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01-03-2018 | Case Report

Enhancement of multiple cranial and spinal nerves in vanishing white matter: expanding the differential diagnosis

Authors: Thomas Jose Eluvathingal Muttikkal, Denia Ramirez Montealegre, Julie Ann Matsumoto

Published in: Pediatric Radiology | Issue 3/2018

Abstract

Abnormal cranial or spinal nerve contrast enhancement on MRI in cases of suspected pediatric leukodystrophy is recognized as an important clue to the diagnosis of either metachromatic leukodystrophy or globoid cell leukodystrophy (Krabbe disease). We report a case of genetically confirmed childhood vanishing white matter with enhancement of multiple cranial and spinal nerves in addition to the more typical intracranial findings. This case expands the limited differential diagnosis of cranial nerve or spinal nerve enhancement in cases of suspected leukodystrophy and may aid in more efficient work-up and earlier diagnosis of vanishing white matter.

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Title: Enhancement of multiple cranial and spinal nerves in vanishing white matter: expanding the differential diagnosis
Authors: Thomas Jose Eluvathingal Muttikkal
Denia Ramirez Montealegre
Julie Ann Matsumoto
Publication date: 01-03-2018
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Radiology / Issue 3/2018
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-017-3997-4

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Enhancement of multiple cranial and spinal nerves in vanishing white matter: expanding the differential diagnosis

Abstract

Keynote webinar | Spotlight on medication adherence

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Abstract

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