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Published in:

01-09-2011 | Review Article

Enhanced endoscopic imaging and gastroesophageal reflux disease

Authors: Rupa Banerjee, D. Nageshwar Reddy

Published in: Indian Journal of Gastroenterology | Issue 5/2011

Abstract

Gastroesophageal reflux disease (GERD) and GERD-related symptoms are common, and affect 25% to 30% of the general population. Upper gastrointestinal endoscopy of the esophagus has been the most widely used modality for the diagnosis and grading of reflux disease. Endoscopic imaging today has evolved beyond the confines of routine white light endoscopy (WLE) to advanced optical imaging with a precise and real time endoscopic diagnosis. These technological advances have helped circumvent the limitation of WLE in reflux disease by a) improved detection of subtle irregularities, b) characterization of anomalies, and c) possible optical biopsies providing real-time diagnosis. This review attempts to define the current status of these newer technologies vis-a-vis the diagnosis and management of gastroesophageal reflux disease.

Dent J, El-Serag HB, Wallander MA, et al. Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut. 2005;54:710–7.PubMedCrossRef

Bhatia SJ, Reddy DN, Ghoshal UC, et al. Epidemiology and symptom profile of gastroesophageal reflux in the Indian population: report of the Indian Society of Gastroenterology Task Force. Indian J Gastroenterol. 2011;30:118–27.

Bruley des Varannes S, Marek L, Humeau B, et al. Gastroesophageal reflux disease in primary care: prevalence, epidemiology and quality of life of patients. Gastroenterol Clin Biol. 2006;30:364–70.PubMedCrossRef

Wahlqvist P, Karlsson M, Johnson D, et al. Relationship between symptom load of gastro-oesophageal reflux disease and health-related quality of life, work productivity, resource utilization and concomitant diseases: survey of a US cohort. Aliment Pharmacol Ther. 2008;27:960–70.PubMedCrossRef

Dent J, Brun J, Fendrick AM, et al. An evidence-based appraisal of reflux disease management: the Genval workshop report. Gut. 1999;44 Suppl 2:S1–S16.CrossRef

Falk GW, Fennerty BF, Rothstein RI. AGA institute technical review on the use of endoscopic therapy for gastroesophageal reflux disease. Gastroenterology. 2006;131:1315–36.PubMedCrossRef

Wani S, Sharma P. Changing the “contrast” in GERD. Gastrointest Endosc. 2007;66:237–9.PubMedCrossRef

Nakamura T, Shirakawa K, Masuyama H, et al. Minimal change oesophagitis: a disease with characteristic differences to erosive esophagitis. Aliment Pharmacol Ther. 2005;21 Suppl 2:19–26.PubMedCrossRef

Spechler SJ. Clinical practice. Barrett’s esophagus. N Engl J Med. 2002;346:836–42.PubMedCrossRef

10.

Falk GW, Rice TW, Goldblum JR, et al. Jumbo biopsy forceps protocol still misses unsuspected cancer in Barrett’s esophagus with high grade dysplasia. Gastrointest Endosc. 1999;49:170–6.PubMedCrossRef

11.

Kim SL, Waring JP, Spechler SJ, et al. Diagnostic inconsistencies in Barrett’s esophagus. Department of Veterans Affairs Gastroesophageal Reflux Study Group. Gastroenterology. 1994;107:945–9.PubMed

12.

Bergman JJGHM, Tytgat GNJ. New developments in the endoscopic surveillance of Barrett’s oesophagus. Gut. 2005;54 Suppl I:i38–42.PubMedCrossRef

13.

Reddymasu SC, Sharma P. Advances in endoscopic imaging of the esophagus. Gastroenterol Clin North Am. 2008;37:763–74.PubMedCrossRef

14.

Kiesslich R, Kanzler S, Vieth M, et al. Minimal change esophagitis: prospective comparison of endoscopic and histological markers between patients with non-erosive reflux disease and normal controls using magnifying endoscopy. Dig Dis. 2004;22:221–7.PubMedCrossRef

15.

