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Published in: BMC Pediatrics 1/2020

Open Access 01-12-2020 | Endoscopy | Technical advance

An innovative method for manufacturing the Tuebingen palatal plate for infants with Robin sequence

Authors: Silvia Müller-Hagedorn, Jörg Arand, Thilo Scholz, Christian F. Poets, Cornelia Wiechers

Published in: BMC Pediatrics | Issue 1/2020

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Abstract

Background

Robin sequence (RS) is characterized by mandibular micro- and retrognathia, glossoptosis, upper airway obstruction and optionally a cleft palate. With an incidence of 1:8000, it belongs to the so-called rare diseases; 30–50% of patients have RS as part of a syndrome. A comparatively well-studied treatment option is the Tuebingen Palatal Plate (TPP), which has proven effective in both, isolated and syndromic RS, but often requires multiple endoscopies for perfect fit and effectiveness. We report on a new method for fitting the TPP with only one session of nasopharyngeal endoscopy resulting in the plate being finished in one day.

Methods and results

First, a prototype is produced, consisting of a traditional acrylic palatal part and a velar extension made of thermoplastic resin, usually measuring 10x40mm. Using polymerization, a scale is added to the posterior part of the extension to help with determining its optimal length during endoscopic evaluation. The extension is pre-bent in the dental laboratory to achieve an approximate shape. During endoscopy, the prototype can be adjusted to the infant’s anatomy: first, the angulation is customized by controlled heating, bending and cooling of the thermoplastic spur. Second, the length of the spur is adapted by grinding its tip. Then the prototype is returned to the dental laboratory for completion; the final plate can be delivered to the patient on the same day. It acts by shifting the tongue into a more anterior position, thereby opening the airway and releasing upper airway obstruction, as well as by acting as a functional orthodontic appliance that stimulates mandibular growth through exerting pressure on the base of the tongue.

