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Published in: Clinical Oral Investigations 4/2007

01-12-2007 | Original Article

Efficacy and tolerability of two home bleaching systems having different peroxide delivery

Authors: Christian Hannig, Dirk Lindner, Thomas Attin

Published in: Clinical Oral Investigations | Issue 4/2007

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Abstract

The aim of this study was to investigate tooth whitening efficacy and oral side effects during bleaching with Whitestrips® (WS) (6% hydrogen peroxide H2O2 gel) and Vivadent Vivastyle® (VS) (10% carbamide peroxide gel). Forty-seven subjects were included in this single blind, randomized, parallel group study. Application of WS was performed twice a day for 30 min. Trays filled with VS were worn for 60 min once a day. Tooth color was evaluated by measuring L*a*b* values before the study and after completion of the bleaching. Treatment tolerability was monitored throughout bleaching with an 8-week follow-up after completion of therapy. After 2 weeks both treatment groups demonstrated significant improvements in tooth color compared to baseline. A shift toward less yellow (−Δb) and brighter (+ΔL) tooth color was observed. Δb amounted to −1.69 ± 0.38 for WS and −1.20 ± 0.34 for VS (mean value ± SE). ΔL was +1.55 ± 0.41 for WS and +1.20 ± 0.37 for VS. There was no significant difference between the two systems. No significant differences between the two bleaching systems were recorded for clinically observed signs or reported symptoms. Gingival irritation was observed in 13%, reported tooth hypersensitivities in 22% and reported gum irritation in 20% of the total study population. At an 8-week follow-up visit no adverse effects were observed. Both WS and VS demonstrated significant and comparable levels of tooth color improvement after 2 weeks. Each treatment caused similar levels of transient oral side effects.
Literature
1.
go back to reference Attin T, Paque F, Ajam F, Lennon AM (2003) Review of the current status of tooth whitening with the walking bleach technique. Int Endod J 36:313–329PubMedCrossRef Attin T, Paque F, Ajam F, Lennon AM (2003) Review of the current status of tooth whitening with the walking bleach technique. Int Endod J 36:313–329PubMedCrossRef
2.
go back to reference Barnes DM, Kihn PW, Romberg E, George D, De Paola L, Medina E (1998) Clinical evaluation of a new carbamide peroxide tooth-whitening agent. Compend Contin Educ Dent 19:968–978PubMed Barnes DM, Kihn PW, Romberg E, George D, De Paola L, Medina E (1998) Clinical evaluation of a new carbamide peroxide tooth-whitening agent. Compend Contin Educ Dent 19:968–978PubMed
3.
go back to reference Christensen GJ (1997) Bleaching teeth: report of a survey. J Esthet Dent 10:16–20CrossRef Christensen GJ (1997) Bleaching teeth: report of a survey. J Esthet Dent 10:16–20CrossRef
4.
go back to reference Cohan S, Parkins FM (1970) Bleaching tetracycline-stained vital teeth. Oral Surg Oral Med Oral Pathol 29:465–471CrossRef Cohan S, Parkins FM (1970) Bleaching tetracycline-stained vital teeth. Oral Surg Oral Med Oral Pathol 29:465–471CrossRef
5.
go back to reference Commission Internationale de Léclairage (1971) Recommendations on uniform colour spaces. Colour difference equations. Psychometric colour terms. Bureau Central de la CIE, Paris, France, Suppl 2 to CIE pub 14 (E-13.1)/(TC-1.3), 1978 Commission Internationale de Léclairage (1971) Recommendations on uniform colour spaces. Colour difference equations. Psychometric colour terms. Bureau Central de la CIE, Paris, France, Suppl 2 to CIE pub 14 (E-13.1)/(TC-1.3), 1978
6.
go back to reference Cooper JS, Bokmeyer TJ, Bowles WH (1992) Penetration of the pulp chamber by carbamide peroxide bleaching agents. J Endod 18:315–317PubMedCrossRef Cooper JS, Bokmeyer TJ, Bowles WH (1992) Penetration of the pulp chamber by carbamide peroxide bleaching agents. J Endod 18:315–317PubMedCrossRef
7.