Edebo A, Tam W, Bruno M, et al. Magnification endoscopy for diagnosis of nonerosive reflux disease: a proposal of diagnostic criteria and critical analysis of observer variability. Endoscopy. 2007;39:195–201.PubMedCrossRef

16.

Guelrud M, Herrera I, Essenfeld H, et al. Enhanced magnification endoscopy: a new technique to identify specialized intestinal metaplasia in Barrett’s esophagus. Gastrointest Endosc. 2001;53:559–65.PubMedCrossRef

17.

Endo T, Awakawa T, Takahashi H, et al. Classification of Barrett’s epithelium by magnifying endoscopy. Gastrointest Endosc. 2002;55:641–7.PubMedCrossRef

18.

Sharma P, Weston AP, Topalovski M, et al. Magnification chromoendoscopy for the detection of intestinal metaplasia and dysplasia in Barrett’s oesophagus. Gut. 2003;52:24–7.PubMedCrossRef

19.

Yoshikawa I, Yamasaki M, Yamasaki T, et al. Lugol chromoendoscopy as a diagnostic tool in so-called endoscopy-negative GERD. Gastrointest Endosc. 2005;62:698–703.PubMedCrossRef

20.

Canto MI, Setrakian S, Willis J, et al. Methylene blue-directed biopsies improve detection of intestinal metaplasia and dysplasia in Barrett’s esophagus. Gastrointest Endosc. 2000;51:560–8.PubMedCrossRef

21.

Horwhat JD, Maydonovitch CL, Ramos F, et al. A randomized comparison of methylene blue-directed biopsy versus conventional four-quadrant biopsy for the detection of intestinal metaplasia and dysplasia in patients with long-segment Barrett’s esophagus. Am J Gastroenterol. 2008;103:546–54.PubMedCrossRef

22.

Olliver JR, Wild CP, Sahay P, et al. Chromoendoscopy with methylene blue and associated DNA damage in Barrett’s oesophagus. Lancet. 2003;362:373–4.PubMedCrossRef

23.

Curvers W, Baak L, Kiesslich R, et al. Chromoendoscopy and narrow-band imaging compared with high-resolution magnification endoscopy in Barrett’s esophagus. Gastroenterology. 2008;134:670–9.PubMedCrossRef

24.

Kara MA, Peters FP, Rosmolen WD, et al. High-resolution endoscopy plus chromoendoscopy or narrow-band imaging in Barrett’s esophagus: a prospective randomized crossover study. Endoscopy. 2005;37:929–36.PubMedCrossRef

25.

Banerjee R, Reddy DN. Advanced Gastrointestinal Endoscopy: A Primer on Narrow Band Imaging. Hyderabad: Paras Medical Publisher; 2009; p. 5–26.

26.

Dent J, Armstrong D, Delaney B, et al. Symptom evaluation in reflux disease: workshop background, processes, terminology, recommendations and discussion outputs. Gut. 2004;53 Suppl 4:1–24.

27.

Sharma P, Wani S, Bansal A, et al. A feasibility trial of narrow band imaging endoscopy in patients with gastroesophageal reflux disease. Gastroenterology. 2007;133:454–64.PubMedCrossRef

28.

Banerjee R, Pratap N, Ramchandani M, Tandan M, Rao GV, Reddy DN. Narrow band imaging (NBI) can detect minimal changes in non erosive reflux disease (NERD), which resolve with PPI therapy. Gastrointest Endosc. 2009;69:AB356.CrossRef

29.

Tseng PH, Chen CC, Chiu HM, et al. Performance of narrow band imaging and magnification endoscopy in the prediction of therapeutic response in patients with gastroesophageal reflux disease. J Clin Gastroenterol. 2011;45:501–6.PubMedCrossRef

30.

Lee YC, Lin JT, Chiu HM, et al. Intraobserver and interobserver consistency for grading esophagitis with narrow-band imaging. Gastrointest Endosc. 2007;66:230–6.PubMedCrossRef

31.

