Skip to main content
Top
Published in: Systematic Reviews 1/2014

Open Access 01-12-2014 | Protocol

Educational interventions for general practitioners to identify and manage depression as a suicide risk factor in young people: a systematic review and meta-analysis protocol

Authors: Lynda Tait, Maria Michail

Published in: Systematic Reviews | Issue 1/2014

Login to get access

Abstract

Background

Suicide is a major public health problem and globally is the second leading cause of death in young adults. Globally, there are 164,000 suicides per year in young people under 25 years. Depression is a strong risk factor for suicide. Evidence shows that 45% of those completing suicide, including young adults, contact their general practitioner rather than a mental health professional in the month before their death. Further evidence indicates that risk factors or early warning signs of suicide in young people go undetected and untreated by general practitioners. Healthcare-based suicide prevention interventions targeted at general practitioners are designed to increase identification of at-risk young people. The rationale of this type of intervention is that early identification and improved clinical management of at-risk individuals will reduce morbidity and mortality. This systematic review will synthesise evidence on the effectiveness of education interventions for general practitioners in identifying and managing depression as a suicide risk factor in young people.

Methods/design

We shall conduct a systematic review and meta-analysis following the Cochrane Handbook for Systematic Reviews of Interventions guidelines and conform to the reporting guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations. Electronic databases will be systematically searched for randomised controlled trials and quasi-experimental studies investigating the effectiveness of interventions for general practitioners in identifying and managing depression as a suicide risk factor in young people in comparison to any other intervention, no intervention, usual care or waiting list. Grey literature will be searched by screening trial registers. Only studies published in English will be included. No date restrictions will be applied. Two authors will independently screen titles and abstracts of potential studies. The primary outcome is identification and management of depression. Secondary outcomes are suicidal ideation, suicide attempts, deliberate self-harm, knowledge of suicide risk factors and suicide-related behaviours, attitudes towards suicide risk and suicide-related behaviours, confidence in dealing with suicide risk factors and suicide-related behaviour.

Discussion

Our study will inform the development of future education interventions and provide feasibility and acceptability evidence, to help general practitioners identify and manage suicidal behaviour in young people.

