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Published in: Acta Neurologica Belgica 3/2018

01-09-2018 | Review

Efficacy of low glycemic index treatment in epileptic patients: a systematic review

Authors: Shahabeddin Rezaei, Sara Harsini, Mona Kavoosi, Reza Shervin Badv, Maryam Mahmoudi

Published in: Acta Neurologica Belgica | Issue 3/2018

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Abstract

Low glycemic index treatment (LGIT) is one of the new kinds of ketogenic diet (KD), designed to simplify the implementation of the KD. To date, several studies have attempted to determine the efficacy of LGIT in patients with epilepsy; however, their results are debatable. This study aims to retrieve all the LGIT studies to shed light on LGIT efficacy in epileptic patients. Electronic literature databases including MEDLINE/PubMed, Web of Science, Scopus, EMBASE were searched in July 2017. Interventional or observational studies exploring the efficacy of LGIT were included in the study. The National Heart, Lung, and Blood Institute quality assessment tool was used for the quality assessment of included studies. Two hundred and eighteen records were retrieved through a literature search. Following the screening process, eight studies were included. According to the ratings of the quality assessment tool, four studies were classified as good and four were categorized as fair. The result of the current study reveals that LGIT has a beneficial effect in patients with intractable epilepsy. However, more high-quality studies are required to determine the efficacy of LGIT in patients with intractable epilepsy.
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Metadata
Title
Efficacy of low glycemic index treatment in epileptic patients: a systematic review
Authors
Shahabeddin Rezaei
Sara Harsini
Mona Kavoosi
Reza Shervin Badv
Maryam Mahmoudi
Publication date
01-09-2018
Publisher
Springer International Publishing
Published in
Acta Neurologica Belgica / Issue 3/2018
Print ISSN: 0300-9009
Electronic ISSN: 2240-2993
DOI
https://doi.org/10.1007/s13760-018-0881-4

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