Skip to main content
Top
Published in: La radiologia medica 10/2022

Open Access 01-10-2022 | Enthesopathy | Musculoskeletal Radiology

Prevalence and characteristics of diffuse idiopathic skeletal hyperostosis (DISH) in Italy

Authors: Jacopo Ciaffi, Elena Borlandelli, Gaia Visani, Giancarlo Facchini, Marco Miceli, Piero Ruscitti, Paola Cipriani, Roberto Giacomelli, Francesco Ursini

Published in: La radiologia medica | Issue 10/2022

Login to get access

Abstract

Purpose

Diffuse idiopathic skeletal hyperostosis (DISH) is a benign condition characterized by ossification of the spine and prominent enthesopathies. Highly heterogeneous epidemiological figures have been reported in the literature, while in Italy the largest study has been conducted in 1992. The aim of our research is to contribute updated information about prevalence of DISH in Italy and to describe the clinical and radiographic characteristics associated with the disorder.

Material and methods

A retrospective review of lumbosacral spine, thoracic spine and pelvis radiographs was performed. Consecutive patients visiting the emergency department of our Institution over 3 years were enrolled. Presence of DISH was evaluated applying the Resnick and Niwayama criteria. Clinical and radiological features were also assessed.

Results

We included 1012 individuals (60.6% women), and DISH was present in 130 cases. The overall prevalence of DISH was 12.8% (95% CI 10.8–15.1), with higher figures in the male sample (16.8%) than in females (10.3%). In binary logistic regression adjusted for age, BMI (OR 1.50, p < 0.001) diabetes (OR 1.85, p = 0.003), hypertension (OR 2.04, p = 0.007) ischiopubic enthesopathy (OR 7.08, p < 0.001), iliac crest enthesopathy (OR 4.63, p < 0.001) and greater trochanter enthesopathy (OR 3.51, p < 0.001), were significantly associated with the condition.

Conclusion

The prevalence of DISH observed in our study is consistent with previous literature, and we confirm that the disorder is more frequently retrieved in men and that it is associated with the presence of metabolic disorders and pelvic enthesopathy. Knowledge about the epidemiology and characteristics of DISH is needed to properly identify the condition.
Literature
4.
11.
go back to reference Scutellari PN, Orzincolo C, Princivalle M, Franceschini F (1992) Diffuse idiopathic skeletal hyperostosis. Review of diagnostic criteria and analysis of 915 cases. Radiol Med 83(6):729–36. Scutellari PN, Orzincolo C, Princivalle M, Franceschini F (1992) Diffuse idiopathic skeletal hyperostosis. Review of diagnostic criteria and analysis of 915 cases. Radiol Med 83(6):729–36.
13.
go back to reference Pappone N, Lubrano E, Esposito-del Puente A, D’Angelo S, Di Girolamo C, Del Puente A (2005) Prevalence of diffuse idiopathic skeletal hyperostosis in a female Italian population. Clin Exp Rheumatol 23(1):123–124PubMed Pappone N, Lubrano E, Esposito-del Puente A, D’Angelo S, Di Girolamo C, Del Puente A (2005) Prevalence of diffuse idiopathic skeletal hyperostosis in a female Italian population. Clin Exp Rheumatol 23(1):123–124PubMed
34.
go back to reference Coaccioli S, Fatati G, Di Cato L, Marioli D, Patucchi E, Pizzuti C et al (2000) Diffuse idiopathic skeletal hyperostosis in diabetes mellitus, impaired glucose tolerance and obesity. Panminerva Med 42(4):247–251PubMed Coaccioli S, Fatati G, Di Cato L, Marioli D, Patucchi E, Pizzuti C et al (2000) Diffuse idiopathic skeletal hyperostosis in diabetes mellitus, impaired glucose tolerance and obesity. Panminerva Med 42(4):247–251PubMed
47.
go back to reference Denko CW, Boja B, Moskowitz RW (1994) Growth promoting peptides in osteoarthritis and diffuse idiopathic skeletal hyperostosis–insulin, insulin-like growth factor-I, growth hormone. J Rheumatol 21(9):1725–1730PubMed Denko CW, Boja B, Moskowitz RW (1994) Growth promoting peptides in osteoarthritis and diffuse idiopathic skeletal hyperostosis–insulin, insulin-like growth factor-I, growth hormone. J Rheumatol 21(9):1725–1730PubMed
54.
go back to reference Ursini F, D’Angelo S, Russo E, Arturi F, D’Antona L, Bruno C et al (2017) Serum complement C3 strongly correlates with whole-body insulin sensitivity in rheumatoid arthritis. Clin Exp Rheumatol 35(1):18–23PubMed Ursini F, D’Angelo S, Russo E, Arturi F, D’Antona L, Bruno C et al (2017) Serum complement C3 strongly correlates with whole-body insulin sensitivity in rheumatoid arthritis. Clin Exp Rheumatol 35(1):18–23PubMed
59.
go back to reference La Paglia E, Zawaideh JP, Lucii G, Mazzei MA (2019) MRI of the axial skeleton: differentiating non-inflammatory diseases and axial spondyloarthritis: a review of current concepts and applications : Special issue on “musculoskeletal imaging of the inflammatory and degenerative joints: current status and perspectives.” Radiol Med 124(11):1151–1166. https://doi.org/10.1007/s11547-019-01045-5CrossRefPubMed La Paglia E, Zawaideh JP, Lucii G, Mazzei MA (2019) MRI of the axial skeleton: differentiating non-inflammatory diseases and axial spondyloarthritis: a review of current concepts and applications : Special issue on “musculoskeletal imaging of the inflammatory and degenerative joints: current status and perspectives.” Radiol Med 124(11):1151–1166. https://​doi.​org/​10.​1007/​s11547-019-01045-5CrossRefPubMed
Metadata
Title
Prevalence and characteristics of diffuse idiopathic skeletal hyperostosis (DISH) in Italy
Authors
Jacopo Ciaffi
Elena Borlandelli
Gaia Visani
Giancarlo Facchini
Marco Miceli
Piero Ruscitti
Paola Cipriani
Roberto Giacomelli
Francesco Ursini
Publication date
01-10-2022
Publisher
Springer Milan
Published in
La radiologia medica / Issue 10/2022
Print ISSN: 0033-8362
Electronic ISSN: 1826-6983
DOI
https://doi.org/10.1007/s11547-022-01545-x

Other articles of this Issue 10/2022

La radiologia medica 10/2022 Go to the issue