Published in:
Open Access
01-12-2014 | Meeting abstract
EHMTI-0376. Trigeminovascular sensitisation by chronic subdural haemorrhage: four clinical paediatric cases
Authors:
W Squier, J Mack
Published in:
The Journal of Headache and Pain
|
Special Issue 1/2014
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Excerpt
Sensitisation of the trigeminal nerve (TG) has been extensively studied as a potential mechanism of migraine. Meningeal nociceptors project onto second order neurones of the trigeminocervical complex (TCC) via glutamate neurotransmission. Sensitisation of trigeminal afferents causes massive release of glutamate and central sensitisation. The TCC connects with the VII, IX and Xth cranial nerve nuclei, and participates in the trigeminocardiac reflex which is particularly important in the young . …