Banerjee R, Reddy DN. Minimal-change esophagitis on narrow band imaging. Clin Gastroenterol Hepatol. 2008;6:A26–A26.e1. Epub 2008 Jun 4.PubMedCrossRef

32.

Fock KM, Teo EK, Ang TL, et al. The utility of narrow band imaging in improving the endoscopic diagnosis of gastroesophageal disease. Clin Gastroenterol Hepatol. 2009;7:54–9.

33.

Kara MA, Ennahachi M, Fockens P, et al. Detection and classification of the mucosal and vascular patterns (mucosal morphology) in Barrett’s esophagus by using narrow band imaging. Gastrointest Endosc. 2006;64:155–66.PubMedCrossRef

34.

Sharma P, Bansal A, Mathur S, et al. The utility of a novel narrow band imaging endoscopy system in patients with Barrett’s esophagus. Gastrointest Endosc. 2006;64:167–75.PubMedCrossRef

35.

Goda K, Tajiri H, Ikegami M, et al. Usefulness of magnifying endoscopy with narrow band imaging for the detection of specialized intestinal metaplasia in columnar-lined esophagus and Barrett’s adenocarcinoma. Gastrointest Endosc. 2007;65:36–46.PubMedCrossRef

36.

Singh R, Anagnostopoulos GK, Yao K, et al. Narrow-band imaging with magnification in Barrett’s esophagus: validation of a simplified grading system of mucosal morphology patterns against histology. Endoscopy. 2008;40:457–63.PubMedCrossRef

37.

Mannath J, Subramanian V, Hawkey CJ, et al. Narrow band imaging for characterization of HGD and SIM in Barrett’s esophagus: a meta-analysis. Endoscopy. 2010;42:351–9.PubMedCrossRef

38.

Hamamoto Y, Endo T, Nosho K, et al. Usefulness of narrow-band imaging endoscopy for diagnosis of Barrett’s esophagus. J Gastroenterol. 2004;39:14–20.PubMedCrossRef

39.

Curvers WL, Bohmer CJ, Mallant-Hent RC, et al. Mucosal morphology in Barrett’s esophagus: interobserver agreement and role of narrow band imaging. Endoscopy. 2008;40:799–805.PubMedCrossRef

40.

Singh R, Karageorgiou H, Owen V, et al. Comparison of high-resolution magnification narrow-band imaging and white-light endoscopy in the prediction of histology in Barrett’s oesophagus. Scand J Gastroenterol. 2009;44:85–92.PubMedCrossRef

41.

Wolfsen HC, Crook JE, Krishna M, et al. Prospective, controlled tandem endoscopy study of narrow band imaging for dysplasia detection in Barrett’s esophagus. Gastroenterology. 2008;135:24–31.PubMedCrossRef

42.

Curvers WL, van Vilsteren FG, Baak LC, et al. Endoscopic trimodal imaging versus standard video endoscopy for detection of early Barrett’s neoplasia: a multicenter, randomized, crossover study in general practice. Gastrointest Endosc. 2011;73:195–203.PubMedCrossRef

43.

Hoffman A, Basting N, Goetz M, et al. High definition endoscopy with i-Scan and Lugol’s solution for more precise detection of mucosal breaks in patients with reflux symptoms. Endoscopy. 2009;41:107–12.PubMedCrossRef

44.

Chaiteerakij R, Geratikornsupuk N, Tangmankongworakoon N, et al. Efficacy of intelligent chromo endoscopy for detection of minimal mucosal breaks in patients with typical reflux symptoms of gastroesophageal reflux disease. Gastrointest Endosc. 2008;67:AB86.CrossRef

45.

Falk GW. Autofluorescence endoscopy. Gastrointest Endosc Clin North Am. 2009;19:209–20.CrossRef

46.