Conclusions

With the thermoplastic spur presented here, a TPP can be produced within one day, requiring only one endoscopy. This approach may facilitate fabricating the TPP.
Literature
1.
go back to reference Vatlach S, Maas C, Poets CF. Birth prevalence and initial treatment of Robin sequence in Germany: a prospective epidemiologic study. Orphanet J Rare Dis. 2014;9:9–13.CrossRef Vatlach S, Maas C, Poets CF. Birth prevalence and initial treatment of Robin sequence in Germany: a prospective epidemiologic study. Orphanet J Rare Dis. 2014;9:9–13.CrossRef
2.
go back to reference Izumi K, Konczal LL, Mitchell AL, Jones MC. Underlying genetic diagnosis of Pierre Robin sequence: retrospective chart review at two Children’s hospitals and a systematic literature review. J Pediatr. 2012;160:645–50.CrossRef Izumi K, Konczal LL, Mitchell AL, Jones MC. Underlying genetic diagnosis of Pierre Robin sequence: retrospective chart review at two Children’s hospitals and a systematic literature review. J Pediatr. 2012;160:645–50.CrossRef
3.
go back to reference Cohen MM Jr. Robin sequences and complexes: causal heterogeneity and pathogenic/phenotypic variability. Am J Med Genet. 1999;84:311–5.CrossRef Cohen MM Jr. Robin sequences and complexes: causal heterogeneity and pathogenic/phenotypic variability. Am J Med Genet. 1999;84:311–5.CrossRef
4.
go back to reference Sher AE, Shprintzen RJ, Thorpy MJ. Endoscopic observations of obstructive sleep apnea in children with anomalous upper airways: predictive and therapeutic value. Int J Pediatr Otorhinolaryngol. 1986;11:135–46.CrossRef Sher AE, Shprintzen RJ, Thorpy MJ. Endoscopic observations of obstructive sleep apnea in children with anomalous upper airways: predictive and therapeutic value. Int J Pediatr Otorhinolaryngol. 1986;11:135–46.CrossRef
5.
go back to reference Marques IL, de Sousa TV, Carneiro AF, Barbieri MA, Bettiol H, Perreira Gutierrez MR. Clinical experience with infants with Robin sequence: a prospective study. Cleft Palate Craniofac J. 2001;38:171–8.CrossRef Marques IL, de Sousa TV, Carneiro AF, Barbieri MA, Bettiol H, Perreira Gutierrez MR. Clinical experience with infants with Robin sequence: a prospective study. Cleft Palate Craniofac J. 2001;38:171–8.CrossRef
6.
go back to reference Poets CF, Bacher M. Treatment of upper airway obstruction and feeding problems in Robin-like phenotype. J Pediatr. 2011;151:887–92.CrossRef Poets CF, Bacher M. Treatment of upper airway obstruction and feeding problems in Robin-like phenotype. J Pediatr. 2011;151:887–92.CrossRef
7.
go back to reference Maas C, Poets CF. Initial treatment and early weight gain of children with Robin sequence in Germany: a prospective epidemiological study. Arch Dis Child Neonatol Ed. 2017;102(2):F142–6.CrossRef Maas C, Poets CF. Initial treatment and early weight gain of children with Robin sequence in Germany: a prospective epidemiological study. Arch Dis Child Neonatol Ed. 2017;102(2):F142–6.CrossRef
8.
go back to reference Buchenau W, Urschitz MS, Sautermeister J, Bacher M, Herberts T, Arand J, Poets CF. A randomized clinical trial of a new orthodontic appliance to improve upper airway obstruction in infants with Pierre Robin sequence. J Pediatr. 2007;151:145–9.CrossRef Buchenau W, Urschitz MS, Sautermeister J, Bacher M, Herberts T, Arand J, Poets CF. A randomized clinical trial of a new orthodontic appliance to improve upper airway obstruction in infants with Pierre Robin sequence. J Pediatr. 2007;151:145–9.CrossRef
9.
go back to reference Bacher M, Sautermeister J, Urschitz MS, Buchenau W, Arand J, Poets CF. An Oral appliance with velar extension for treatment of obstructive sleep apnea in infants with Pierre Robin sequence. Cleft Palate Craniofac J. 2011;48:331–6.CrossRef Bacher M, Sautermeister J, Urschitz MS, Buchenau W, Arand J, Poets CF. An Oral appliance with velar extension for treatment of obstructive sleep apnea in infants with Pierre Robin sequence. Cleft Palate Craniofac J. 2011;48:331–6.CrossRef
10.
go back to reference Buchenau W, Wenzel S, Bacher M, Müller-Hagedorn S, Arand J, Poets CF. Functional treatment of airway obstruction and feeding problems in infants with Robin sequence. Arch Dis Child Fetal Neonatol Ed. 2017;102:F142–6.CrossRef Buchenau W, Wenzel S, Bacher M, Müller-Hagedorn S, Arand J, Poets CF. Functional treatment of airway obstruction and feeding problems in infants with Robin sequence. Arch Dis Child Fetal Neonatol Ed. 2017;102:F142–6.CrossRef
11.
go back to reference Poets, CF, Maas C, Buchenau W, Arand J, Vierzig A, Braumann B, Müller-Hagedorn S. Multicenter study on the effectiveness of the pre-epiglottic baton plate for airway obstruction and feeding problems in Robin sequence Orphanet J of Rare Dis 2017; doi: https://doi.org/10.1186/s13023-017-0602-8 . Poets, CF, Maas C, Buchenau W, Arand J, Vierzig A, Braumann B, Müller-Hagedorn S. Multicenter study on the effectiveness of the pre-epiglottic baton plate for airway obstruction and feeding problems in Robin sequence Orphanet J of Rare Dis 2017; doi: https://​doi.​org/​10.​1186/​s13023-017-0602-8 .
13.
go back to reference Limbrock GJ, Castillo-Morales R, Hoyer H, Stöver B, Onufer CN. The Castillo Morales approach to orofacial to orofacial pathology in Down syndrome. Int J Orofacial Myology. 1993;19:30–7.PubMed Limbrock GJ, Castillo-Morales R, Hoyer H, Stöver B, Onufer CN. The Castillo Morales approach to orofacial to orofacial pathology in Down syndrome. Int J Orofacial Myology. 1993;19:30–7.PubMed
14.
go back to reference Brondo JJ. NMK-Neuromotorische Konzepte nach Brondo. In: Frey S, editor. Pädiatrisches Dysphagiemanagement-eine interdisziplinäre Herausforderung. München: Elsevier/Urban und Fischer; 2011. p. 315–6. Brondo JJ. NMK-Neuromotorische Konzepte nach Brondo. In: Frey S, editor. Pädiatrisches Dysphagiemanagement-eine interdisziplinäre Herausforderung. München: Elsevier/Urban und Fischer; 2011. p. 315–6.
16.
go back to reference McNamara JA Jr, Carlson DS. Quantitative analysis of temporomandibular joint adaptations to protrusive function. Am J Orthod. 1979;76:593–611.CrossRef McNamara JA Jr, Carlson DS. Quantitative analysis of temporomandibular joint adaptations to protrusive function. Am J Orthod. 1979;76:593–611.CrossRef
Metadata
Title
An innovative method for manufacturing the Tuebingen palatal plate for infants with Robin sequence
Authors
Silvia Müller-Hagedorn
Jörg Arand
Thilo Scholz
Christian F. Poets
Cornelia Wiechers
Publication date
01-12-2020
Publisher
BioMed Central
Keyword
Endoscopy
Published in
BMC Pediatrics / Issue 1/2020
Electronic ISSN: 1471-2431
DOI
https://doi.org/10.1186/s12887-020-2009-2

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