Systematic review registration

PROSPERO registration number: CRD42014009110.
Appendix
Available only for authorised users
Literature
1.
go back to reference World Health Organization: Preventing Suicide: A Global Imperative. 2014, Geneva: World Health Organization World Health Organization: Preventing Suicide: A Global Imperative. 2014, Geneva: World Health Organization
2.
go back to reference World Health Organization: Preventing Suicide. A Resource for Primary Care Health Workers. 2000, Geneva: World Health Organization World Health Organization: Preventing Suicide. A Resource for Primary Care Health Workers. 2000, Geneva: World Health Organization
3.
go back to reference Patton GC, Coffey C, Sawyer SM, Viner RM, Haller DM, Bose K, Vos T, Ferguson J, Mathers CD: Global patterns of mortality in young people: a systematic analysis of population health data. Lancet. 2009, 374: 881-892. 10.1016/S0140-6736(09)60741-8.CrossRefPubMed Patton GC, Coffey C, Sawyer SM, Viner RM, Haller DM, Bose K, Vos T, Ferguson J, Mathers CD: Global patterns of mortality in young people: a systematic analysis of population health data. Lancet. 2009, 374: 881-892. 10.1016/S0140-6736(09)60741-8.CrossRefPubMed
4.
go back to reference Beautrais AL: Suicides and serious suicide attempts: two populations or one?. Psychol Med. 2001, 31: 837-845.CrossRefPubMed Beautrais AL: Suicides and serious suicide attempts: two populations or one?. Psychol Med. 2001, 31: 837-845.CrossRefPubMed
5.
go back to reference Gould MS, Greenberg T, Velting DM, Shaffer D: Youth suicide risk and preventive interventions: a review of the past 10 years. J Am Acad Child Adolesc Psychiatry. 2003, 42: 386-405. 10.1097/01.CHI.0000046821.95464.CF.CrossRefPubMed Gould MS, Greenberg T, Velting DM, Shaffer D: Youth suicide risk and preventive interventions: a review of the past 10 years. J Am Acad Child Adolesc Psychiatry. 2003, 42: 386-405. 10.1097/01.CHI.0000046821.95464.CF.CrossRefPubMed
6.
go back to reference Dumais A, Lesage AD, Lalovic A, Séguin M, Tousignant M, Chawky N, Turecki G: Is violent method of suicide a behavioral marker of lifetime aggression?. Am J Psychiatry. 2005, 162: 1375-1378. 10.1176/appi.ajp.162.7.1375.CrossRefPubMed Dumais A, Lesage AD, Lalovic A, Séguin M, Tousignant M, Chawky N, Turecki G: Is violent method of suicide a behavioral marker of lifetime aggression?. Am J Psychiatry. 2005, 162: 1375-1378. 10.1176/appi.ajp.162.7.1375.CrossRefPubMed
7.
go back to reference Nock MK, Kessler RC: Prevalence of and risk factors for suicide attempts versus suicide gestures: analysis of the National Comorbidity Survey. J Abnorm Psychol. 2006, 115: 616-623.CrossRefPubMed Nock MK, Kessler RC: Prevalence of and risk factors for suicide attempts versus suicide gestures: analysis of the National Comorbidity Survey. J Abnorm Psychol. 2006, 115: 616-623.CrossRefPubMed
8.
go back to reference Shaffer D, Gould MS, Fisher P, Trautman P, Moreau D, Kleinman M, Flory M: Psychiatric diagnosis in child and adolescent suicide. Arch Gen Psychiatry. 1996, 53: 339-348. 10.1001/archpsyc.1996.01830040075012.CrossRefPubMed Shaffer D, Gould MS, Fisher P, Trautman P, Moreau D, Kleinman M, Flory M: Psychiatric diagnosis in child and adolescent suicide. Arch Gen Psychiatry. 1996, 53: 339-348. 10.1001/archpsyc.1996.01830040075012.CrossRefPubMed
9.
go back to reference Beautrais AL: Risk factors for suicide and attempted suicide among young people. Aust N Z J Psychiatry. 2000, 34: 420-436. 10.1080/j.1440-1614.2000.00691.x.CrossRefPubMed Beautrais AL: Risk factors for suicide and attempted suicide among young people. Aust N Z J Psychiatry. 2000, 34: 420-436. 10.1080/j.1440-1614.2000.00691.x.CrossRefPubMed
10.
