Skip to main content
Top
Published in: Journal of the International Society of Sports Nutrition 1/2014

Open Access 01-12-2014 | Research article

Effect of an herbal/botanical supplement on strength, balance, and muscle function following 12-weeks of resistance training: a placebo controlled study

Authors: Jonathan Furlong, Corey A Rynders, Mark Sutherlin, James Patrie, Frank I Katch, Jay Hertel, Arthur Weltman

Published in: Journal of the International Society of Sports Nutrition | Issue 1/2014

Login to get access

Abstract

Background

StemSport (SS; StemTech International, Inc. San Clemente, CA) contains a proprietary blend of the botanical Aphanizomenon flos-aquae and several herbal antioxidant and anti-inflammatory substances. SS has been purported to accelerate tissue repair and restore muscle function following resistance exercise. Here, we examine the effects of SS supplementation on strength adaptations resulting from a 12-week resistance training program in healthy young adults.

Methods

Twenty-four young adults (16 males, 8 females, mean age = 20.5 ± 1.9 years, mass = 70.9 ± 11.9 kg, stature = 176.6 ± 9.9 cm) completed the twelve week training program. The study design was a double-blind, placebo controlled parallel group trial. Subjects either received placebo or StemSport supplement (SS; mg/day) during the training. 1-RM bench press, 1-RM leg press, vertical jump height, balance (star excursion and center of mass excursion), isokinetic strength (elbow and knee flexion/extension) and perception of recovery were measured at baseline and following the 12-week training intervention.

Results

Resistance training increased 1-RM strength (p < 0.008), vertical jump height (p < 0.03), and isokinetic strength (p < 0.05) in both SS and placebo groups. No significant group-by-time interactions were observed (all p-values >0.10).

