Skip to main content
Top
Published in: Surgical Endoscopy 6/2015

01-06-2015

Efficacy and adverse events of laparoscopic gastrostomy placement in children: results of a large cohort study

Authors: Josephine Franken, Femke A. Mauritz, Nutnicha Suksamanapun, Caroline C. C. Hulsker, David C. van der Zee, Maud Y. A. van Herwaarden-Lindeboom

Published in: Surgical Endoscopy | Issue 6/2015

Login to get access

Abstract

Introduction

A gastrostomy placement is frequently performed in pediatric patients who require long-term enteral tube feeding. However, data on efficacy, perioperative complications and postoperative gastroesophageal reflux (GER) after laparoscopic gastrostomy (LAG) placement is limited.
The aim of this study is to evaluate long-term efficacy and adverse events after LAG in a large cohort and determine whether routine preoperative 24-h pH monitoring should be used to predict postoperative GER.

Method

A retrospective observational cohort study was performed including 300 patients (75 % neurologically impaired) that underwent LAG.

Results

After a median follow-up of 2.63 years, feeding was successful in 95.9 % of patients. Weight-for-length z-scores significantly increased (p < 0.0005). Major complications were seen in only 6 patients (2.0 %), but minor complications occurred frequently (73.6 %). Overall incidence of GER remained unchanged after LAG. Sensitivity and specificity of preoperative pH monitoring were 17.5 and 76.9 %, respectively.

