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01-03-2020 | Review Article

Endoscopic submucosal dissection versus transanal endoscopic surgery for the treatment of early rectal tumor: a systematic review and meta-analysis

Authors: Vitor Massaro Takamatsu Sagae, Igor Braga Ribeiro, Diogo Turiani Hourneaux de Moura, Vitor Ottoboni Brunaldi, Fernanda Prado Logiudice, Mateus Pereira Funari, Elisa Ryoka Baba, Wanderley Marques Bernardo, Eduardo Guimarães Hourneaux de Moura

Published in: Surgical Endoscopy | Issue 3/2020

Abstract

Background

Minimally invasive treatment of early-stage rectal lesion has presented good results, with lower morbidity than surgical resection. Transanal endoscopic microsurgery (TEM) and transanal minimally invasive surgery (TAMIS) are the main methods of transanal surgery. However, endoscopic submucosal dissection (ESD) has been gaining ground because it allows en bloc resections with low recurrence rates. The aim of this study was to analyze ESD in comparison with transanal endoscopic surgery.

Methods

We searched MEDLINE, EMBASE, SciELO, Cochrane CENTRAL, and Lilacs/Bireme with no restrictions on the date or language of publication. The outcomes evaluated were recurrence rate, complete (R0) resection rate, en bloc resection rate, length of hospital stay, duration of the procedure, and complication rate.

Results

Six retrospective cohort studies involving a collective total of 326 patients—191 in the ESD group and 135 in the transanal endoscopic surgery group were conducted. There were no statistically significant differences between the groups for any of the outcomes evaluated.

Conclusions

For the minimally invasive treatment of early rectal tumor, ESD and surgical techniques do not differ in terms of local recurrence, en bloc resection rate, R0 resection rate, duration of the procedure, length of hospital stay, or complication rate, however, evidence is very low.

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Title: Endoscopic submucosal dissection versus transanal endoscopic surgery for the treatment of early rectal tumor: a systematic review and meta-analysis
Authors: Vitor Massaro Takamatsu Sagae
Igor Braga Ribeiro
Diogo Turiani Hourneaux de Moura
Vitor Ottoboni Brunaldi
Fernanda Prado Logiudice
Mateus Pereira Funari
Elisa Ryoka Baba
Wanderley Marques Bernardo
Eduardo Guimarães Hourneaux de Moura
Publication date: 01-03-2020
Publisher: Springer US
Published in: Surgical Endoscopy / Issue 3/2020
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-019-07271-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Endoscopic submucosal dissection versus transanal endoscopic surgery for the treatment of early rectal tumor: a systematic review and meta-analysis

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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