go back to reference Da Costa Filho LC, Da Costa CC, Soria ML, Taga R (2002) Effect of home bleaching and smoking on marginal gingival epithelium proliferation: a histologic study in women. J Oral Pathol Med 31:473–480PubMedCrossRef Da Costa Filho LC, Da Costa CC, Soria ML, Taga R (2002) Effect of home bleaching and smoking on marginal gingival epithelium proliferation: a histologic study in women. J Oral Pathol Med 31:473–480PubMedCrossRef
8.
go back to reference Douglas RD (1997) Precision of in vivo colourimetric assessments of teeth. J Prosthet Dent 77:464–470PubMedCrossRef Douglas RD (1997) Precision of in vivo colourimetric assessments of teeth. J Prosthet Dent 77:464–470PubMedCrossRef
9.
go back to reference Dunn JR (1998) Dentist-prescribed home bleaching: current status. Compend Contin Educ Dent 19:760–764PubMed Dunn JR (1998) Dentist-prescribed home bleaching: current status. Compend Contin Educ Dent 19:760–764PubMed
10.
go back to reference Ferrari M, Kugel G, Cagidiaco MC, Barker ML, Gerlach RW (2004) Clinical trial evaluating the peroxide concentration response of whitening strips over 28 days. Am J Dent 17:291–294PubMed Ferrari M, Kugel G, Cagidiaco MC, Barker ML, Gerlach RW (2004) Clinical trial evaluating the peroxide concentration response of whitening strips over 28 days. Am J Dent 17:291–294PubMed
11.
go back to reference Gegauff AG, Rosenstiel SF, Langhout KJ, Johnston WM (1993) Evaluating tooth colour change from carbamide peroxide gel. J Am Dent Assoc 124:65–72PubMed Gegauff AG, Rosenstiel SF, Langhout KJ, Johnston WM (1993) Evaluating tooth colour change from carbamide peroxide gel. J Am Dent Assoc 124:65–72PubMed
12.
go back to reference Gerlach RW, Zhou X (2001) Vital bleaching with whitening strips: summary of clinical research on effectiveness and tolerability. J Contemp Dent Pract 15:1–16 Gerlach RW, Zhou X (2001) Vital bleaching with whitening strips: summary of clinical research on effectiveness and tolerability. J Contemp Dent Pract 15:1–16
13.
go back to reference Gerlach RW, Gibb RD, Sagel PA (2000) A randomized clinical trial comparing a novel 5.3% hydrogen peroxide whitening strip to 10%, 15%, and 20% carbamide peroxide tray-based bleaching systems. Compend Contin Educ Dent Suppl 29:22–28 Gerlach RW, Gibb RD, Sagel PA (2000) A randomized clinical trial comparing a novel 5.3% hydrogen peroxide whitening strip to 10%, 15%, and 20% carbamide peroxide tray-based bleaching systems. Compend Contin Educ Dent Suppl 29:22–28
14.
go back to reference Gerlach RW, Barker ML, Sagel PA (2003) Objective and subjective whitening response of two self-directed bleaching systems. Am J Dent 15:7A–12A Gerlach RW, Barker ML, Sagel PA (2003) Objective and subjective whitening response of two self-directed bleaching systems. Am J Dent 15:7A–12A
15.
go back to reference Gerlach RW, He T, Zhou X (2003) Safety and tolerability of vital bleaching with whitening strips: evidence from 32 clinical trials. J Dent Res 82 (abstract 0078) Gerlach RW, He T, Zhou X (2003) Safety and tolerability of vital bleaching with whitening strips: evidence from 32 clinical trials. J Dent Res 82 (abstract 0078)
16.
go back to reference Gerlach RW, Zhou X, McMillan DA (2003) Safety of vital tooth bleaching with 6% hydrogen peroxide whitening strips: evidence from 18 clinical trials. J Dent Res 83 (abstract 1045) Gerlach RW, Zhou X, McMillan DA (2003) Safety of vital tooth bleaching with 6% hydrogen peroxide whitening strips: evidence from 18 clinical trials. J Dent Res 83 (abstract 1045)
17.
go back to reference Gonzalez-Ochoa JG, Nordahl I, Matis BA, Mjor IA (2003) Histological assessment of the dental pulp after bleaching. J Dent Res 82 (abstract 2480) Gonzalez-Ochoa JG, Nordahl I, Matis BA, Mjor IA (2003) Histological assessment of the dental pulp after bleaching. J Dent Res 82 (abstract 2480)
18.