go back to reference Nock MK, Borges G, Bromet EJ, Alonso J, Angermeyer M, Beautrais A, Bruffaerts R, Chiu WT, de Girolamo G, Gluzman S, de Graaf R, Gureje O, Haro JM, Huang Y, Karam E, Kessler RC, Lepine JP, Levinson D, Medina-Mora ME, Ono Y, Posada-Villa J, Williams D: Cross-national prevalence and risk factors for suicidal ideation, plans, and attempts. Br J Psychiatry. 2008, 192: 98-105. 10.1192/bjp.bp.107.040113.CrossRefPubMedPubMedCentral Nock MK, Borges G, Bromet EJ, Alonso J, Angermeyer M, Beautrais A, Bruffaerts R, Chiu WT, de Girolamo G, Gluzman S, de Graaf R, Gureje O, Haro JM, Huang Y, Karam E, Kessler RC, Lepine JP, Levinson D, Medina-Mora ME, Ono Y, Posada-Villa J, Williams D: Cross-national prevalence and risk factors for suicidal ideation, plans, and attempts. Br J Psychiatry. 2008, 192: 98-105. 10.1192/bjp.bp.107.040113.CrossRefPubMedPubMedCentral
11.
12.
go back to reference Welch SS: A review of the literature on the epidemiology of parasuicide in the general population. Psychiatr Serv. 2001, 52: 368-375. 10.1176/appi.ps.52.3.368.CrossRefPubMed Welch SS: A review of the literature on the epidemiology of parasuicide in the general population. Psychiatr Serv. 2001, 52: 368-375. 10.1176/appi.ps.52.3.368.CrossRefPubMed
13.
go back to reference Department of Health: Preventing suicide in England: a cross-government outcomes strategy to save lives. 2012, London: Department of Health Department of Health: Preventing suicide in England: a cross-government outcomes strategy to save lives. 2012, London: Department of Health
14.
go back to reference Silverman MM, Maris R: Suicide Prevention: Toward the Year 2000. 1995, New York: Guilford Publications Silverman MM, Maris R: Suicide Prevention: Toward the Year 2000. 1995, New York: Guilford Publications
15.
go back to reference World Health Organization: Public Health Action for the Prevention of Suicide: A Framework. 2012, Geneva: World Health Organization World Health Organization: Public Health Action for the Prevention of Suicide: A Framework. 2012, Geneva: World Health Organization
16.
go back to reference Goldberg P, Huxley P: Common Mental Disorders: A bio-Social Model. 1992, London: Routledge Goldberg P, Huxley P: Common Mental Disorders: A bio-Social Model. 1992, London: Routledge
17.
go back to reference Luoma JB, Martin CE, Pearson JL: Contact with mental health and primary care providers before suicide: a review of the evidence. Am J Psychiatry. 2002, 159: 909-916. 10.1176/appi.ajp.159.6.909.CrossRefPubMed Luoma JB, Martin CE, Pearson JL: Contact with mental health and primary care providers before suicide: a review of the evidence. Am J Psychiatry. 2002, 159: 909-916. 10.1176/appi.ajp.159.6.909.CrossRefPubMed
18.
go back to reference Taliaferro LA, Oberstar JV, Borowsky IW: Prevention of youth suicide: the role of the primary care physician. J Clin Outcomes Manag. 2012, 19: 270-285. Taliaferro LA, Oberstar JV, Borowsky IW: Prevention of youth suicide: the role of the primary care physician. J Clin Outcomes Manag. 2012, 19: 270-285.
19.
go back to reference Hider P: Youth suicide prevention by primary healthcare professionals: a critical appraisal of the literature. New Zealand Health Technology Assessment (NZHTA). 1998, 1: 1-113. Hider P: Youth suicide prevention by primary healthcare professionals: a critical appraisal of the literature. New Zealand Health Technology Assessment (NZHTA). 1998, 1: 1-113.
20.
go back to reference Gunnell DJ: The Potential for Preventing Suicide. A Review of the Literature on the Effectiveness of Interventions Aimed at Preventing Suicide. 1994, University of Bristol: Bristol Health Care Unit Gunnell DJ: The Potential for Preventing Suicide. A Review of the Literature on the Effectiveness of Interventions Aimed at Preventing Suicide. 1994, University of Bristol: Bristol Health Care Unit
