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Critical Care
Published in: Critical Care 1/2011

Open Access 01-02-2011 | Poster presentation

Effect of bacterial load versus duration of exposure to bacteria on plasma TNFα concentrations in porcine fecal peritonitis

Authors: T Correa, L Brander, S Djafarzadeh, R Schröder, J Takala, A Reintam Blaser, M Vuda, S Mathias Jakob

Published in: Critical Care | Special Issue 1/2011

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Excerpt

The clinical relevance of preclinical sepsis research has been questioned [1]. This may in part be the result of varying degrees of experimental inflammatory insults. The objective of this study was to quantify inflammation based on plasma TNFα levels after exposure to two different bacterial loads, and after different lengths of bacterial incubation in the peritoneal cavity. …
Literature
1.
Lamontagne F: Systematic review of reviews including animal studies addressing therapeutic interventions for sepsis. Crit Care Med 2010, 38: 2401-2408. 10.1097/CCM.0b013e3181fa0468CrossRefPubMed
Metadata
Title
Effect of bacterial load versus duration of exposure to bacteria on plasma TNFα concentrations in porcine fecal peritonitis
Authors
T Correa
L Brander
S Djafarzadeh
R Schröder
J Takala
A Reintam Blaser
M Vuda
S Mathias Jakob
Publication date
01-02-2011
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 1/2011
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc9668

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