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Surgical Endoscopy

Published in:

01-04-2017

Endoscopic resection for duodenal subepithelial tumors: a single-center experience

Authors: Tae Wook Kim, Gwang Ha Kim, Do Youn Park, Sangjeong Ahn, Won Lim, Bon Eun Lee, Geun Am Song

Published in: Surgical Endoscopy | Issue 4/2017

Abstract

Background

Subepithelial tumors (SETs) in the gastrointestinal tract are often incidentally found during endoscopic examinations. Although the utility and safety of endoscopic resection (ER) of SETs in the esophagus and stomach have been described, data about the ER of duodenal SETs remain scant. Therefore, we aimed to investigate the clinical outcomes associated with the ER of duodenal SETs and to assess possible predictive factors for incomplete resection.

Methods

We conducted a retrospective observational study of 62 patients (64 lesions) that underwent ER of duodenal SETs between June 2005 and December 2015 at the Pusan National University Hospital. The therapeutic outcomes from ER and procedure-related complications were analyzed.

Results

Endoscopic mucosal resection (EMR) was performed in 38 tumors, EMR with a ligation device (EMR-L) in 18 and endoscopic submucosal dissection (ESD) in 8. The overall en bloc resection and complete ER rates were 96.9 % (62/64) and 100 % (64/64), respectively. The complete pathologic resection rate was 76.6 % (49/64). Multivariate logistic regression analyses determined that the macroscopic type (Yamada type I or II; odds ratio [OR] 6.460, 95 % confidence interval [CI] 1.569–37.458, p = 0.027) and the treatment method (ESD; OR 7.178, 95 % CI 1.291–39.323, p = 0.024) were independently associated with incomplete pathologic resection. The procedure-related bleeding and perforation rates were 6.3 % and 4.7 %, respectively. No recurrences were observed in patients who had undergone complete ER at a median follow-up period of 20 months (range 6–112 months).

Conclusion

ER is an effective, safe, and feasible treatment for duodenal SETs, especially when the SET is located in the deep mucosal layer and/or the submucosal layer.

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Title: Endoscopic resection for duodenal subepithelial tumors: a single-center experience
Authors: Tae Wook Kim
Gwang Ha Kim
Do Youn Park
Sangjeong Ahn
Won Lim
Bon Eun Lee
Geun Am Song
Publication date: 01-04-2017
Publisher: Springer US
Published in: Surgical Endoscopy / Issue 4/2017
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-016-5200-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Endoscopic resection for duodenal subepithelial tumors: a single-center experience

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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