21.
go back to reference Saini P, Windfuhr K, Pearson A, Da Cruz D, Miles C, Cordingley L, While D, Swinson N, Williams A, Shaw J, Appleby L, Kapur N: Suicide prevention in primary care: general practitioners’ views on service availability. BMC Res Notes. 2010, 3: 246-252. 10.1186/1756-0500-3-246.CrossRefPubMedPubMedCentral Saini P, Windfuhr K, Pearson A, Da Cruz D, Miles C, Cordingley L, While D, Swinson N, Williams A, Shaw J, Appleby L, Kapur N: Suicide prevention in primary care: general practitioners’ views on service availability. BMC Res Notes. 2010, 3: 246-252. 10.1186/1756-0500-3-246.CrossRefPubMedPubMedCentral
22.
go back to reference Gilbody S, Whitty P, Grimshaw J, Thomas R: Educational and organizational interventions to improve the management of depression in primary care: a systematic review. JAMA. 2003, 289: 3145-3151. 10.1001/jama.289.23.3145.CrossRefPubMed Gilbody S, Whitty P, Grimshaw J, Thomas R: Educational and organizational interventions to improve the management of depression in primary care: a systematic review. JAMA. 2003, 289: 3145-3151. 10.1001/jama.289.23.3145.CrossRefPubMed
23.
go back to reference Mann JJ, Apter A, Bertolote J, Beautrais A, Currier D, Haas A, Hegerl U, Lonngvist J, Malone K, Marusic A, Mehlum L, Patton G, Phillips M, Rutz W, Rihmer Z, Schmidtke A, Shaffer D, Silverman M, Takahashi Y, Varnik A, Wasserman D, Yip P, Hendin H: Suicide prevention strategies: a systematic review. JAMA. 2005, 294: 2064-2074. 10.1001/jama.294.16.2064.CrossRefPubMed Mann JJ, Apter A, Bertolote J, Beautrais A, Currier D, Haas A, Hegerl U, Lonngvist J, Malone K, Marusic A, Mehlum L, Patton G, Phillips M, Rutz W, Rihmer Z, Schmidtke A, Shaffer D, Silverman M, Takahashi Y, Varnik A, Wasserman D, Yip P, Hendin H: Suicide prevention strategies: a systematic review. JAMA. 2005, 294: 2064-2074. 10.1001/jama.294.16.2064.CrossRefPubMed
24.
go back to reference Tait L, Lester H, Birchwood M, Freemantle N, Wilson S: Design of the BiRmingham Early Detection In untreated psychosis Trial (REDIRECT): cluster randomised controlled trial of general practitioner education in detection of first episode psychosis [ISRCTN87898421]. BMC Health Serv Res. 2005, 5: 19-10.1186/1472-6963-5-19.CrossRefPubMedPubMedCentral Tait L, Lester H, Birchwood M, Freemantle N, Wilson S: Design of the BiRmingham Early Detection In untreated psychosis Trial (REDIRECT): cluster randomised controlled trial of general practitioner education in detection of first episode psychosis [ISRCTN87898421]. BMC Health Serv Res. 2005, 5: 19-10.1186/1472-6963-5-19.CrossRefPubMedPubMedCentral
25.
go back to reference Lester H, Birchwood M, Freemantle N, Michail M, Tait L: REDIRECT: cluster randomised controlled trial of GP training in first-episode psychosis. Br J Gen Pract. 2009, 59: 403-408. Lester H, Birchwood M, Freemantle N, Michail M, Tait L: REDIRECT: cluster randomised controlled trial of GP training in first-episode psychosis. Br J Gen Pract. 2009, 59: 403-408.
26.
go back to reference Pfaff JJ, Acres JG, McKelvey RS: Training general practitioners to recognise and respond to psychological distress and suicidal ideation in young people. Med J Aust. 2001, 174: 222-226.PubMed Pfaff JJ, Acres JG, McKelvey RS: Training general practitioners to recognise and respond to psychological distress and suicidal ideation in young people. Med J Aust. 2001, 174: 222-226.PubMed
28.