go back to reference Hannig C, Zech R, Henze E, Dorr-Tolui R, Attin T (2003) Determination of peroxides in saliva—kinetics of peroxide release into saliva during home bleaching with Whitestrips and Vivastyle in vivo. Arch Oral Biol 48:559–568PubMedCrossRef Hannig C, Zech R, Henze E, Dorr-Tolui R, Attin T (2003) Determination of peroxides in saliva—kinetics of peroxide release into saliva during home bleaching with Whitestrips and Vivastyle in vivo. Arch Oral Biol 48:559–568PubMedCrossRef
19.
go back to reference Hannig C, Zech R, Henze E, Dreier S, Attin T (2005) Peroxide release into saliva from five different home bleaching systems in vivo. Am J Dent 18:13–18PubMed Hannig C, Zech R, Henze E, Dreier S, Attin T (2005) Peroxide release into saliva from five different home bleaching systems in vivo. Am J Dent 18:13–18PubMed
20.
go back to reference Hannig C, Willenbücher S, Becker K, Mahony C, Attin T (2006) Recovery of peroxides in saliva during home bleaching—influence of smoking. J Oral Rehabil 33:533–541PubMedCrossRef Hannig C, Willenbücher S, Becker K, Mahony C, Attin T (2006) Recovery of peroxides in saliva during home bleaching—influence of smoking. J Oral Rehabil 33:533–541PubMedCrossRef
21.
go back to reference Haywood VB, Heymann HO (1997) Nightguard vital bleaching. Quintessence Int 20:173–176 Haywood VB, Heymann HO (1997) Nightguard vital bleaching. Quintessence Int 20:173–176
22.
go back to reference Haywood VB, Leonard RH, Nelson CF, Brunson WD (1994) Effectiveness, side effects and long-term status of Nightguard vital bleaching. J Am Dent Assoc 125:1219–1226PubMed Haywood VB, Leonard RH, Nelson CF, Brunson WD (1994) Effectiveness, side effects and long-term status of Nightguard vital bleaching. J Am Dent Assoc 125:1219–1226PubMed
23.
go back to reference Haywood VB, Leonard RH, Dickinson GL (1997) Primarily research. Efficacy of six months of Nightguard vital bleaching of tetracycline-stained teeth. J Esthet Dent 9:13–19PubMedCrossRef Haywood VB, Leonard RH, Dickinson GL (1997) Primarily research. Efficacy of six months of Nightguard vital bleaching of tetracycline-stained teeth. J Esthet Dent 9:13–19PubMedCrossRef
24.
go back to reference Horn DJ, Bulan-Brady J, Hicks ML (1998) Sphere spectrophotometer versus human evaluation of tooth shade. J Endod 24:786–790PubMedCrossRef Horn DJ, Bulan-Brady J, Hicks ML (1998) Sphere spectrophotometer versus human evaluation of tooth shade. J Endod 24:786–790PubMedCrossRef
25.
go back to reference ICH (1997) Harmonised tripartite guideline for good clinical practice. Institute of Clinical Research, Maidenhead, UK ICH (1997) Harmonised tripartite guideline for good clinical practice. Institute of Clinical Research, Maidenhead, UK
26.
go back to reference Kugel G, Kastali S (2000) Tooth-whitening efficacy and safety: a randomized and controlled clinical trial. Compend Contin Educ Dent Suppl 29:16–21 Kugel G, Kastali S (2000) Tooth-whitening efficacy and safety: a randomized and controlled clinical trial. Compend Contin Educ Dent Suppl 29:16–21
27.
go back to reference Lange DE, Plagmann HC, Eenboom A, Promesberger A (1977) Clinical evaluation methods for analysis of oral hygienic conditions (text in German). Dtsch Zahnärztl Z 32:44–51PubMed Lange DE, Plagmann HC, Eenboom A, Promesberger A (1977) Clinical evaluation methods for analysis of oral hygienic conditions (text in German). Dtsch Zahnärztl Z 32:44–51PubMed
28.
go back to reference Leonard RH, Haywood VB, Philipps C (1997) Risk factors for developing tooth sensitivity and gingival irritation associated with Nightguard vital bleaching. Quintessence 28:527–534 Leonard RH, Haywood VB, Philipps C (1997) Risk factors for developing tooth sensitivity and gingival irritation associated with Nightguard vital bleaching. Quintessence 28:527–534
29.
go back to reference Leonard RH Jr, Haywood VB, Eagle JC, Garland GE, Caplan DJ, Matthews KP, Tart ND (1999) Nightguard vital bleaching of tetracycline-stained teeth: 54 months post treatment. J Esthet Dent 11:265–277PubMedCrossRef Leonard RH Jr, Haywood VB, Eagle JC, Garland GE, Caplan DJ, Matthews KP, Tart ND (1999) Nightguard vital bleaching of tetracycline-stained teeth: 54 months post treatment. J Esthet Dent 11:265–277PubMedCrossRef
