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Published in: Inflammopharmacology 2/2014

01-04-2014 | Short Communication

Efficacy of some colloidal silver preparations and silver salts against Proteus bacteria, one possible cause of rheumatoid arthritis

Authors: D. M. B. T. Disaanayake, Joan Faoagali, Hans Laroo, Gerald Hancock, Michael Whitehouse

Published in: Inflammopharmacology | Issue 2/2014

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Abstract

There has been increased interest in the role of anti-Proteus antibodies in the aetiology of rheumatoid arthritis (RA) and whether chemotherapeutic agents active against Proteus species might reduce the risk and/or exacerbations of RA. We examined the in vitro antibacterial effects of ten different silver preparations which were either ionic silver [Ag(I)] solutions or nanoparticulate silver (NPS) (Ag0) suspensions against ATCC and two wild (clinical) strains of Proteus. The data establish the low minimum inhibitory concentration and minimum bactericidal concentration of all the silver formulations tested against these four Proteus strains. In a pilot study, a potent NPS preparation ex vivo showed long-lasting anti-Proteus activity in a normal human volunteer.
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Metadata
Title
Efficacy of some colloidal silver preparations and silver salts against Proteus bacteria, one possible cause of rheumatoid arthritis
Authors
D. M. B. T. Disaanayake
Joan Faoagali
Hans Laroo
Gerald Hancock
Michael Whitehouse
Publication date
01-04-2014
Publisher
Springer Basel
Published in
Inflammopharmacology / Issue 2/2014
Print ISSN: 0925-4692
Electronic ISSN: 1568-5608
DOI
https://doi.org/10.1007/s10787-013-0198-0

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