Conclusion

LAG placement in pediatric patients leads to successful feeding in 96 % of patients and serious adverse events are rare. However, the minor complication rate is high. Overall incidence of GER does not increase after LAG. Preoperative 24-h pH monitoring is not a reliable tool to predict postoperative GER. This invasive investigation technique should therefore not be routinely performed.
Literature
1.
go back to reference Srinivasan R, Irvine T, Dalzell M (2009) Indications for PEG and procedure-related outcome. J Pediatr Gastroenterol 49:584–588CrossRef Srinivasan R, Irvine T, Dalzell M (2009) Indications for PEG and procedure-related outcome. J Pediatr Gastroenterol 49:584–588CrossRef
2.
go back to reference Fortunato JE, Troy AL, Cuffari C, Davis JE, Loza MJ, Oliva-Hemker M, Schwarz KB (2010) Outcome after PEG in children and young adults. J Pediatr Gastroenterol Nutr 50:390–393PubMed Fortunato JE, Troy AL, Cuffari C, Davis JE, Loza MJ, Oliva-Hemker M, Schwarz KB (2010) Outcome after PEG in children and young adults. J Pediatr Gastroenterol Nutr 50:390–393PubMed
3.
go back to reference Khattak IU, Kimber C, Kiely EM, Spitz L (1998) PEG in paediatric practice: complications and outcome. J Pediatr Surg 33:67–72CrossRefPubMed Khattak IU, Kimber C, Kiely EM, Spitz L (1998) PEG in paediatric practice: complications and outcome. J Pediatr Surg 33:67–72CrossRefPubMed
4.
go back to reference Tomicic JT, Luks FI, Shalon L, Tracy TF (2002) LAG in infants and children. Eur J Pediatr Surg 12:107–110CrossRefPubMed Tomicic JT, Luks FI, Shalon L, Tracy TF (2002) LAG in infants and children. Eur J Pediatr Surg 12:107–110CrossRefPubMed
5.
go back to reference Wragg RC, Salminen H, Pachl M, Singh M, Lander A, Jester I, Parikh D, Jawaheer G (2012) Gastrostomy insertion in the 21st century: PEG or laparoscopic? Report from a large single-centre series. Pediatr Surg Int 28:443–448CrossRefPubMed Wragg RC, Salminen H, Pachl M, Singh M, Lander A, Jester I, Parikh D, Jawaheer G (2012) Gastrostomy insertion in the 21st century: PEG or laparoscopic? Report from a large single-centre series. Pediatr Surg Int 28:443–448CrossRefPubMed
6.
go back to reference Zamakhshary M, Jamal M, Blair GK, Murphy JJ, Webber EM, Skarsgard ED (2005) Laparoscopic vs PEG tube insertion: a new pediatric gold standard? J Pediatr Surg 40:859–862CrossRefPubMed Zamakhshary M, Jamal M, Blair GK, Murphy JJ, Webber EM, Skarsgard ED (2005) Laparoscopic vs PEG tube insertion: a new pediatric gold standard? J Pediatr Surg 40:859–862CrossRefPubMed
7.
go back to reference Rempel GR, Colwell SO, Nelson RP (1988) Growth in children with cerebral palsy fed via gastrostomy. Pediatrics 82:857–862PubMed Rempel GR, Colwell SO, Nelson RP (1988) Growth in children with cerebral palsy fed via gastrostomy. Pediatrics 82:857–862PubMed
8.
go back to reference Corwin DS, Isaacs JS, Georgeson KE, Bartolucci AA, Cloud HH, Craig CB (1996) Weight and length increases in children after gastrostomy placement. J Am Diet Assoc 96:874–879CrossRefPubMed Corwin DS, Isaacs JS, Georgeson KE, Bartolucci AA, Cloud HH, Craig CB (1996) Weight and length increases in children after gastrostomy placement. J Am Diet Assoc 96:874–879CrossRefPubMed
9.
go back to reference Samson-Fang L, Butler C, O’Donnell M (2003) Effects of gastrostomy feeding in children with cerebral palsy: an AACPDM evidence report. Dev Med Child Neurol 45:415–426CrossRefPubMed Samson-Fang L, Butler C, O’Donnell M (2003) Effects of gastrostomy feeding in children with cerebral palsy: an AACPDM evidence report. Dev Med Child Neurol 45:415–426CrossRefPubMed
10.
go back to reference Brewster BD, Weil BR, Ladd AP (2012) Prospective determination of PEG complication rates in children: still a safe procedure. Surgery 152:714–719CrossRefPubMed Brewster BD, Weil BR, Ladd AP (2012) Prospective determination of PEG complication rates in children: still a safe procedure. Surgery 152:714–719CrossRefPubMed
11.
go back to reference Crosby J, Duerksen D (2005) A retrospective survey of tube-related complications in patients receiving long-term home enteral nutrition. Dig Dis Sci 50:1712–1717CrossRefPubMed Crosby J, Duerksen D (2005) A retrospective survey of tube-related complications in patients receiving long-term home enteral nutrition. Dig Dis Sci 50:1712–1717CrossRefPubMed
12.
go back to reference Mollitt DL, Golladay ES, Seibert JJ (1985) Symptomatic gastroesophageal reflux following gastrostomy in neurologically impaired patients. Pediatrics 75:1124–1126PubMed Mollitt DL, Golladay ES, Seibert JJ (1985) Symptomatic gastroesophageal reflux following gastrostomy in neurologically impaired patients. Pediatrics 75:1124–1126PubMed
13.
go back to reference Sulaeman E, Udall JN Jr, Brown RF, Mannick EE, Loe WA, Hill CB, Schmidt-Sommerfeld E (1998) Gastroesophageal reflux and Nissen fundoplication following PEG in children. J Pediatr Gastroenterol Nutr 26:269–273CrossRefPubMed Sulaeman E, Udall JN Jr, Brown RF, Mannick EE, Loe WA, Hill CB, Schmidt-Sommerfeld E (1998) Gastroesophageal reflux and Nissen fundoplication following PEG in children. J Pediatr Gastroenterol Nutr 26:269–273CrossRefPubMed
14.
go back to reference Wilson GJ, van der Zee DC, Bax NM (2006) Endoscopic gastrostomy placement in the child with gastroesophageal reflux: is concomitant ARS indicated? J Pediatr Surg 41:1441–1445CrossRefPubMed Wilson GJ, van der Zee DC, Bax NM (2006) Endoscopic gastrostomy placement in the child with gastroesophageal reflux: is concomitant ARS indicated? J Pediatr Surg 41:1441–1445CrossRefPubMed
15.
