Top

Graefe's Archive for Clinical and Experimental Ophthalmology

Published in:

01-10-2018 | Glaucoma

Effectiveness and safety of sulcus fixation of Baerveldt glaucoma implants in glaucomatous eyes in patients who underwent multiple intraocular surgeries

Authors: Sotaro Mori, Mari Sakamoto, Takuji Kurimoto, Akiyasu Kanamori, Kaori Ueda, Yukako Inoue, Yuko Yamada, Makoto Nakamura

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology | Issue 10/2018

Abstract

Purpose

The purpose of this study was to evaluate the surgical success of sulcus fixation of Baerveldt glaucoma implant (BGIs) in special reference to corneal damage.

Methods

This observational prospective cohort study included 24 patients who underwent a median of 3.0 previous intraocular surgeries and sulcus fixation of BGIs for the first time. The intraocular pressure (IOP), the number of ocular hypotensives used, corneal endothelial cell density (ECD), and logMAR-converted best-corrected visual acuity (VA) of each patient were measured preoperatively and postoperatively until 12 months after surgery. Surgical success was evaluated after 12 months based on the reduction of IOP (5–21 mmHg and > 20% reduction), corneal damage (postoperative development of decompensation, unmeasurable ECD, or ECD reduction of > 20%), loss of light perception, and need for additional surgeries.

Results

Surgical success was noted in 16 (66.7%) patients when corneal damage was included as a failure criterion, whereas surgery was successful in 21 (87.5%) patients when solely judged using IOP control similarly as previous clinical trials. The median IOP decreased from 27.5 mmHg preoperatively to 14.5 mmHg postoperatively (P < 0.0001). The number of ocular hypotensives was significantly reduced postoperatively (P < 0.0001). The median postoperative ECD reduction was only 0.15%, although ECD could not be measured during follow-up or it was significantly reduced by > 20% in six patients. VA was not significantly reduced after surgery. Adverse effects were observed in 15 patients (62.5 cumulative %).

Conclusion

Sulcus fixation of BGIs may be effective and safe in patients with glaucomatous eyes who underwent multiple prior intraocular surgeries.

Gedde SJ, Schiffman JC, Feuer WJ, Herndon LW, Brandt JD, Budenz DL (2012) Treatment outcomes in the Tube Versus Trabeculectomy (TVT) study after five years of follow-up. Am J Ophthalmol 153:789–803.e782. https://doi.org/10.1016/j.ajo.2011.10.026 CrossRefPubMedPubMedCentral

Budenz DL, Barton K, Gedde SJ, Feuer WJ, Schiffman J, Costa VP, Godfrey DG, Buys YM (2015) Five-year treatment outcomes in the Ahmed Baerveldt comparison study. Ophthalmology 122:308–316. https://doi.org/10.1016/j.ophtha.2014.08.043 CrossRefPubMed

Rumelt S, Rehany U (1998) Implantation of glaucoma drainage implant tube into the ciliary sulcus in patients with corneal transplants. Arch Ophthalmol 116:685–687CrossRefPubMed

Tello C, Espana EM, Mora R, Dorairaj S, Liebmann JM, Ritch R (2007) Baerveldt glaucoma implant insertion in the posterior chamber sulcus. Br J Ophthalmol 91:739–742. https://doi.org/10.1136/bjo.2006.107839 CrossRefPubMedPubMedCentral

Prata TS, Mehta A, De Moraes CG, Tello C, Liebmann J, Ritch R (2010) Baerveldt glaucoma implant in the ciliary sulcus: midterm follow-up. J Glaucoma 19:15–18. https://doi.org/10.1097/IJG.0b013e3181a2fc2d CrossRefPubMed

Weiner A, Cohn AD, Balasubramaniam M, Weiner AJ (2010) Glaucoma tube shunt implantation through the ciliary sulcus in pseudophakic eyes with high risk of corneal decompensation. J Glaucoma 19:405–411. https://doi.org/10.1097/IJG.0b013e3181bdb52d CrossRefPubMed

Weiner Y, Faridi O, Weiner A (2013) Clinical experience with sulcus-implanted Baerveldt glaucoma tube shunts fully concealed behind the iris in undilated pseudophakic eyes. J Glaucoma 22:667–671. https://doi.org/10.1097/IJG.0b013e31829c024c CrossRefPubMed

Gedde SJ, Herndon LW, Brandt JD, Budenz DL, Feuer WJ, Schiffman JC (2012) Postoperative complications in the Tube Versus Trabeculectomy (TVT) study during five years of follow-up. Am J Ophthalmol 153:804–814.e801. https://doi.org/10.1016/j.ajo.2011.10.024 CrossRefPubMedPubMedCentral

Budenz DL, Feuer WJ, Barton K, Schiffman J, Costa VP, Godfrey DG, Buys YM (2016) Postoperative complications in the Ahmed Baerveldt comparison study during five years of follow-up. Am J Ophthalmol 163:75–82.e73. https://doi.org/10.1016/j.ajo.2015.11.023 CrossRefPubMed

10.