30.
go back to reference McMillan DA, Gibb RD, Gerlach RW (2001) Impact of increasing hydrogen peroxide concentration on bleaching strip efficacy and tolerability. J Dent Res 80 (abstract 1102) McMillan DA, Gibb RD, Gerlach RW (2001) Impact of increasing hydrogen peroxide concentration on bleaching strip efficacy and tolerability. J Dent Res 80 (abstract 1102)
31.
go back to reference Nathanson D (1997) Vital tooth bleaching: sensibility and pulpal considerations. J Am Dent Assoc 128:S41–S44 Nathanson D (1997) Vital tooth bleaching: sensibility and pulpal considerations. J Am Dent Assoc 128:S41–S44
32.
go back to reference Niedermann R, Tantraphol MC, Slinin P, Hayes C, Conway S (2000) Effectiveness of dentist-prescribed, home-applied tooth whitening. A meta analysis. J Contemp Dent Pract 15:20–36 Niedermann R, Tantraphol MC, Slinin P, Hayes C, Conway S (2000) Effectiveness of dentist-prescribed, home-applied tooth whitening. A meta analysis. J Contemp Dent Pract 15:20–36
33.
go back to reference Pohjola RM, Browning WD, Hackmann ST, Myers ML, Downey MC (2002) Sensitivity and tooth whitening agents. J Esthet Restor Dent 14:85–91PubMedCrossRef Pohjola RM, Browning WD, Hackmann ST, Myers ML, Downey MC (2002) Sensitivity and tooth whitening agents. J Esthet Restor Dent 14:85–91PubMedCrossRef
34.
go back to reference Sagel PA, Jeffers ME, Gibb RD, Gerlach RW (2002) Overview of a professional tooth-whitening system containing 6.5% hydrogen peroxide whitening strips. Compend Contin Educ Dent 23:9–15PubMed Sagel PA, Jeffers ME, Gibb RD, Gerlach RW (2002) Overview of a professional tooth-whitening system containing 6.5% hydrogen peroxide whitening strips. Compend Contin Educ Dent 23:9–15PubMed
35.
go back to reference Saxer UP, Mühlemann HR (1975) Motivation and instruction (text in German). Schweiz Monatsschr Zahnmed 85:905 Saxer UP, Mühlemann HR (1975) Motivation and instruction (text in German). Schweiz Monatsschr Zahnmed 85:905
36.
go back to reference Thitinanthapan W, Satomont P, Vongsavan N (1999) In vitro penetration of the pulp chamber by three brands of carbamide peroxide. J Esthet Dent 11:259–264PubMedCrossRef Thitinanthapan W, Satomont P, Vongsavan N (1999) In vitro penetration of the pulp chamber by three brands of carbamide peroxide. J Esthet Dent 11:259–264PubMedCrossRef
37.
go back to reference Tipton DA, Braxton SD, Dabbous MK (1995) Role of saliva and salivary components as modulators of bleaching agents toxicity to human gingival fibroblasts in vitro. J Periodontal 66:766–774 Tipton DA, Braxton SD, Dabbous MK (1995) Role of saliva and salivary components as modulators of bleaching agents toxicity to human gingival fibroblasts in vitro. J Periodontal 66:766–774
38.
go back to reference Tung FF, Goldstein GR, Jang S, Hittelman E (2002) The repeatability of an intraoral dental colourimeter. J Prosthet Dent 88:585–590PubMedCrossRef Tung FF, Goldstein GR, Jang S, Hittelman E (2002) The repeatability of an intraoral dental colourimeter. J Prosthet Dent 88:585–590PubMedCrossRef
39.
go back to reference Zhou X, ML Barker, Gibb RD, Gerlach RW (2002) Impact of behavioral, clinical and demographic parameters on whitening response: evidence from 18 clinical trials. J Dent Res 81 (abstract 1965) Zhou X, ML Barker, Gibb RD, Gerlach RW (2002) Impact of behavioral, clinical and demographic parameters on whitening response: evidence from 18 clinical trials. J Dent Res 81 (abstract 1965)
Metadata
Title
Efficacy and tolerability of two home bleaching systems having different peroxide delivery
Authors
Christian Hannig
Dirk Lindner
Thomas Attin
Publication date
01-12-2007
Publisher
Springer-Verlag
Published in
Clinical Oral Investigations / Issue 4/2007
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-007-0128-x

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