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01-04-2015 | Editorial Commentary

Enhancing the Management of Acute Asthma in Children: Do We Have the Evidence?

Author: Joseph L. Mathew

Published in: Indian Journal of Pediatrics | Issue 4/2015

Excerpt

Some months back, Indian Journal of Pediatrics suggested ways to enhance the management of persistent asthma in children, to improve outcomes [1]. This issue of the Journal includes two well-designed studies [2, 3], exploring the potential for improving the management (and outcomes) of acute asthma. Arulparithi et al. describe a randomized trial comparing the efficacy of inhaled Budesonide vs. oral Prednisolone in a small cohort of children with mild to moderate severity acute asthma [2]; and Wang et al. investigated the efficacy of inhaled magnesium on provoked bronchospasm in another cohort of children [3]. …

Mathew JL. Effective management of childhood asthma: pediatricians need to go the extra mile! Indian J Pediatr. 2013;80:536–7.CrossRefPubMed

Arulparithi CS, Babu TA, Ravichandran C, Santhanam I, Sathyamurthi B, Parivathini S, et al. Efficacy of nebulised budesonide versus oral prednisolone in acute severe asthma. Indian J Pediatr. 2014. doi:10.1007/s12098-014-1498-0.PubMed

Wang H, Xiong Y, Gong C, Yin L, Yan L, Yuan X, et al. Effect of inhaled magnesium sulfate on bronchial hyperresponsiveness. Indian J Pediatr. 2014. doi:10.1007/s12098-014-1476-6.

Devidayal, Singhi S, Kumar L, Jayshree M. Efficacy of nebulized budesonide compared to oral prednisolone in acute bronchial asthma. Acta Paediatr. 1999;88:835–40.CrossRefPubMed

Edmonds ML, Milan SJ, Camargo CA Jr, Pollack CV, Rowe BH. Early use of inhaled corticosteroids in the emergency department treatment of acute asthma. Cochrane Database Syst Rev. 2012;12:CD002308.

Edmonds ML, Camargo CA Jr , Pollack CV Jr, Rowe BH. Early use of inhaled corticosteroids in the emergency department treatment of acute asthma. Cochrane Database Syst Rev. 2003;3:CD002308.

Edmonds ML, Camargo CA Jr, Pollack CV Jr, Rowe BH. The effectiveness of inhaled corticosteroids in the emergency department treatment of acute asthma: a meta-analysis. Ann Emerg Med. 2002;40:145–54.

Edmonds ML, Camargo CA, Pollack CV, Rowe BH. Early use of inhaled corticosteroids in the emergency department treatment of acute asthma. Cochrane Database Syst Rev. 2001;1:CD002308.PubMed

Edmonds ML, Camargo CA, Pollack CV, Rowe BH. Early use of inhaled corticosteroids in the emergency department treatment of acute asthma. Cochrane Database Syst Rev. 2000;3:CD002308.PubMed

10.

No authors listed. British guideline on the management of asthma. Available from: https://www.brit-thoracic.org.uk/document-library/clinical-information/asthma/btssign-asthma-guideline-2014/ Accessed on: 12 November 2014

11.

No authors listed. Pocket guide for asthma management and prevention (for children 5 years and younger) Available from: http://www.ginasthma.org/local/uploads/files/GINA_Pediatric_Pocket_2014.pdf. Accessed on: 12 November 2014.

12.

Kling S, Zar HZ, Levin ME, Green RJ, Jeena PM, Risenga SM, et al; For the South African Childhood Asthma Working Group (SACAWG). Guideline for the management of acute asthma in children: 2013 update. Available from: http://www.samj.org.za/index.php/samj/article/view/6658/4940. Accessed on 12 November 2014.

13.

Powell C, Dwan K, Milan SJ, Beasley R, Hughes R, Knopp-Sihota JA, et al. Inhaled magnesium sulfate in the treatment of acute asthma. Cochrane Database Syst Rev. 2012;12:CD003898.PubMed

14.

Goodacre S, Cohen J, Bradburn M, Stevens J, Gray A, Benger J, et al; 3 Mg Research Team. The 3 Mg trial: a randomised controlled trial of intravenous or nebulized magnesium sulphate versus placebo in adults with acute severe asthma. Health Technol Assess. 2014;18:1–168.

15.

Shan Z, Rong Y, Yang W, Wang D, Yao P, Xie J, et al. Intravenous and nebulized magnesium sulfate for treating acute asthma in adults and children: a systematic review and meta-analysis. Respir Med. 2013;107:321–30.CrossRefPubMed

16.

Powell CV. The role of magnesium sulfate in acute asthma: does route of administration make a difference? Curr Opin Pulm Med. 2014;20:103–8.CrossRefPubMed

Title: Enhancing the Management of Acute Asthma in Children: Do We Have the Evidence?
Author: Joseph L. Mathew
Publication date: 01-04-2015
Publisher: Springer India
Published in: Indian Journal of Pediatrics / Issue 4/2015
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI: https://doi.org/10.1007/s12098-014-1673-3

At a glance: The STEP trials

Springer Medicine

Enhancing the Management of Acute Asthma in Children: Do We Have the Evidence?

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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