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01-09-2016 | Original Research

Effects on cardiovascular risk factors of weight losses limited to 5–10 %

Authors: Joshua D. Brown, Ph.D., Joanna Buscemi, Ph.D., Vanessa Milsom, Ph.D., Robert Malcolm, M.D., Patrick M. O’Neil, Ph.D.

Published in: Translational Behavioral Medicine | Issue 3/2016

Abstract

Little is known about the cardiovascular effects of modest weight loss. To determine whether weight losses limited to 5–10 % are sufficient to produce cardiovascular health benefits, data from 401 overweight and obese adults who enrolled in a behavioral weight loss program from 2003 to 2011 were analyzed. Primary outcomes were changes in fasting glucose, triglycerides, and cholesterol. Patients who lost 5–10 % showed significant reductions in triglycerides, total cholesterol, and low-density lipoprotein (LDL) cholesterol. Patients who lost >10 % experienced significantly greater improvements in triglycerides, total cholesterol, and LDL cholesterol than patients losing less. For higher-risk patients, those who lost 5–10 % significantly reduced fasting glucose, triglycerides, and total cholesterol; those who lost >10 % improved on all risk factors (except HDL cholesterol) and to a significantly greater degree than those losing less. Five to 10 % weight losses produced improvements in cardiovascular risk factors, but greater weight losses were associated with even greater improvement.

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Title: Effects on cardiovascular risk factors of weight losses limited to 5–10 %
Authors: Joshua D. Brown, Ph.D.
Joanna Buscemi, Ph.D.
Vanessa Milsom, Ph.D.
Robert Malcolm, M.D.
Patrick M. O’Neil, Ph.D.
Publication date: 01-09-2016
Publisher: Springer US
Published in: Translational Behavioral Medicine / Issue 3/2016
Print ISSN: 1869-6716
Electronic ISSN: 1613-9860
DOI: https://doi.org/10.1007/s13142-015-0353-9

At a glance: The STEP trials

Springer Medicine

Effects on cardiovascular risk factors of weight losses limited to 5–10 %

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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