Conclusions

These data suggest that compared to placebo, the SS herbal/botanical supplement did not enhance training induced adaptations to strength, balance, and muscle function above strength training alone.
Appendix
Available only for authorised users
Literature
1.
go back to reference Roy BD, Tarnopolsky MA: Influence of differing macronutrient intakes on muscle glycogen resynthesis after resistance exercise. J Appl Physiol. 1998, 84: 890-6.PubMed Roy BD, Tarnopolsky MA: Influence of differing macronutrient intakes on muscle glycogen resynthesis after resistance exercise. J Appl Physiol. 1998, 84: 890-6.PubMed
2.
go back to reference Conley MS, Stone MH: Carbohydrate ingestion/supplementation or resistance exercise and training. Sports Med. 1996, 21: 7-17. 10.2165/00007256-199621010-00002.CrossRefPubMed Conley MS, Stone MH: Carbohydrate ingestion/supplementation or resistance exercise and training. Sports Med. 1996, 21: 7-17. 10.2165/00007256-199621010-00002.CrossRefPubMed
3.
go back to reference Biolo G, Tipton KD, Klein S, Wolfe RR: An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein. Am J Physiol. 1997, 273: E122-9.PubMed Biolo G, Tipton KD, Klein S, Wolfe RR: An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein. Am J Physiol. 1997, 273: E122-9.PubMed
4.
go back to reference Tipton KD, Ferrando AA, Phillips SM, Doyle D, Wolfe RR: Postexercise net protein synthesis in human muscle from orally administered amino acids. Am J Physiol. 1999, 276: E628-34.PubMed Tipton KD, Ferrando AA, Phillips SM, Doyle D, Wolfe RR: Postexercise net protein synthesis in human muscle from orally administered amino acids. Am J Physiol. 1999, 276: E628-34.PubMed
5.
go back to reference Nissen SL, Sharp RL: Effect of dietary supplements on lean mass and strength gains with resistance exercise: a meta-analysis. J Appl Physiol. 2003, 94: 651-9.CrossRefPubMed Nissen SL, Sharp RL: Effect of dietary supplements on lean mass and strength gains with resistance exercise: a meta-analysis. J Appl Physiol. 2003, 94: 651-9.CrossRefPubMed
6.
go back to reference Baechle TRE, Roger W: Essentials of Strength Training and Conditioning. 2001, Champaign, IL: Human Kinetics Baechle TRE, Roger W: Essentials of Strength Training and Conditioning. 2001, Champaign, IL: Human Kinetics
7.
go back to reference Gribble PA, Hertel J, Plisky P: Using the star excursion balance test to assess dynamic postural-control deficits and outcomes in lower extremity injury: a literature and systematic review. J Athl Train. 2012, 47: 339-57.PubMedCentralPubMed Gribble PA, Hertel J, Plisky P: Using the star excursion balance test to assess dynamic postural-control deficits and outcomes in lower extremity injury: a literature and systematic review. J Athl Train. 2012, 47: 339-57.PubMedCentralPubMed
9.
go back to reference Jensen GS, Hart AN, Zaske LA, Drapeau C, Gupta N, Schaeffer DJ, Cruickshank JA: Mobilization of human CD34+ CD133+ and CD34+ CD133(−) stem cells in vivo by consumption of an extract from Aphanizomenon flos-aquae–related to modulation of CXCR4 expression by an L-selectin ligand?. Cardiovasc Revasc Med. 2007, 8: 189-202. 10.1016/j.carrev.2007.03.004.CrossRefPubMed Jensen GS, Hart AN, Zaske LA, Drapeau C, Gupta N, Schaeffer DJ, Cruickshank JA: Mobilization of human CD34+ CD133+ and CD34+ CD133(−) stem cells in vivo by consumption of an extract from Aphanizomenon flos-aquae–related to modulation of CXCR4 expression by an L-selectin ligand?. Cardiovasc Revasc Med. 2007, 8: 189-202. 10.1016/j.carrev.2007.03.004.CrossRefPubMed
10.
