalent disease in the United States that affects all age groups. Gastroenterology. 2008;134:1316–21.CrossRef Kapel RC, Miller JK, Torres C, Aksoy S, Lash R, Katzka DA. Eosinophilic esophagitis: a prevalent disease in the United States that affects all age groups. Gastroenterology. 2008;134:1316–21.CrossRef
10.
go back to reference Zhao L, Feng S, Wu P, Lai XH, Lv C, Chen G. Clinical characteristics and surgical outcome in children with intussusceptions secondary to pathologic lead points: retrospective study in a single institution. Pediatr Surg Int. 2019;35:807–11.CrossRef Zhao L, Feng S, Wu P,  Lai XH, Lv C, Chen G. Clinical characteristics and surgical outcome in children with intussusceptions secondary to pathologic lead points: retrospective study in a single institution. Pediatr Surg Int. 2019;35:807–11.CrossRef
11.
go back to reference Singh SK, Srivastava A, Kumari N, Poddar U, Yachha SK, Pandey CM. Differentiation between Crohn disease and intestinal tuberculosis in children. J Pediatr Gastroenterol Nutr. 2018;66:e6–e11.CrossRef Singh SK, Srivastava A, Kumari N,  Poddar U, Yachha SK, Pandey CM. Differentiation between Crohn disease and intestinal tuberculosis in children. J Pediatr Gastroenterol Nutr. 2018;66:e6–e11.CrossRef
12.
go back to reference Hartmann AS, Poulain T, Vogel M, Hiemisch A, Kiess W, Hilbert A. Prevalence of pica and rumination behaviors in German children aged 7-14 and their associations with feeding, eating, and general psychopathology: a population-based study. Eur Child Adolesc Psychiatry. 2018;27:1499–508.CrossRef Hartmann AS, Poulain T, Vogel M, Hiemisch A, Kiess W, Hilbert A. Prevalence of pica and rumination behaviors in German children aged 7-14 and their associations with feeding, eating, and general psychopathology: a population-based study. Eur Child Adolesc Psychiatry. 2018;27:1499–508.CrossRef
13.
go back to reference Stocco C, Pilotto C, Passone E, et al. Presentation and symptom interval in children with central nervous system tumors. A single-center experience. Childs Nerv Syst. 2017;33:2109–16.CrossRef Stocco C, Pilotto C, Passone E, et al. Presentation and symptom interval in children with central nervous system tumors. A single-center experience. Childs Nerv Syst. 2017;33:2109–16.CrossRef
14.
go back to reference Bhatia V, Deswal S, Seth S, Kapoor A, Sibal A, Gopalan S. Prevalence of functional gastrointestinal disorders among adolescents in Delhi based on Rome III criteria: a school-based survey. Indian J Gastroenterol. 2016;35:294–8.CrossRef Bhatia V, Deswal S, Seth S, Kapoor A, Sibal A, Gopalan S. Prevalence of functional gastrointestinal disorders among adolescents in Delhi based on Rome III criteria: a school-based survey. Indian J Gastroenterol. 2016;35:294–8.CrossRef
15.
go back to reference Li BU, Lefevre F, Chelimsky GG, et al. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition consensus statement on the diagnosis and management of cyclic vomiting syndrome. J Pediatr Gastroenterol Nutr. 2008;47:379–93.CrossRef Li BU, Lefevre F, Chelimsky GG, et al. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition consensus statement on the diagnosis and management of cyclic vomiting syndrome. J Pediatr Gastroenterol Nutr. 2008;47:379–93.CrossRef
16.
go back to reference Bakal U, Sarac M, Aydin M, Tartar T, Kazez A. Recent changes in the features of hypertrophic pyloric stenosis. Pediatr Int. 2016;58:369–71.CrossRef Bakal U, Sarac M, Aydin M, Tartar T, Kazez A. Recent changes in the features of hypertrophic pyloric stenosis. Pediatr Int. 2016;58:369–71.CrossRef
17.
go back to reference Costa Dias S, Swinson S, Torrão H, et al. Hypertrophic pyloric stenosis: tips and tricks for ultrasound diagnosis. Insights Imaging. 2012;3:247–50.CrossRef Costa Dias S, Swinson S, Torrão H, et al. Hypertrophic pyloric stenosis: tips and tricks for ultrasound diagnosis. Insights Imaging. 2012;3:247–50.CrossRef
18.
go back to reference Sangüesa NC, Salvador LR, Palacios CE, Picó Aliaga S, Ibañez PV. Enteric duplication cysts in children: varied presentations, varied imaging findings. Insights Imaging. 2018;9:1097–106.CrossRef Sangüesa NC, Salvador LR, Palacios CE, Picó Aliaga S, Ibañez PV. Enteric duplication cysts in children: varied presentations, varied imaging findings. Insights Imaging. 2018;9:1097–106.CrossRef
19.
go back to reference Bartocci M, Fabrizi G, Valente I, Manzoni C, Speca S, Bonomo L. Intussusception in childhood: role of sonography on diagnosis and treatment. J Ultrasound. 2014;18:205–11.CrossRef Bartocci M, Fabrizi G, Valente I, Manzoni C, Speca S, Bonomo L. Intussusception in childhood: role of sonography on diagnosis and treatment. J Ultrasound. 2014;18:205–11.CrossRef
20.
go back to reference Thomson M, Sharma S. Diagnostic yield of upper and lower gastrointestinal endoscopies in children in a tertiary Centre. J Pediatr Gastroenterol Nutr. 2017;64:903–6.CrossRef Thomson M, Sharma S. Diagnostic yield of upper and lower gastrointestinal endoscopies in children in a tertiary Centre. J Pediatr Gastroenterol Nutr. 2017;64:903–6.CrossRef
21.
