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European Archives of Oto-Rhino-Laryngology

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01-03-2013 | Otology

Electrophysiological mapping of the cochlear nucleus with multi-channel bipolar surface microelectrodes

Authors: Kiyoshi Oda, Tetsuaki Kawase, Daisuke Yamauchi, Hiroshi Hidaka, Toshimitsu Kobayashi

Published in: European Archives of Oto-Rhino-Laryngology | Issue 3/2013

Abstract

Auditory potentials in response to electrical stimulation of the cochlear nucleus were recorded in guinea pigs using two types of multi-channel surface microelectrodes with inter-electrode distance of 100 and 200 μm. Unequivocal waves of electrically evoked auditory brainstem responses (EABRs), which increased in amplitude with increasing stimulation current, were consistently observed. Electrophysiological mapping with these multichannel electrodes could clearly distinguish stimulation points showing positive EABRs from points showing undetectable EABRs, indicating that multi-channel surface microelectrodes have great potential in clinical use to determine the optimal location for the positioning of auditory brainstem implants, and may allow more precise discrimination of pitch. Further study to clarify the optimal inter-electrode distance for humans is necessary before application to physiological mapping in the human cochlear nucleus.

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Title: Electrophysiological mapping of the cochlear nucleus with multi-channel bipolar surface microelectrodes
Authors: Kiyoshi Oda
Tetsuaki Kawase
Daisuke Yamauchi
Hiroshi Hidaka
Toshimitsu Kobayashi
Publication date: 01-03-2013
Publisher: Springer-Verlag
Published in: European Archives of Oto-Rhino-Laryngology / Issue 3/2013
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-012-2077-5

At a glance: The STEP trials

Springer Medicine

Electrophysiological mapping of the cochlear nucleus with multi-channel bipolar surface microelectrodes

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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