go back to reference Shytle DR, Tan J, Ehrhart J, Smith AJ, Sanberg CD, Sanberg PR, Anderson J, Bickford PC: Effects of blue-green algae extracts on the proliferation of human adult stem cells in vitro: a preliminary study. Med Sci Monit. 2010, 16: BR1-5.PubMed Shytle DR, Tan J, Ehrhart J, Smith AJ, Sanberg CD, Sanberg PR, Anderson J, Bickford PC: Effects of blue-green algae extracts on the proliferation of human adult stem cells in vitro: a preliminary study. Med Sci Monit. 2010, 16: BR1-5.PubMed
11.
go back to reference Weecharangsan W, Opanasopit P, Sukma M, Ngawhirunpat T, Sotanaphun U, Siripong P: Antioxidative and neuroprotective activities of extracts from the fruit hull of mangosteen (Garcinia mangostana Linn.). Med Princ Pract. 2006, 15: 281-7. 10.1159/000092991.CrossRefPubMed Weecharangsan W, Opanasopit P, Sukma M, Ngawhirunpat T, Sotanaphun U, Siripong P: Antioxidative and neuroprotective activities of extracts from the fruit hull of mangosteen (Garcinia mangostana Linn.). Med Princ Pract. 2006, 15: 281-7. 10.1159/000092991.CrossRefPubMed
12.
go back to reference Pilarski R, Zielinski H, Ciesiolka D, Gulewicz K: Antioxidant activity of ethanolic and aqueous extracts of Uncaria tomentosa (Willd.) DC. J Ethnopharmacol. 2006, 104: 18-23. 10.1016/j.jep.2005.08.046.CrossRefPubMed Pilarski R, Zielinski H, Ciesiolka D, Gulewicz K: Antioxidant activity of ethanolic and aqueous extracts of Uncaria tomentosa (Willd.) DC. J Ethnopharmacol. 2006, 104: 18-23. 10.1016/j.jep.2005.08.046.CrossRefPubMed
13.
go back to reference Purdy Lloyd KL, Wasmund W, Smith L, Raven PB: Clinical Effects of a Dietary Antioxidant Silicate Supplement, Microhydrin((R)), on Cardiovascular Responses to Exercise. J Med Food. 2001, 4: 151-9. 10.1089/109662001753165738.CrossRefPubMed Purdy Lloyd KL, Wasmund W, Smith L, Raven PB: Clinical Effects of a Dietary Antioxidant Silicate Supplement, Microhydrin((R)), on Cardiovascular Responses to Exercise. J Med Food. 2001, 4: 151-9. 10.1089/109662001753165738.CrossRefPubMed
14.
go back to reference Goud VK, Polasa K, Krishnaswamy K: Effect of turmeric on xenobiotic metabolising enzymes. Plant Foods Hum Nutr. 1993, 44: 87-92. 10.1007/BF01088486.CrossRefPubMed Goud VK, Polasa K, Krishnaswamy K: Effect of turmeric on xenobiotic metabolising enzymes. Plant Foods Hum Nutr. 1993, 44: 87-92. 10.1007/BF01088486.CrossRefPubMed
15.
go back to reference Sumi H, Hamada H, Nakanishi K, Hiratani H: Enhancement of the fibrinolytic activity in plasma by oral administration of nattokinase. Acta Haematol. 1990, 84: 139-43. 10.1159/000205051.CrossRefPubMed Sumi H, Hamada H, Nakanishi K, Hiratani H: Enhancement of the fibrinolytic activity in plasma by oral administration of nattokinase. Acta Haematol. 1990, 84: 139-43. 10.1159/000205051.CrossRefPubMed
16.
go back to reference Kubo M, Asano T, Shiomoto H, Matsuda H: Studies on rehmanniae radix. I. Effect of 50% ethanolic extract from steamed and dried rehmanniae radix on hemorheology in arthritic and thrombosic rats. Biol Pharm Bull. 1994, 17: 1282-6. 10.1248/bpb.17.1282.CrossRefPubMed Kubo M, Asano T, Shiomoto H, Matsuda H: Studies on rehmanniae radix. I. Effect of 50% ethanolic extract from steamed and dried rehmanniae radix on hemorheology in arthritic and thrombosic rats. Biol Pharm Bull. 1994, 17: 1282-6. 10.1248/bpb.17.1282.CrossRefPubMed
17.
go back to reference Bloomer RJ, Falvo MJ, Schilling BK, Smith WA: Prior exercise and antioxidant supplementation: effect on oxidative stress and muscle injury. J Int Soc Sports Nutr. 2007, 4: 9-10.1186/1550-2783-4-9.PubMedCentralCrossRefPubMed Bloomer RJ, Falvo MJ, Schilling BK, Smith WA: Prior exercise and antioxidant supplementation: effect on oxidative stress and muscle injury. J Int Soc Sports Nutr. 2007, 4: 9-10.1186/1550-2783-4-9.PubMedCentralCrossRefPubMed
18.