Kara MA, Peters FP, Ten Kate FJ, et al. Endoscopic video autofluorescence imaging may improve the detection of early neoplasia in patients with Barrett’s esophagus. Gastrointest Endosc. 2005;61:679–85.PubMedCrossRef

47.

Kumagai Y, Inoue H, Nagai K, et al. Magnifying endoscopy, stereoscopic microscopy, and the microvascular architecture of superficial esophageal carcinoma. Endoscopy. 2002;34:369–75.

48.

Yoshida T, Inoue H, Usui S, Satodate H, Fukami N, Kudo SE. Narrow-band imaging system with magnifying endoscopy for superficial esophageal lesions. Gastrointest Endosc. 2004;59:288–95.

49.

Kara MA, Peters FP, Fockens P, et al. Endoscopic video-autofluorescence imaging followed by narrow band imaging for detecting early neoplasia in Barrett’s esophagus. Gastrointest Endosc. 2006;64:176–85.PubMedCrossRef

50.

Curvers WL, Singh R, Song LM, et al. Endoscopic tri-modal imaging for detection of early neoplasia in Barrett’s oesophagus: a multi-centre feasibility study using high-resolution endoscopy, autofluorescence imaging and narrow band imaging incorporated in one endoscopy system. Gut. 2008;57:167–72.PubMedCrossRef

51.

Curvers WL, Herrero LA, Wallace MB, et al. Endoscopic tri-modal imaging is more effective than standard endoscopy in identifying early-stage neoplasia in Barrett’s esophagus. Gastroenterology. 2010;139:1106–14.PubMedCrossRef

52.

Nguyen NQ, Leong RW. Current application of confocal endomicroscopy in gastrointestinal disorders. J Gastroenterol Hepatol. 2008;23:1483–91.PubMedCrossRef

53.

Becker V, Vieth M, Bajbouj M, et al. Confocal laser scanning fluorescence microscopy for in vivo determination of microvessel density in Barrett’s esophagus. Endoscopy. 2008;40:888–91.PubMedCrossRef

54.

Kiesslich R, Gossner L, Goetz M, et al. In vivo histology of Barrett’s esophagus and associated neoplasia by confocal laser endomicroscopy. Clin Gastroenterol Hepatol. 2006;4:979–87.PubMedCrossRef

55.

Bajbouj M, Vieth M, Rösch T, et al. Probe-based confocal laser endomicroscopy compared with standard four-quadrant biopsy for evaluation of neoplasia in Barrett’s esophagus. Endoscopy. 2010;42:435–40.PubMedCrossRef

56.

Canto MI. Endomicroscopy of Barrett’s esophagus. Gastroenterol Clin North Am. 2010;39:759–69.PubMedCrossRef

57.

Evans JA, Bouma BE, Bressner J, et al. Identifying intestinal metaplasia at the squamocolumnar junction by using optical coherence tomography. Gastrointest Endosc. 2007;65:50–6.PubMedCrossRef

58.

Cobb MJ, Hwang JH, Upton MP, et al. Imaging of subsquamous Barrett’s epithelium with ultrahigh-resolution optical coherence tomography: a histologic correlation study. Gastrointest Endosc. 2010;71:223–30.PubMedCrossRef

59.

Wallace MB, Wax A, Roberts DN, et al. Reflectance spectroscopy. Gastrointest Endosc Clin North Am. 2009;19:233–42.CrossRef

60.

Li M, Anastassiades CP, Joshi B, et al. Affinity peptide for targeted detection of dysplasia in Barrett’s esophagus. Gastroenterology. 2010;139:1472–80.PubMedCrossRef

Title: Enhanced endoscopic imaging and gastroesophageal reflux disease
Authors: Rupa Banerjee
D. Nageshwar Reddy
Publication date: 01-09-2011
Publisher: Springer-Verlag
Published in: Indian Journal of Gastroenterology / Issue 5/2011
Print ISSN: 0254-8860
Electronic ISSN: 0975-0711
DOI: https://doi.org/10.1007/s12664-011-0137-1

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