go back to reference Razeghi S, Lang T, Behrens R (2002) Influence of PEG on gastroesophageal reflux: a prospective study in 68 children. J Pediatr Gastroenterol Nutr 35:27–30CrossRefPubMed Razeghi S, Lang T, Behrens R (2002) Influence of PEG on gastroesophageal reflux: a prospective study in 68 children. J Pediatr Gastroenterol Nutr 35:27–30CrossRefPubMed
16.
17.
go back to reference TNO Groeicalculator voor de vijfde landelijke Groeistudie. 2013. Ref Type : Internet Communication TNO Groeicalculator voor de vijfde landelijke Groeistudie. 2013. Ref Type : Internet Communication
18.
go back to reference Richter JE, Bradley LA, DeMeester T, Wu WC (1992) Normal 24-h ambulatory esophageal pH values. Influence of study center, pH electrode, age and gender. Dig Dis Sci 37:849–856CrossRefPubMed Richter JE, Bradley LA, DeMeester T, Wu WC (1992) Normal 24-h ambulatory esophageal pH values. Influence of study center, pH electrode, age and gender. Dig Dis Sci 37:849–856CrossRefPubMed
19.
go back to reference Smout AJ, Breedijk M, van der Zouw C, Akkermans LM (1989) Physiological gastroesophageal reflux and esophageal motor activity studied with a new system for 24-h recording and automated analysis. Dig Dis Sci 34:372–378CrossRefPubMed Smout AJ, Breedijk M, van der Zouw C, Akkermans LM (1989) Physiological gastroesophageal reflux and esophageal motor activity studied with a new system for 24-h recording and automated analysis. Dig Dis Sci 34:372–378CrossRefPubMed
20.
go back to reference Kang A, Zamora SA, Scott RB, Parsons HG (1998) Catch-up growth in children treated with home enteral nutrition. Pediatrics 102:951–955CrossRefPubMed Kang A, Zamora SA, Scott RB, Parsons HG (1998) Catch-up growth in children treated with home enteral nutrition. Pediatrics 102:951–955CrossRefPubMed
21.
go back to reference Walker SP, Golden MH (1988) Growth in length of children recovering from severe malnutrition. Eur J Clin Nutr 42:395–404PubMed Walker SP, Golden MH (1988) Growth in length of children recovering from severe malnutrition. Eur J Clin Nutr 42:395–404PubMed
22.
go back to reference Lantz M, Hultin LH, Arnbjornsson E (2010) Literature review comparing laparoscopic and percutaneous endoscopic gastrostomies in a pediatric population. Int J Pediatr 2010:507616CrossRefPubMedCentralPubMed Lantz M, Hultin LH, Arnbjornsson E (2010) Literature review comparing laparoscopic and percutaneous endoscopic gastrostomies in a pediatric population. Int J Pediatr 2010:507616CrossRefPubMedCentralPubMed
23.
go back to reference Arnbjornsson E, Larsson LT, Lindhagen T (1999) Complications of laparoscopy-aided gastrostomies in pediatric practice. J Pediatr Surg 34:1843–1846CrossRefPubMed Arnbjornsson E, Larsson LT, Lindhagen T (1999) Complications of laparoscopy-aided gastrostomies in pediatric practice. J Pediatr Surg 34:1843–1846CrossRefPubMed
24.
go back to reference Thorne SE, Radford MJ (1998) A comparative longitudinal study of gastrostomy devices in children. West J Nurs Res 20:145–159 discussion 159–65CrossRefPubMed Thorne SE, Radford MJ (1998) A comparative longitudinal study of gastrostomy devices in children. West J Nurs Res 20:145–159 discussion 159–65CrossRefPubMed
25.
go back to reference Lintula H, Juvonen P, Hämynen I, Heikkinen M, Eskelinen M (2013) Severe gastro-oesophageal reflux necessitating fundoplication after percutaneous endoscopic and open gastrostomy in children. Langenbecks Arch Surg 398:703–707CrossRefPubMed Lintula H, Juvonen P, Hämynen I, Heikkinen M, Eskelinen M (2013) Severe gastro-oesophageal reflux necessitating fundoplication after percutaneous endoscopic and open gastrostomy in children. Langenbecks Arch Surg 398:703–707CrossRefPubMed
26.
go back to reference Noble LJ, Dalzell AM, El-Matary W (2012) The relationship between PEG and gastro-oesophageal reflux disease in children: a systematic review. Surg Endosc 26:2504–2512CrossRefPubMed Noble LJ, Dalzell AM, El-Matary W (2012) The relationship between PEG and gastro-oesophageal reflux disease in children: a systematic review. Surg Endosc 26:2504–2512CrossRefPubMed
27.
go back to reference Hassall E (2005) Decisions in diagnosing and managing chronic gastroesophageal reflux disease in children. J Pediatr 146:S3–S12CrossRefPubMed Hassall E (2005) Decisions in diagnosing and managing chronic gastroesophageal reflux disease in children. J Pediatr 146:S3–S12CrossRefPubMed
28.
go back to reference Vandenplas Y, Sacre-Smits L (1987) Continuous 24-h esophageal pH monitoring in 285 asymptomatic infants 0–15 months old. J Pediatr Gastroenterol Nutr 6:220–224CrossRefPubMed Vandenplas Y, Sacre-Smits L (1987) Continuous 24-h esophageal pH monitoring in 285 asymptomatic infants 0–15 months old. J Pediatr Gastroenterol Nutr 6:220–224CrossRefPubMed
29.
go back to reference Vandenplas Y, Goyvaerts H, Helven R, Sacre L (1991) Gastroesophageal reflux, as measured by 24-h pH monitoring, in 509 healthy infants screened for risk of sudden infant death syndrome. Pediatrics 88:834–840PubMed Vandenplas Y, Goyvaerts H, Helven R, Sacre L (1991) Gastroesophageal reflux, as measured by 24-h pH monitoring, in 509 healthy infants screened for risk of sudden infant death syndrome. Pediatrics 88:834–840PubMed
Metadata
Title
Efficacy and adverse events of laparoscopic gastrostomy placement in children: results of a large cohort study
Authors
Josephine Franken
Femke A. Mauritz
Nutnicha Suksamanapun
Caroline C. C. Hulsker
David C. van der Zee
Maud Y. A. van Herwaarden-Lindeboom
Publication date
01-06-2015
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 6/2015
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-014-3839-5

Other articles of this Issue 6/2015

Surgical Endoscopy 6/2015 Go to the issue