Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Annals of Nuclear Medicine
Published in: Annals of Nuclear Medicine 5/2015

01-06-2015 | Original Article

Elastofibroma dorsi incidentally detected by 18F-FDG PET/CT imaging

Authors: Seval Erhamamci, Mehmet Reyhan, Gul Nihal Nursal, Nese Torun, Ali Fuat Yapar, Alper Findikcioglu, Tuba Canpolat

Published in: Annals of Nuclear Medicine | Issue 5/2015

Login to get access

Abstract

Objective

Elastofibroma dorsi (ED) is a rare pseudotumor of the soft tissues that can also show 18F-fluorodeoxyglucose (18F-FDG) uptake on positron emission tomography combined with computed tomography (PET/CT) imaging. The aim of this retrospectively study was to describe the metabolic characteristics of ED incidentally detected by 18F-FDG PET/CT imaging.

Materials and Methods

Between November 2009 and August 2013 at our institution, 10,350 consecutive PET/CT examinations were retrospectively investigated. In 176 of these patients, ED was recorded as an incidental finding. Fifty-five of 176 patients also had follow-up scans after chemoradiotherapy. A total of 231 scans with ED in 176 patients were identified. To determine the metabolic activity of ED, the maximum standardized uptake value (SUVmax) was calculated semiquantitatively. For measurement size of ED, the longest axis of transaxial CT images was used. Seven of the 176 patients underwent surgery due to suspected metastases and/or invasion of primary malignancy and/or symptoms or incidental during surgery.

Results

The prevalence of ED in our series was 1.7 %. The lesions were located in the subscapular region in all patients, except in one case with a lesion in the infrascapular region. A total of 419 ED lesions in 231 scan of 176 patients were evaluated. Mean ± SD SUVmax and long axis values for these 419 lesions were 2.31 ± 0.61 (range 1.0–4.30) and 56.78 ± 17.01 mm (range 19–112 mm), respectively. Of these 176 patients, 141 (80.1 %) had bilateral lesions and 35 (19.9 %) had unilateral lesions. There were statistically significant differences in the SUVmax and long axis values between the right and left side in the bilateral lesions (p = 0.001). No significant differences in the SUVmax and long axis values of the lesion were found between pre- and posttreatment in the patients with follow-up scans.