go back to reference Appleby L, Morriss R, Gask L, Roland M, Lewis B, Perry A, Battersby L, Colbert N, Green G, Amos T, Davies L, Faragher B: An educational intervention for front-line health professionals in the assessment and management of suicidal patients (The STORM project). Psych Med. 2000, 30: 805-812. 10.1017/S0033291799002494.CrossRef Appleby L, Morriss R, Gask L, Roland M, Lewis B, Perry A, Battersby L, Colbert N, Green G, Amos T, Davies L, Faragher B: An educational intervention for front-line health professionals in the assessment and management of suicidal patients (The STORM project). Psych Med. 2000, 30: 805-812. 10.1017/S0033291799002494.CrossRef
30.
go back to reference Moher D, Liberati A, Tetzlaff J, Altman DG: Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009, 339: b2535-10.1136/bmj.b2535. doi:10.1136/bmj.b2535CrossRefPubMedPubMedCentral Moher D, Liberati A, Tetzlaff J, Altman DG: Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ. 2009, 339: b2535-10.1136/bmj.b2535. doi:10.1136/bmj.b2535CrossRefPubMedPubMedCentral
33.
go back to reference Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J: An inventory for measuring depression. Arch Gen Psychiatry. 1961, 4: 561-571. 10.1001/archpsyc.1961.01710120031004.CrossRefPubMed Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J: An inventory for measuring depression. Arch Gen Psychiatry. 1961, 4: 561-571. 10.1001/archpsyc.1961.01710120031004.CrossRefPubMed
34.
go back to reference World Health Organization: The ICD-10 Classification of Mental and Behavioural Disorders: Clinical Description and Diagnostic Guidelines. 1992, Geneva: World Health Organization World Health Organization: The ICD-10 Classification of Mental and Behavioural Disorders: Clinical Description and Diagnostic Guidelines. 1992, Geneva: World Health Organization
35.
go back to reference American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders. 2013, Washington: American Psychiatric Association, 5 American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders. 2013, Washington: American Psychiatric Association, 5
36.
go back to reference Beck AT, Schuyler D, Herman I: Development of suicidal intent scales. The Prediction of Suicide. Edited by: Beck AT, Resnik HLP, Lettieri DJ. 1974, Bowie, MD: Charles Press, 45-56. Beck AT, Schuyler D, Herman I: Development of suicidal intent scales. The Prediction of Suicide. Edited by: Beck AT, Resnik HLP, Lettieri DJ. 1974, Bowie, MD: Charles Press, 45-56.
37.
go back to reference Joiner TE, Rudd MD, Rajab MH: The Modified Scale for Suicidal Ideation: factors of suicidality and their relation to clinical and diagnostic variables. J Abnorm Psychol. 1997, 106: 260-265.CrossRefPubMed Joiner TE, Rudd MD, Rajab MH: The Modified Scale for Suicidal Ideation: factors of suicidality and their relation to clinical and diagnostic variables. J Abnorm Psychol. 1997, 106: 260-265.CrossRefPubMed
38.
go back to reference Linehan MM, Comtois KA, Brown MZ, Heard HL, Wagner A: Suicide Attempt Self-Injury Interview (SASII): development, reliability, and validity of a scale to assess suicide attempts and intentional self-injury. Psychol Assess. 2006, 18: 303-312.CrossRefPubMed Linehan MM, Comtois KA, Brown MZ, Heard HL, Wagner A: Suicide Attempt Self-Injury Interview (SASII): development, reliability, and validity of a scale to assess suicide attempts and intentional self-injury. Psychol Assess. 2006, 18: 303-312.CrossRefPubMed
39.
go back to reference Kreitman N: Parasuicide. 1977, London, England: John Wiley & Sons Kreitman N: Parasuicide. 1977, London, England: John Wiley & Sons
40.
go back to reference Babiker G, Arnold L: The Language of Injury: Comprehending self-mutilation. 1997, Leicester: BPS books Babiker G, Arnold L: The Language of Injury: Comprehending self-mutilation. 1997, Leicester: BPS books
41.
go back to reference Morgan HG: Death Wishes. The Understanding and Management of Deliberate Self-Harm. 1979, Chichester: Wiley Morgan HG: Death Wishes. The Understanding and Management of Deliberate Self-Harm. 1979, Chichester: Wiley