go back to reference El-Mouzan MI, Al-Mofleh IA, Abdullah AM, Al-Rashed RS. Indications and yield of upper gastrointestinal endoscopy in children. Saudi Med J. 2004;25:1223–5.PubMed El-Mouzan MI, Al-Mofleh IA, Abdullah AM, Al-Rashed RS. Indications and yield of upper gastrointestinal endoscopy in children. Saudi Med J. 2004;25:1223–5.PubMed
22.
go back to reference Muir AB, Merves J, Liacouras CA. Role of endoscopy in diagnosis and management of pediatric eosinophilic esophagitis. Gastrointest Endosc Clin N Am. 2016;26:187–200.CrossRef Muir AB, Merves J, Liacouras CA. Role of endoscopy in diagnosis and management of pediatric eosinophilic esophagitis. Gastrointest Endosc Clin N Am. 2016;26:187–200.CrossRef
24.
go back to reference Singendonk MM, Kritas S, Cock C, et al. Applying the Chicago Classification criteria of esophageal motility to a pediatric cohort: effects of patient age and size. Neurogastroenterol Motil. 2014;26:1333–41.CrossRef Singendonk MM, Kritas S, Cock C, et al. Applying the Chicago Classification criteria of esophageal motility to a pediatric cohort: effects of patient age and size. Neurogastroenterol Motil. 2014;26:1333–41.CrossRef
25.
go back to reference Koletzko S, Niggemann B, Arato A, et al. Diagnostic approach and management of cow’s-milk protein allergy in infants and children: ESPGHAN GI Committee practical guidelines. J Pediatr Gastroenterol Nutr. 2012;55:221–9.CrossRef Koletzko S, Niggemann B, Arato A, et al. Diagnostic approach and management of cow’s-milk protein allergy in infants and children: ESPGHAN GI Committee practical guidelines. J Pediatr Gastroenterol Nutr. 2012;55:221–9.CrossRef
26.
go back to reference Kagalwalla AF, Sentongo TA, Ritz S, et al. Effect of six-food elimination diet on clinical and histologic outcomes in eosinophilic esophagitis. Clin Gastroenterol Hepatol. 2006;4:1097–102.CrossRef Kagalwalla AF, Sentongo TA, Ritz S, et al. Effect of six-food elimination diet on clinical and histologic outcomes in eosinophilic esophagitis. Clin Gastroenterol Hepatol. 2006;4:1097–102.CrossRef
27.
go back to reference Aceves SS, Bastian JF, Newbury RO, Dohil R. Oral viscous budesonide: a potential new therapy for eosinophilic esophagitis in children. Am J Gastroenterol. 2007;102:2271–9.CrossRef Aceves SS, Bastian JF, Newbury RO, Dohil R. Oral viscous budesonide: a potential new therapy for eosinophilic esophagitis in children. Am J Gastroenterol. 2007;102:2271–9.CrossRef
28.
go back to reference Sinagra E, Raimondo D, Albano D, et al. Superior mesenteric artery syndrome: clinical, endoscopic, and radiological findings. Gastroenterol Res Pract. 2018;27:1937416. Sinagra E, Raimondo D, Albano D, et al. Superior mesenteric artery syndrome: clinical, endoscopic, and radiological findings. Gastroenterol Res Pract. 2018;27:1937416.
29.
go back to reference Lee Y, Brar K, Doumouras AG, Hong D. Peroral endoscopic myotomy (POEM) for the treatment of pediatric achalasia: a systematic review and meta-analysis. Surg Endosc. 2019;33:1710–20.CrossRef Lee Y, Brar K, Doumouras AG, Hong D. Peroral endoscopic myotomy (POEM) for the treatment of pediatric achalasia: a systematic review and meta-analysis. Surg Endosc. 2019;33:1710–20.CrossRef
30.
go back to reference Murray HB, Juarascio AS, Di Lorenzo C, Drossman DA, Thomas JJ. Diagnosis and treatment of rumination syndrome: a critical review. Am J Gastroenterol. 2019;114:562–78.CrossRef Murray HB, Juarascio AS, Di Lorenzo C, Drossman DA, Thomas JJ. Diagnosis and treatment of rumination syndrome: a critical review. Am J Gastroenterol. 2019;114:562–78.CrossRef
31.
go back to reference Fitzpatrick E, Bourke B, Drumm B, Rowland M. Outcome for children with cyclical vomiting syndrome. Arch Dis Child. 2007;92:1001–4.CrossRef Fitzpatrick E, Bourke B, Drumm B, Rowland M. Outcome for children with cyclical vomiting syndrome. Arch Dis Child. 2007;92:1001–4.CrossRef
32.
go back to reference Setia A, Nair P, Cheng SX. Gastric electrical stimulation: an emerging therapy for children with intractable gastroparesis. World J Gastroenterol. 2019;25:6880–9.CrossRef Setia A, Nair P, Cheng SX. Gastric electrical stimulation: an emerging therapy for children with intractable gastroparesis. World J Gastroenterol. 2019;25:6880–9.CrossRef
Metadata
Title
Chronic vomiting in children: Etiology, diagnosis, and management
Author
Aathira Ravindranath
Publication date
01-04-2020
Publisher
Springer India
Published in
Indian Journal of Gastroenterology / Issue 2/2020
Print ISSN: 0254-8860
Electronic ISSN: 0975-0711
DOI
https://doi.org/10.1007/s12664-020-01035-w

Other articles of this Issue 2/2020

Indian Journal of Gastroenterology 2/2020 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine