Skip to main content
Top
Published in: Sport Sciences for Health 2/2018

01-08-2018 | Original Article

Effects of a single session of high-intensity interval exercise and moderate-intensity continuous exercise on biochemical cardiovascular risk factors in obese males

Authors: Ana Paula Trussardi Fayh, Victor Araújo Ferreira Matos, Daniel Costa de Souza, Victor Oliveira Albuquerque dos Santos, Cristiane da Silva Ramos Marinho, Alexandre Coelho Serquiz, Rogerio Friedman, Eduardo Caldas Costa

Published in: Sport Sciences for Health | Issue 2/2018

Login to get access

Abstract

Background

Few have analyzed the effects of different intensities of acute physical exercise on biochemical parameters of cardiovascular disease.

Aim

To examine the acute effects of high-intensity interval exercise (HIIE) and moderate-intensity continuous exercise (MICE) on biochemical cardiovascular markers in obese male adults.

Materials and methods

Twelve sedentary obese male subjects (28.4 ± 2.6 years old, BMI 35.5 ± 4.5 kg/m2, 39.8 ± 2.2% body fat) took part in this randomized, cross-over clinical trial. Three experimental sessions, at 7-day intervals, in random order, were carried out: (1) HIIE: 10 × 60 s at ~ 90% of maximal peak velocity, interspersed by 60 s of active recovery, (2) MICE: 20 min at ~ 70% of maximum heart rate, and (3) control session. A standardized breakfast was offered before the exercise sessions. Biochemical markers of cardiovascular risk (glycemia, total cholesterol and fractions, triglycerides, hepatic enzymes and nitrogen scores) were assessed pre-exercise, immediately post-exercise, and 60 min post-exercise.

Results

In general, no significant interaction was observed, with the exception of creatinine, that had a statistically significant two-way interaction between time and condition, F(4,40) = 5.053, p < 0.05. There was a statistically significant two-way effect in time, F(2,22) = 5.906, p < 0.05 for AST, and a statistically significant two-way effect in treatment, F(2,22) = 13.477, p < 0.05 for glucose.

Conclusion

In this context, HIIE seems to be a safe alternative to MICE for the prevention and management of obesity, as well as the disorders observed in this population.
Literature
2.
go back to reference Burgess E, Hassmén P, Pumpa KL (2017) Determinants of adherence to lifestyle intervention in adults with obesity: a systematic review. Clin Obes 7:123–135CrossRefPubMed Burgess E, Hassmén P, Pumpa KL (2017) Determinants of adherence to lifestyle intervention in adults with obesity: a systematic review. Clin Obes 7:123–135CrossRefPubMed
3.
go back to reference Casazza K, Fontaine KR, Astrup A, Birch LL, Brown AW, Bohan Brown MM et al (2013) Myths, presumptions and facts about obesity. N Engl J Med 368:446–454CrossRefPubMedPubMedCentral Casazza K, Fontaine KR, Astrup A, Birch LL, Brown AW, Bohan Brown MM et al (2013) Myths, presumptions and facts about obesity. N Engl J Med 368:446–454CrossRefPubMedPubMedCentral
4.
go back to reference Garcia-Hermoso A, Cerrilo-Hurbina AJ, Herrera-Valenzuela T, Cristi-Montero C, Saavedra JM, Martinez VV (2016) Is high-intensity interval training more effective on improving cardiometabolic risk and aerobic capacity than other forms of exercise in overweight and obese youth? A meta-analysis. Obes Rev 17:531–540CrossRefPubMed Garcia-Hermoso A, Cerrilo-Hurbina AJ, Herrera-Valenzuela T, Cristi-Montero C, Saavedra JM, Martinez VV (2016) Is high-intensity interval training more effective on improving cardiometabolic risk and aerobic capacity than other forms of exercise in overweight and obese youth? A meta-analysis. Obes Rev 17:531–540CrossRefPubMed
5.
go back to reference Marchesini G, Moscatiello S, Di Domizio S, Forlani G (2008) Obesity-associated liver disease. J Clin Endocrinol Metabol 93:s74–s80CrossRef Marchesini G, Moscatiello S, Di Domizio S, Forlani G (2008) Obesity-associated liver disease. J Clin Endocrinol Metabol 93:s74–s80CrossRef
6.
go back to reference Bellentani S, Saccoccio G, Masutti F, Croce LS, Brandi G, Sasso F, Cristanini G, Tiribelli C (2000) Prevalence of and risk factors for hepatic steatosis in Northern Italy. Ann Intern Med 132:112–117CrossRefPubMed Bellentani S, Saccoccio G, Masutti F, Croce LS, Brandi G, Sasso F, Cristanini G, Tiribelli C (2000) Prevalence of and risk factors for hepatic steatosis in Northern Italy. Ann Intern Med 132:112–117CrossRefPubMed
7.
go back to reference Kovesdy CP, Furth SL, Zoccali C, On behalf of the World Kidney Day Steering Committee (2017) Obesity and kidney disease: hidden consequences of the epidemic. Can J Kidney Health Dis 4:1–10CrossRef Kovesdy CP, Furth SL, Zoccali C, On behalf of the World Kidney Day Steering Committee (2017) Obesity and kidney disease: hidden consequences of the epidemic. Can J Kidney Health Dis 4:1–10CrossRef
8.
go back to reference World Health Organization (2010) WHO global recommendations on physical activity for health. World Health Organization, Geneva World Health Organization (2010) WHO global recommendations on physical activity for health. World Health Organization, Geneva
9.
go back to reference American College of Sports Medicine (2009) ACSM’s guidelines for exercise testing and prescription, 8th edn. Williams & Wilkins, New York American College of Sports Medicine (2009) ACSM’s guidelines for exercise testing and prescription, 8th edn. Williams & Wilkins, New York
10.
go back to reference Batacan RB Jr, Duncan MJ, Dalbo VJ, Tucker PS, Fenning AS (2017) Effects of high-intensity interval training on cardiometabolic health: a systematic review and meta-analysis of intervention studies. Br J Sports Med 51:494–503CrossRefPubMed Batacan RB Jr, Duncan MJ, Dalbo VJ, Tucker PS, Fenning AS (2017) Effects of high-intensity interval training on cardiometabolic health: a systematic review and meta-analysis of intervention studies. Br J Sports Med 51:494–503CrossRefPubMed
11.
go back to reference Emadian A, Thompson JL (2017) A mixed-methods examination of physical activity and sedentary time in overweight and obese South Asian men living in the United Kingdom. Int J Environ Res Public Health 14:E348CrossRefPubMed Emadian A, Thompson JL (2017) A mixed-methods examination of physical activity and sedentary time in overweight and obese South Asian men living in the United Kingdom. Int J Environ Res Public Health 14:E348CrossRefPubMed
12.
go back to reference Fisher G, Brown AW, Brown MMB, Alcorn A, Noles C, Winwood L et al (2015) High intensity interval- vs moderate intensity- training for improving cardiometabolic health in overweight or obese males: a randomized controlled trial. PLoS ONE 10:e0138853CrossRefPubMedPubMedCentral Fisher G, Brown AW, Brown MMB, Alcorn A, Noles C, Winwood L et al (2015) High intensity interval- vs moderate intensity- training for improving cardiometabolic health in overweight or obese males: a randomized controlled trial. PLoS ONE 10:e0138853CrossRefPubMedPubMedCentral
13.
go back to reference Racil G, Ben Ounis O, Hammouda O, Kallel A, Zouhal H, Chamari K et al (2013) Effects of high vs moderate exercise intensity during interval training on lipids and adiponectin levels in obese young females. Eur J Appl Physiol 113:2531–2540CrossRefPubMed Racil G, Ben Ounis O, Hammouda O, Kallel A, Zouhal H, Chamari K et al (2013) Effects of high vs moderate exercise intensity during interval training on lipids and adiponectin levels in obese young females. Eur J Appl Physiol 113:2531–2540CrossRefPubMed
14.
go back to reference Racil G, Coquart JB, Elmontassar W, Haddad M, Goebel R, Chaouachi A et al (2016) Greater effects of high-compared with moderate-intensity interval training on cardio-metabolic variables, blood leptin concentration and ratings of perceived exertion in obese adolescent females. Biol Sport 33:145–152CrossRefPubMedPubMedCentral Racil G, Coquart JB, Elmontassar W, Haddad M, Goebel R, Chaouachi A et al (2016) Greater effects of high-compared with moderate-intensity interval training on cardio-metabolic variables, blood leptin concentration and ratings of perceived exertion in obese adolescent females. Biol Sport 33:145–152CrossRefPubMedPubMedCentral
15.
go back to reference Ciolac EG, Bocchi EA, Bortolotto LA, Carvalho VO, Greve J (2010) Effects of high-intensity aerobic interval training vs. moderate exercise on hemodynamic, metabolic and neuro-humoral abnormalities of young normotensive women at high familial risk for hypertension. Hypertension 33:836–843 Ciolac EG, Bocchi EA, Bortolotto LA, Carvalho VO, Greve J (2010) Effects of high-intensity aerobic interval training vs. moderate exercise on hemodynamic, metabolic and neuro-humoral abnormalities of young normotensive women at high familial risk for hypertension. Hypertension 33:836–843
16.
go back to reference Wisløff U, Støylen A, Loennechen JP, Bruvold M, Rognmo Ø, Haram PM et al (2007) Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart. Hypertens Res 15:3086–3095 Wisløff U, Støylen A, Loennechen JP, Bruvold M, Rognmo Ø, Haram PM et al (2007) Superior cardiovascular effect of aerobic interval training versus moderate continuous training in heart. Hypertens Res 15:3086–3095
17.
go back to reference Weston KS, Wisløff U, Coombes JS (2014) High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis. Br J Sports Med 48:1227–1234CrossRefPubMed Weston KS, Wisløff U, Coombes JS (2014) High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis. Br J Sports Med 48:1227–1234CrossRefPubMed
18.
go back to reference Marchesini G, Moscatiello S, Di Domizio S, Forlani G (2008) Obesity-associated liver disease. J Clin Endocrinol Metabol 93:S74–S80CrossRef Marchesini G, Moscatiello S, Di Domizio S, Forlani G (2008) Obesity-associated liver disease. J Clin Endocrinol Metabol 93:S74–S80CrossRef
19.
go back to reference Mann S, Beedie C, Jimenez A (2014) Differential effects of aerobic exercise, resistance training and combined exercise modalities on cholesterol and the lipid profile: review, synthesis and recommendations. Sports Med 44:211–221CrossRefPubMed Mann S, Beedie C, Jimenez A (2014) Differential effects of aerobic exercise, resistance training and combined exercise modalities on cholesterol and the lipid profile: review, synthesis and recommendations. Sports Med 44:211–221CrossRefPubMed
20.
go back to reference Godman J, Thomas S, Burr JF (2013) Cardiovascular risks of physical activity in apparently healthy individuals. Risk evaluation for exercise clearance and prescription. Can Fam Phys 59:46–49 Godman J, Thomas S, Burr JF (2013) Cardiovascular risks of physical activity in apparently healthy individuals. Risk evaluation for exercise clearance and prescription. Can Fam Phys 59:46–49
21.
go back to reference American Diabetes Association (2012) Standards of medical care in diabetes—2012. Diabetes Care 35:S11–S63CrossRef American Diabetes Association (2012) Standards of medical care in diabetes—2012. Diabetes Care 35:S11–S63CrossRef
22.
go back to reference Marliss EB, Vranic M (2002) Intense exercise has unique effects on both insulin release and its roles in glucoregulation: implications for diabetes. Diabetes 51:S271–S283CrossRefPubMed Marliss EB, Vranic M (2002) Intense exercise has unique effects on both insulin release and its roles in glucoregulation: implications for diabetes. Diabetes 51:S271–S283CrossRefPubMed
23.
go back to reference Thomas D, Erdman K, Burke L, American College of Sports Medicine (2016) Joint position statement: nutrition and athletic performance. Med Sci Sport Exerc 48:543–568 Thomas D, Erdman K, Burke L, American College of Sports Medicine (2016) Joint position statement: nutrition and athletic performance. Med Sci Sport Exerc 48:543–568
24.
go back to reference Frazão DT, De Farias LF, Dantas TCB, Krinski K, Elsangedy HM, Prestes J et al (2016) Feeling of pleasure to high-intensity interval exercise is dependent of the number of work bouts and physical activity status. PLoS ONE 1:153986 Frazão DT, De Farias LF, Dantas TCB, Krinski K, Elsangedy HM, Prestes J et al (2016) Feeling of pleasure to high-intensity interval exercise is dependent of the number of work bouts and physical activity status. PLoS ONE 1:153986
25.
go back to reference Friedewald W, Levi R, Fredrickson D (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499–502PubMed Friedewald W, Levi R, Fredrickson D (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18:499–502PubMed
26.
go back to reference Alkahtani SA, King NA, Hills AP, Byrne NM (2013) Effect of interval training intensity on fat oxidation, blood lactate and the rate of perceived exertion in obese men. Springerplus 2:1–10CrossRef Alkahtani SA, King NA, Hills AP, Byrne NM (2013) Effect of interval training intensity on fat oxidation, blood lactate and the rate of perceived exertion in obese men. Springerplus 2:1–10CrossRef
27.
go back to reference Matos VAF, de Souza DC, Browne RAV, dos Santos VOA, Costa EC, Fayh APT (2017) Acute effect of high-intensity interval exercise and moderate-intensity continuous exercise on appetite in overweight/obese males: a pilot study. Sport Sci Heal 13:403–410CrossRef Matos VAF, de Souza DC, Browne RAV, dos Santos VOA, Costa EC, Fayh APT (2017) Acute effect of high-intensity interval exercise and moderate-intensity continuous exercise on appetite in overweight/obese males: a pilot study. Sport Sci Heal 13:403–410CrossRef
28.
go back to reference Hellsten Y, Richter EA, Kiens B, Bangsbo J (1999) AMP deamination and purine exchange in human skeletal muscle during and after intense exercise. J Physiol 520:909–920CrossRefPubMedPubMedCentral Hellsten Y, Richter EA, Kiens B, Bangsbo J (1999) AMP deamination and purine exchange in human skeletal muscle during and after intense exercise. J Physiol 520:909–920CrossRefPubMedPubMedCentral
29.
go back to reference Morales AP, Maciel RN, Jorge FS, Neto NTA, de Cordeiro D, Viana MAS et al (2013) Alterações dos níveis séricos de creatinina, ácido úrico, creatina kinase e da taxa de filtração glomerular em corredores de “rua”. Rev Bras Cineantropometria Desempenho Hum 15:71–81 Morales AP, Maciel RN, Jorge FS, Neto NTA, de Cordeiro D, Viana MAS et al (2013) Alterações dos níveis séricos de creatinina, ácido úrico, creatina kinase e da taxa de filtração glomerular em corredores de “rua”. Rev Bras Cineantropometria Desempenho Hum 15:71–81
30.
go back to reference Kessler HS, Sisson SB, Short KR (2012) The potential for high-intensity interval training to reduce cardiometabolic disease risk. Sports Med 42:489–509CrossRefPubMed Kessler HS, Sisson SB, Short KR (2012) The potential for high-intensity interval training to reduce cardiometabolic disease risk. Sports Med 42:489–509CrossRefPubMed
31.
go back to reference Figueira FR, Umpierre D, Casali KR, Tetelbom PS, Henn NT, Ribeiro JP et al (2013) Aerobic and combined exercise sessions reduce glucose variability in type 2 diabetes: crossover randomized trial. PLoS ONE 8:e57733CrossRefPubMedPubMedCentral Figueira FR, Umpierre D, Casali KR, Tetelbom PS, Henn NT, Ribeiro JP et al (2013) Aerobic and combined exercise sessions reduce glucose variability in type 2 diabetes: crossover randomized trial. PLoS ONE 8:e57733CrossRefPubMedPubMedCentral
32.
go back to reference Kong Z, Sun S, Liu M, Shi Q (2016) Short-term high-intensity interval training on body composition and blood glucose in overweight and obese young women. J Diabetes Res 2016:4073618CrossRefPubMedPubMedCentral Kong Z, Sun S, Liu M, Shi Q (2016) Short-term high-intensity interval training on body composition and blood glucose in overweight and obese young women. J Diabetes Res 2016:4073618CrossRefPubMedPubMedCentral
33.
go back to reference Peake JM, Tan SJ, Markworth JF, Broadbent JA, Skinner TL, Cameron-Smith D (2014) Metabolic and hormonal responses to isoenergetic high-intensity interval exercise and continuous moderate-intensity exercise. Am J Physiol Endocrinol Metab 307:E539–E552CrossRefPubMed Peake JM, Tan SJ, Markworth JF, Broadbent JA, Skinner TL, Cameron-Smith D (2014) Metabolic and hormonal responses to isoenergetic high-intensity interval exercise and continuous moderate-intensity exercise. Am J Physiol Endocrinol Metab 307:E539–E552CrossRefPubMed
34.
go back to reference Smith-Ryan AE, Melvin MN, Wingfield HL (2015) High-intensity interval training: modulating interval duration in overweight/obese men. Phys Sportsmed 43:107–113CrossRefPubMedPubMedCentral Smith-Ryan AE, Melvin MN, Wingfield HL (2015) High-intensity interval training: modulating interval duration in overweight/obese men. Phys Sportsmed 43:107–113CrossRefPubMedPubMedCentral
35.
go back to reference Jelleyman C, Yates T, Donovan GO, Gray LJ, King JA, Khunti K et al (2015) Physical activity/metabolic effects the effects of high-intensity interval training on glucose regulation and insulin resistance: a meta-analysis. Obes Rev 16:942–961CrossRefPubMed Jelleyman C, Yates T, Donovan GO, Gray LJ, King JA, Khunti K et al (2015) Physical activity/metabolic effects the effects of high-intensity interval training on glucose regulation and insulin resistance: a meta-analysis. Obes Rev 16:942–961CrossRefPubMed
36.
go back to reference van Loon LJC, Koopman R, Stegen JHCH, Wagenmakers AJM, Keizer HA, Saris WHM (2003) Intramyocellular lipids form an important substrate source during moderate intensity exercise in endurance-trained males in a fasted state. J Physiol 553:611–625CrossRefPubMedPubMedCentral van Loon LJC, Koopman R, Stegen JHCH, Wagenmakers AJM, Keizer HA, Saris WHM (2003) Intramyocellular lipids form an important substrate source during moderate intensity exercise in endurance-trained males in a fasted state. J Physiol 553:611–625CrossRefPubMedPubMedCentral
Metadata
Title
Effects of a single session of high-intensity interval exercise and moderate-intensity continuous exercise on biochemical cardiovascular risk factors in obese males
Authors
Ana Paula Trussardi Fayh
Victor Araújo Ferreira Matos
Daniel Costa de Souza
Victor Oliveira Albuquerque dos Santos
Cristiane da Silva Ramos Marinho
Alexandre Coelho Serquiz
Rogerio Friedman
Eduardo Caldas Costa
Publication date
01-08-2018
Publisher
Springer Milan
Published in
Sport Sciences for Health / Issue 2/2018
Print ISSN: 1824-7490
Electronic ISSN: 1825-1234
DOI
https://doi.org/10.1007/s11332-018-0435-4

Other articles of this Issue 2/2018

Sport Sciences for Health 2/2018 Go to the issue