Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
International Orthopaedics
Published in: International Orthopaedics 5/2009

01-10-2009 | Original Paper

Efficacy of aspiration and autogenous bone marrow injection in the treatment of simple bone cysts

Authors: Mohammed M. Zamzam, Alshahid A. Abak, Khalid A. Bakarman, Fawzi F. Al-Jassir, Khalid I. Khoshhal, Marwan M. Zamzami

Published in: International Orthopaedics | Issue 5/2009

Login to get access

Abstract

Twenty eight patients with simple bone cyst that were treated by aspiration and percutaneous autogenous bone marrow injection were reviewed to evaluate the treatment outcome. There were 18 boys and ten girls. Their mean age was 10.9 ± 2.75 years. Single injection was performed for 16 patients; the rest had double or triple injections. There were no operative complications. The mean follow-up was 34.7 ± 6.87 months. The procedure succeeded in obtaining healing in 23 cysts (82%). Cysts with index of more than five and cortical thickness of less than 1 mm were significantly prone to pathological fractures and had significant poor results after treatment. Our results suggested that autogenous bone marrow injection is a safe and effective treatment method for simple bone cysts, but sometimes repeated injections are necessary. Cyst index and cortical thickness are good indicators for cyst aggressiveness and good predictors for treatment outcome.
Literature
1.
Arazi M, Senaran H, Memik R, Kapicioglu S (2005) Minimally invasive treatment of simple bone cysts with percutaneous autogenous bone marrow injection. Orthopedics 28(2):108–112PubMed
2.
Campanacci M, Capanna R, Picci P (1986) Unicameral and aneurysmal bone cysts. Clin Orthop Relat Res 204:25–36PubMed
3.
Chang CH, Stanton RP, Glutting J (2002) Unicameral bone cysts treated by injection of bone marrow or methylprednisolone. J Bone Joint Surg [Br] 84(3):407–412CrossRef
4.
Connolly JF (1998) Clinical use of marrow osteoprogenitor cells to stimulate osteogenesis. Clin Orthop Relat Res 355(Suppl):S257–S266PubMedCrossRef
5.
de Sanctis N, Andreacchio A (2006) Elastic stable intramedullary nailing is the best treatment of unicameral bone cysts of the long bones in children? Prospective long-term follow-up study. J Pediatr Orthop 26(4):520–525PubMed
6.
Delloye C, Docquier PL, Cornu O, Poilvache P, Peters M, Woitrin B, Rombouts JJ, De Nayer P (1998) Simple bone cysts treated with aspiration and a single bone marrow injection. A preliminary report. Int Orthop 22(2):134–138PubMedCrossRef
7.
Docquier PL, Delloye C (2003) Treatment of simple bone cysts with aspiration and a single bone marrow injection. J Pediatr Orthop 23(6):766–773PubMed
8.
Dormans JP, Sankar WN, Moroz L, Erol B (2005) Percutaneous intramedullary decompression, curettage, and grafting with medical-grade calcium sulfate pellets for unicameral bone cysts in children: a new minimally invasive technique. J Pediatr Orthop 25(6):804–811PubMedCrossRef
9.
Kaelin AJ, MacEwen GD (1989) Unicameral bone cysts. Natural history and the risk of fracture. Int Orthop 13(4):275–282PubMedCrossRef
10.
Kanellopoulos AD, Yiannakopoulos CK, Soucacos PN (2005) Percutaneous reaming of simple bone cysts in children followed by injection of demineralized bone matrix and autologous bone marrow. J Pediatr Orthop 25(5):671–675PubMedCrossRef
11.
Killian JT, Wilkinson L, White S, Brassard M (1998) Treatment of unicameral bone cyst with demineralized bone matrix. J Pediatr Orthop 18(5):621–624PubMedCrossRef
12.
Lokiec F, Ezra E, Khermosh O, Wientroub S (1996) Simple bone cysts treated by percutaneous autologous marrow grafting. A preliminary report. J Bone Joint Surg [Br] 78(6):934–937CrossRef
13.
Lokiec F, Wientroub S (1998) Simple bone cyst: etiology, classification, pathology, and treatment modalities. J Pediatr Orthop B 7(4):262–273PubMed
14.
Neer CS, Francis KC, Johnston AD, Kiernan HA Jr (1973) Current concepts on the treatment of solitary unicameral bone cyst. Clin Orthop Relat Res 97:40–51PubMedCrossRef
15.
Rougraff BT, Kling TJ (2002) Treatment of active unicameral bone cysts with percutaneous injection of demineralized bone matrix and autogenous bone marrow. J Bone Joint Surg [Am] 84(6):921–929
16.
Scaglietti O, Marchetti PG, Bartolozzi P (1979) The effects of methylprednisolone acetate in the treatment of bone cysts. Results of three years follow-up. J Bone Joint Surg [Br] 61(2):200–204
17.
Tsuchiya H, Abdel-Wanis ME, Uehara K, Tomita K, Takagi Y, Yasutake H (2002) Cannulation of simple bone cysts. J Bone Joint Surg [Br] 84(2):245–248CrossRef
18.
Yandow SM, Lundeen GA, Scott SM, Coffin C (1998) Autogenic bone marrow injections as a treatment for simple bone cyst. J Pediatr Orthop 18(5):616–620PubMedCrossRef
Metadata
Title
Efficacy of aspiration and autogenous bone marrow injection in the treatment of simple bone cysts
Authors
Mohammed M. Zamzam
Alshahid A. Abak
Khalid A. Bakarman
Fawzi F. Al-Jassir
Khalid I. Khoshhal
Marwan M. Zamzami
Publication date
01-10-2009
Publisher
Springer-Verlag
Published in
International Orthopaedics / Issue 5/2009
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-008-0619-7

Other articles of this Issue 5/2009

International Orthopaedics 5/2009 Go to the issue

Original Paper

Post-traumatic distal humerus non-union

Original Paper

Analysis of factors related to prognosis and curative effect for posterolateral fusion of lumbar low-grade isthmic spondylolisthesis

Original Paper

A cost analysis of treatment of tibial fracture nonunion by bone grafting or bone morphogenetic protein-7

Original Paper

Comparison of the efficacy of hook plate versus tension band wire in the treatment of unstable fractures of the distal clavicle

Original Paper

Clinical and biological assessment of cemented titanium femoral stems: an 11-year experience

Original Paper

Reimplantation of the resected tumour-bearing segment after recycling using liquid nitrogen for osteosarcoma