Heuer DK, Barton K, Grehn F et al (2008) Consensus on definitions of success. In: Shaarawy TM, Sherwood MB, Grehn F (eds) Guidelines on design and reporting of surgical trials. Kugler Publications, Amsterdam, pp 15–24

11.

Topouzis F, Coleman AL, Choplin N, Bethlem MM, Hill R, Yu F, Panek WC, Wilson MR (1999) Follow-up of the original cohort with the Ahmed glaucoma valve implant. Am J Ophthalmol 128:198–204CrossRefPubMed

12.

Tan AN, Webers CA, Berendschot TT, de Brabander J, de Witte PM, Nuijts RM, Schouten JS, Beckers HJ (2017) Corneal endothelial cell loss after Baerveldt glaucoma drainage device implantation in the anterior chamber. Acta Ophthalmol 95:91–96. https://doi.org/10.1111/aos.13161 CrossRefPubMed

13.

Kim CS, Yim JH, Lee EK, Lee NH (2008) Changes in corneal endothelial cell density and morphology after Ahmed glaucoma valve implantation during the first year of follow up. Clin Exp Ophthalmol 36:142–147. https://doi.org/10.1111/j.1442-9071.2008.01683.x CrossRefPubMed

14.

Mendrinos E, Dosso A, Sommerhalder J, Shaarawy T (2009) Coupling of HRT II and AS-OCT to evaluate corneal endothelial cell loss and in vivo visualization of the Ahmed glaucoma valve implant. Eye (London) 23:1836–1844. https://doi.org/10.1038/eye.2008.321 CrossRef

15.

Lee EK, Yun YJ, Lee JE, Yim JH, Kim CS (2009) Changes in corneal endothelial cells after Ahmed glaucoma valve implantation: 2-year follow-up. Am J Ophthalmol 148:361–367. https://doi.org/10.1016/j.ajo.2009.04.016 CrossRefPubMed

16.

Hau S, Scott A, Bunce C, Barton K (2011) Corneal endothelial morphology in eyes implanted with anterior chamber aqueous shunts. Cornea 30:50–55. https://doi.org/10.1097/ICO.0b013e3181e16d7d CrossRefPubMed

17.

Kim KN, Lee SB, Lee YH, Lee JJ, Lim HB, Kim CS (2016) Changes in corneal endothelial cell density and the cumulative risk of corneal decompensation after Ahmed glaucoma valve implantation. Br J Ophthalmol 100:933–938. https://doi.org/10.1136/bjophthalmol-2015-306894 CrossRefPubMed

18.

Lass JH, Benetz BA, Gal RL, Kollman C, Raghinaru D, Dontchev M, Mannis MJ, Holland EJ, Chow C, McCoy K, Price FW Jr, Sugar A, Verdier DD, Beck RW (2013) Donor age and factors related to endothelial cell loss 10 years after penetrating keratoplasty: Specular Microscopy Ancillary Study. Ophthalmology 120:2428–2435. https://doi.org/10.1016/j.ophtha.2013.08.044 CrossRefPubMed

19.

McDermott ML, Swendris RP, Shin DH, Juzych MS, Cowden JW (1993) Corneal endothelial cell counts after Molteno implantation. Am J Ophthalmol 115:93–96CrossRefPubMed

20.

Kim MS, Kim KN, Kim CS (2016) Changes in corneal endothelial cell after Ahmed Glaucoma valve implantation and trabeculectomy: 1-year follow-up. Korean J Ophthalmol 30:416–425. https://doi.org/10.3341/kjo.2016.30.6.416 CrossRefPubMedPubMedCentral

21.

Macdonald JM, Geroski DH, Edelhauser HF (1987) Effect of inflammation on the corneal endothelial pump and barrier. Curr Eye Res 6:1125–1132CrossRefPubMed

Title: Effectiveness and safety of sulcus fixation of Baerveldt glaucoma implants in glaucomatous eyes in patients who underwent multiple intraocular surgeries
Authors: Sotaro Mori
Mari Sakamoto
Takuji Kurimoto
Akiyasu Kanamori
Kaori Ueda
Yukako Inoue
Yuko Yamada
Makoto Nakamura
Publication date: 01-10-2018
Publisher: Springer Berlin Heidelberg
Published in: Graefe's Archive for Clinical and Experimental Ophthalmology / Issue 10/2018
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI: https://doi.org/10.1007/s00417-018-4044-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Effectiveness and safety of sulcus fixation of Baerveldt glaucoma implants in glaucomatous eyes in patients who underwent multiple intraocular surgeries

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

Please log in to get access to this content

Other articles of this Issue 10/2018

Comparative analysis of visual outcomes, reading skills, contrast sensitivity, and patient satisfaction with two models of trifocal diffractive intraocular lenses and an extended range of vision intraocular lens

Quantitative assessment of macular contraction and vitreoretinal interface alterations in diabetic macular edema treated with intravitreal anti-VEGF injections

Flattening of retinal pigment epithelial detachments after pneumatic displacement of submacular hemorrhages secondary to age-related macular degeneration

Application of autologous serum eye drops after pterygium surgery: a prospective study

Prevalences of segmentation errors and motion artifacts in OCT-angiography differ among retinal diseases

Different glaucoma types and glaucoma surgeries among different age groups