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International Urogynecology Journal
Published in: International Urogynecology Journal 2/2009

01-02-2009 | Original Article

Effect of alfuzosin on female primary bladder neck obstruction

Authors: A. Athanasopoulos, K. Gyftopoulos, K. Giannitsas, P. Perimenis

Published in: International Urogynecology Journal | Issue 2/2009

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Abstract

Our objective was to assess the effect of the selective α1-blocker alfuzosin on urodynamic parameters and quality of life in female patients with primary bladder neck obstruction (PBNO). Twenty-five women identified as having PBNO were included in the study. After the initial assessment of urodynamic parameters and bother score index, all patients were treated with alfuzosin 5 mg twice daily for 8 weeks. After this period of time, the patients were reassessed with the same methodology as pretreatment. Symptoms subjectively improved, and patients’ satisfaction significantly increased in 64% of the patients (16 out of 25). Most urodynamic parameters were also significantly improved after treatment with alfuzosin. Alfuzosin significantly improved urodynamic parameters and alleviated bother score in almost two thirds of patients with PBNO and can be an effective first-line treatment of this situation.
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Metadata
Title
Effect of alfuzosin on female primary bladder neck obstruction
Authors
A. Athanasopoulos
K. Gyftopoulos
K. Giannitsas
P. Perimenis
Publication date
01-02-2009
Publisher
Springer-Verlag
Published in
International Urogynecology Journal / Issue 2/2009
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-008-0749-x

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