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01-03-2017 | Brief Communication

Enrofloxacin stimulates cell death in several tissues of vannamei shrimp (Litopenaeus vannamei)

Authors: Maftuch, Khadijah Aziz, Deaniza Eslfitri, Ellana Sanoesi, Asep A. Prihanto

Published in: Comparative Clinical Pathology | Issue 2/2017

Abstract

The aim of this research was to investigate the effect of enrofloxacin on vannamei shrimp (Litopenaeus vanammei) by measuring its accumulation and withdrawal time, in addition to its histopathological effects. The effect of enrofloxacin on the cells of vannamei shrimp has not yet been reported. The enrofloxacin levels were analysed by enzyme-linked immunosorbent assay (ELISA), and several tissues and organs, including the hepatopancreas, gills and muscles, were histopathologically analysed. Regarding the withdrawal time from shrimp tissue, the optimum enrofloxacin dose is 26.06 ± 13.67 μg/kg. The greatest enrofloxacin-induced damage was observed in the hepatopancreas, in which necrosis, aggregate transformed microvilli, atrophy, inflammatory cell infiltration and plasma leaking from blood vessels were observed. In addition, necrosis was found in the muscle tissue. However, no damage was found in the gills, and enrofloxacin did not affect the lymphoid organ, midgut caeca or gastric organ.

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Title: Enrofloxacin stimulates cell death in several tissues of vannamei shrimp (Litopenaeus vannamei)
Authors: Maftuch
Khadijah Aziz
Deaniza Eslfitri
Ellana Sanoesi
Asep A. Prihanto
Publication date: 01-03-2017
Publisher: Springer London
Published in: Comparative Clinical Pathology / Issue 2/2017
Print ISSN: 1618-5641
Electronic ISSN: 1618-565X
DOI: https://doi.org/10.1007/s00580-016-2384-0

At a glance: The STEP trials

Springer Medicine

Enrofloxacin stimulates cell death in several tissues of vannamei shrimp (Litopenaeus vannamei)

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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