Published in:
Open Access
01-12-2022 | Letter
Empirical comparisons of heterogeneity magnitudes of the risk difference, relative risk, and odds ratio
Authors:
Yuxi Zhao, Elizabeth H. Slate, Chang Xu, Haitao Chu, Lifeng Lin
Published in:
Systematic Reviews
|
Issue 1/2022
Login to get access
Excerpt
In epidemiology and medical research, the choices of effect measures for binary outcomes have been long debated. Common choices include the risk difference (RD), relative risk (RR), and odds ratio (OR). The RD is often considered more heterogeneous than the ratio measures, RR and OR [
1,
2]. Nevertheless, the arguments supporting this claim have been challenged [
3]. For example, more rejections of homogeneity in hypothesis testing of RDs are expected than those of ORs. This article empirically compares the heterogeneity magnitudes between the RD, RR, and OR. …