go back to reference Bobeuf F, Labonte M, Dionne IJ, Khalil A: Combined effect of antioxidant supplementation and resistance training on oxidative stress markers, muscle and body composition in an elderly population. J Nutr Health Aging. 2011, 15: 883-9. 10.1007/s12603-011-0097-2.CrossRefPubMed Bobeuf F, Labonte M, Dionne IJ, Khalil A: Combined effect of antioxidant supplementation and resistance training on oxidative stress markers, muscle and body composition in an elderly population. J Nutr Health Aging. 2011, 15: 883-9. 10.1007/s12603-011-0097-2.CrossRefPubMed
19.
go back to reference Ristow M, Zarse K, Oberbach A, Kloting N, Birringer M, Kiehntopf M, Stumvoll M, Kahn CR, Bluher M: Antioxidants prevent health-promoting effects of physical exercise in humans. Proc Natl Acad Sci U S A. 2009, 106: 8665-70. 10.1073/pnas.0903485106.PubMedCentralCrossRefPubMed Ristow M, Zarse K, Oberbach A, Kloting N, Birringer M, Kiehntopf M, Stumvoll M, Kahn CR, Bluher M: Antioxidants prevent health-promoting effects of physical exercise in humans. Proc Natl Acad Sci U S A. 2009, 106: 8665-70. 10.1073/pnas.0903485106.PubMedCentralCrossRefPubMed
20.
go back to reference Krentz JR, Quest B, Farthing JP, Quest DW, Chilibeck PD: The effects of ibuprofen on muscle hypertrophy, strength, and soreness during resistance training. Appl Physiol Nutr Metab. 2008, 33: 470-5. 10.1139/H08-019.CrossRefPubMed Krentz JR, Quest B, Farthing JP, Quest DW, Chilibeck PD: The effects of ibuprofen on muscle hypertrophy, strength, and soreness during resistance training. Appl Physiol Nutr Metab. 2008, 33: 470-5. 10.1139/H08-019.CrossRefPubMed
21.
go back to reference Novak ML, Billich W, Smith SM, Sukhija KB, McLoughlin TJ, Hornberger TA, Koh TJ: COX-2 inhibitor reduces skeletal muscle hypertrophy in mice. Am J Physiol Regul Integr Comp Physiol. 2009, 296: R1132-9. 10.1152/ajpregu.90874.2008.PubMedCentralCrossRefPubMed Novak ML, Billich W, Smith SM, Sukhija KB, McLoughlin TJ, Hornberger TA, Koh TJ: COX-2 inhibitor reduces skeletal muscle hypertrophy in mice. Am J Physiol Regul Integr Comp Physiol. 2009, 296: R1132-9. 10.1152/ajpregu.90874.2008.PubMedCentralCrossRefPubMed
22.
go back to reference Flann KL, LaStayo PC, McClain DA, Hazel M, Lindstedt SL: Muscle damage and muscle remodeling: no pain, no gain?. J Exp Biol. 2011, 214: 674-9. 10.1242/jeb.050112.CrossRefPubMed Flann KL, LaStayo PC, McClain DA, Hazel M, Lindstedt SL: Muscle damage and muscle remodeling: no pain, no gain?. J Exp Biol. 2011, 214: 674-9. 10.1242/jeb.050112.CrossRefPubMed
23.
go back to reference Dannelly BD, Otey SC, Croy T, Harrison B, Rynders CA, Hertel JN, Weltman A: The effectiveness of traditional and sling exercise strength training in women. J Strength Cond Res. 2011, 25: 464-71. 10.1519/JSC.0b013e318202e473.CrossRefPubMed Dannelly BD, Otey SC, Croy T, Harrison B, Rynders CA, Hertel JN, Weltman A: The effectiveness of traditional and sling exercise strength training in women. J Strength Cond Res. 2011, 25: 464-71. 10.1519/JSC.0b013e318202e473.CrossRefPubMed
24.
go back to reference Willoughby DS, Stout JR, Wilborn CD: Effects of resistance training and protein plus amino acid supplementation on muscle anabolism, mass, and strength. Amino Acids. 2007, 32: 467-77. 10.1007/s00726-006-0398-7.CrossRefPubMed Willoughby DS, Stout JR, Wilborn CD: Effects of resistance training and protein plus amino acid supplementation on muscle anabolism, mass, and strength. Amino Acids. 2007, 32: 467-77. 10.1007/s00726-006-0398-7.CrossRefPubMed
Metadata
Title
Effect of an herbal/botanical supplement on strength, balance, and muscle function following 12-weeks of resistance training: a placebo controlled study
Authors
Jonathan Furlong
Corey A Rynders
Mark Sutherlin
James Patrie
Frank I Katch
Jay Hertel
Arthur Weltman
Publication date
01-12-2014
Publisher
BioMed Central
DOI
https://doi.org/10.1186/1550-2783-11-23

Other articles of this Issue 1/2014

Journal of the International Society of Sports Nutrition 1/2014 Go to the issue