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Surgical Endoscopy

Published in:

01-01-2009

Endoscopic resection of ampullary tumors: 12-year review of 21 cases

Authors: Jaume Boix, Vicente Lorenzo-Zúñiga, Vicente Moreno de Vega, Eugeni Domènech, Miquel Angel Gassull

Published in: Surgical Endoscopy | Issue 1/2009

Abstract

Background

Endoscopic snare papillectomy is increasingly performed with curative intent for benign papillary tumors. This study aimed to evaluate the outcome of endoscopic resection for ampullary tumors at a single center.

Methods

All ampullary tumors without macroscopic features of malignancy identified by the endoscopic retrograde cholangiopancreatography (ERCP) from January 1995 to February 2007 were included in the study. Papillectomy was performed by snare resection using electrocautery. Argon plasma coagulation was effective for fulguration of small tissue remnants not amenable to snare resection.

Results

Of the 21 patients (9 men and 12 women; mean age, 67.2 ± 14.3 years) evaluated, 11 had adenoma (7 had low-grade dysplasia [LGD] and 4 had high-grade dysplasia [HGD]), and 10 had carcinoma. All the patients underwent papillectomy. Of the 21 patients, 18 had extraductal growth or minimal intraductal growth, and 3 had extensive intraductal growth. The endoscopic complications (23.8%) included one case of mild bleeding, two cases of mild pancreatitis, and two cases of moderate pancreatitis. After papillectomy, 15 patients underwent Whipple procedures (endoscopic failure, 74.1%), including 3 patients with extensive intraductal growth (complete removal of the lesion impossible), 9 patients with carcinoma beyond the mucosal layer, and 3 patients with recurrence treated surgically. Endoscopic success (28.5%) was obtained for the remaining six patients (4 with LGD and 2 with HGD). Papillectomy was determined to be curative after a mean follow-up period of 15.9 ± 14.9 months.

Conclusions

In the hands of an experienced endoscopist, endoscopic papillectomy is a clinically effective treatment for ampullary tumors without invasive neoplasia. Evaluation of a prepapillectomy tumor extension is an important criterion for assessment of endoscopic success.

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Title: Endoscopic resection of ampullary tumors: 12-year review of 21 cases
Authors: Jaume Boix
Vicente Lorenzo-Zúñiga
Vicente Moreno de Vega
Eugeni Domènech
Miquel Angel Gassull
Publication date: 01-01-2009
Publisher: Springer-Verlag
Published in: Surgical Endoscopy / Issue 1/2009
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-008-9866-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Endoscopic resection of ampullary tumors: 12-year review of 21 cases

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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