Conclusion

Elastofibroma dorsi located in the scapular region is usually bilateral, asymmetric and with mild or moderate metabolic activity on PET/CT imaging. In addition, the metabolic activity and size of ED remained stable after chemoradiotherapy. Awareness of these metabolic characteristics of ED is important for preventing misinterpretation during 18F-FDG PET/CT studies.
Literature
1.
Metser U, Miller E, Lerman H, Even-Sapir E. Benign nonphysiologic lesions with increased 18F-FDG uptake on PET/CT: characterization and incidence. AJR Am J Roentgenol. 2007;189:1203–10.PubMedCrossRef
2.
Metser U, Even-Sapir E. Increased (18)F-fluorodeoxyglucose uptake in benign, nonphysiologic lesions found on whole-body positron emission tomography/computed tomography (PET/CT): accumulated data from four years of experience with PET/CT. Semin Nucl Med. 2007;37:206–22.PubMedCrossRef
3.
Patrikeos A, Breidahl W, Robins P. F-18 FDG uptake associated with elastofibroma dorsi. Clin Nucl Med. 2005;30:617–8.PubMedCrossRef
4.
Wasyliw CW, Caride VJ. Incidental detection of bilateral elastofibroma dorsi with F-18 FDG PET/CT. Clin Nucl Med. 2005;30:700–1.PubMedCrossRef
5.
Pierce JC III, Henderson R. Hypermetabolism of elastofibroma dorsi on PET-CT. AJR. 2004;183:35–7.PubMedCrossRef
6.
Kinge AR, Arabi M, Al-Kutoubi A, Otrock ZK, Shamseddine A. Elastofibroma dorsi mimicking metastatic disease on fluorodeoxyglucose F-18 positron emission tomography in a breast cancer patient. Clin Oncol (R Coll Radiol). 2007;19:633–4.CrossRef
7.
Rotger A, Trifirò G, Travaini LL, de Cicco C, Paganelli G. Carcinoma, tuberculosis and elastofibroma in one patient: is [18F]FDG-PET/CT helpful? Rev Esp Med Nucl. 2009;28:22–5.PubMedCrossRef
8.
Blumenkrantz Y, Bruno GL, González CJ, Namías M, Osorio AR, Parma P. Characterization of elastofibroma dorsi with (18)FDG PET/CT: a retrospective study. Rev Esp Med Nucl. 2011;30:342–5.PubMedCrossRef
9.
Onishi Y, Kitajima K, Senda M, Sakamoto S, Suzuki K, Maeda T, et al. FDG-PET/CT imaging of elastofibroma dorsi. Skelet Radiol. 2011;40:849–53.CrossRef
10.
Nagamine N, Nohara Y, Ito E. Elastofibroma in Okinawa. A clinicopathologic study of 170 cases. Cancer. 1982;50:1794–805.PubMedCrossRef
11.
Brandser EA, Goree JC, El-Khoury GY. Elastofibroma dorsi: prevalence in an elderly patient population as revealed by CT. AJR Am J Roentgenol. 1998;171:977–80.PubMedCrossRef
12.
Naylor MF, Nascimento AG, Sherrick AD, Mcleod RA. Elastofibroma dorsi: radiologic findings in 12 patients. AJR. 1996;167:683–7.PubMedCrossRef
13.
Battaglia M, Vanel D, Pollastri P, Balladelli A, Alberghini M, Staals EL, et al. Imaging patterns in elastofibroma dorsi. Eur J Radiol. 2009;72:16–21.PubMedCrossRef
14.
Findikcioglu A, Kilic D, Karadayi Ş, Canpolat T, Reyhan M, Hatipoglu A. A thoracic surgeon’s perspective on the elastofibroma dorsi: a benign tumor of the deep infrascapular region. Thorac Cancer. 2013;4:35–40.CrossRef
15.
Jarvi OH, Lansimies PH. Subclinical elastofibromas in the scapular region in an autopsy series. Acta Pathol Microbiol Scand A. 1975;83:87–108.PubMed
16.
Lococo F, Cesario A, de Franco S, Ricchetti T, Sgarbi G, Treglia G. Is 18FDG PET/CT evaluation really useful in the diagnosis of elastofibroma dorsi? Rev Esp Med Nucl Imagen Mol. 2014;33:62.PubMed
Metadata
Title
Elastofibroma dorsi incidentally detected by 18F-FDG PET/CT imaging
Authors
Seval Erhamamci
Mehmet Reyhan
Gul Nihal Nursal
Nese Torun
Ali Fuat Yapar
Alper Findikcioglu
Tuba Canpolat
Publication date
01-06-2015
Publisher
Springer Japan
Published in
Annals of Nuclear Medicine / Issue 5/2015
Print ISSN: 0914-7187
Electronic ISSN: 1864-6433
DOI
https://doi.org/10.1007/s12149-015-0959-5

Other articles of this Issue 5/2015

Annals of Nuclear Medicine 5/2015 Go to the issue

Technical Note

Usefulness of the Chang attenuation correction method with use of a CT-based μ map by FBP reconstruction in 201Tl SPECT-MPI

Original Article

Update on nodal staging in non-small cell lung cancer with integrated positron emission tomography/computed tomography: a meta-analysis

Original Article

Impact of FDG-PET findings on decisions regarding patient management strategies: a multicenter trial in patients with lung cancer and other types of cancer

Original Article

Assessment of the prognostic capacity of pretreatment, interim, and post-therapy 18F-FDG PET/CT in extranodal natural killer/T-cell lymphoma, nasal type

Original Article

An exploratory efficacy study of the amyloid imaging agent [18F]flutemetamol in Japanese Subjects

Original Article

Nuclear myocardial perfusion imaging using thallium-201 with a novel multifocal collimator SPECT/CT: IQ-SPECT versus conventional protocols in normal subjects