42.
go back to reference Gratz KL: Measurement of deliberate self-harm: preliminary data on the deliberate self-harm inventory. J Psychopathol Behav Assess. 2001, 23: 253-263. 10.1023/A:1012779403943.CrossRef Gratz KL: Measurement of deliberate self-harm: preliminary data on the deliberate self-harm inventory. J Psychopathol Behav Assess. 2001, 23: 253-263. 10.1023/A:1012779403943.CrossRef
43.
go back to reference Klonsky DE, Glenn KR: Assessing the functions of non-suicidal self-injury: psychometric properties of the Inventory of Statements About Self-injury (ISAS). J Psychopathol Behav Assess. 2009, 31: 215-219. 10.1007/s10862-008-9107-z.CrossRef Klonsky DE, Glenn KR: Assessing the functions of non-suicidal self-injury: psychometric properties of the Inventory of Statements About Self-injury (ISAS). J Psychopathol Behav Assess. 2009, 31: 215-219. 10.1007/s10862-008-9107-z.CrossRef
44.
go back to reference Holmes CB, Howard ME: Recognition of suicide lethality factors by physicians, mental health professionals, ministers, and college students. J Consult Clin Psychol. 1980, 48 (3): 383-387.CrossRefPubMed Holmes CB, Howard ME: Recognition of suicide lethality factors by physicians, mental health professionals, ministers, and college students. J Consult Clin Psychol. 1980, 48 (3): 383-387.CrossRefPubMed
45.
go back to reference Salander Renberg E, Jacobson L: Development of a questionnaire on attitudes towards suicide (ATTS) and its application in a Swedish population. Life Threat Behav. 2003, 33: 52-64. 10.1521/suli.33.1.52.22784.CrossRef Salander Renberg E, Jacobson L: Development of a questionnaire on attitudes towards suicide (ATTS) and its application in a Swedish population. Life Threat Behav. 2003, 33: 52-64. 10.1521/suli.33.1.52.22784.CrossRef
46.
go back to reference Grimholt TK, Haavet OR, Jacobsen D, Sandvik L, Ekeberg L: Perceived competence and attitudes towards patients with suicidal behaviour: a survey of general practitioners, psychiatrists and internists. BMC Health Serv Res. 2014, 14: 208-10.1186/1472-6963-14-208.CrossRefPubMedPubMedCentral Grimholt TK, Haavet OR, Jacobsen D, Sandvik L, Ekeberg L: Perceived competence and attitudes towards patients with suicidal behaviour: a survey of general practitioners, psychiatrists and internists. BMC Health Serv Res. 2014, 14: 208-10.1186/1472-6963-14-208.CrossRefPubMedPubMedCentral
49.
go back to reference Higgins JP, Altman DG, Gotzsche PC, Juni P, Moher D, Oxman AD, Savovic J, Schulz KF, Weeks L, Sterne JA: The Cochrane’s collaboration tool for assessing risk of bias in randomised trials. BMJ. 2011, 343: d5928-10.1136/bmj.d5928.CrossRefPubMedPubMedCentral Higgins JP, Altman DG, Gotzsche PC, Juni P, Moher D, Oxman AD, Savovic J, Schulz KF, Weeks L, Sterne JA: The Cochrane’s collaboration tool for assessing risk of bias in randomised trials. BMJ. 2011, 343: d5928-10.1136/bmj.d5928.CrossRefPubMedPubMedCentral
51.
go back to reference Atkins D, Best D, Briss PA, Eccles M, Falck-Ytter Y, Flottorp S, Guyatt GH, Harbour RT, Haugh MC, Henry D, Hill S, Jaeschke R, Leng G, Liberati A, Magrini N, Mason J, Middleton P, Mrukowicz J, O’Connell D, Oxman AD, Phillips B, Schunemann HJ, Edejer T, Varonen H, Vist GE, Williams JW, Zaza S, GRADE Working Group: Grading quality of evidence and strength of recommendations. BMJ. 2004, 328: 1490-CrossRefPubMed Atkins D, Best D, Briss PA, Eccles M, Falck-Ytter Y, Flottorp S, Guyatt GH, Harbour RT, Haugh MC, Henry D, Hill S, Jaeschke R, Leng G, Liberati A, Magrini N, Mason J, Middleton P, Mrukowicz J, O’Connell D, Oxman AD, Phillips B, Schunemann HJ, Edejer T, Varonen H, Vist GE, Williams JW, Zaza S, GRADE Working Group: Grading quality of evidence and strength of recommendations. BMJ. 2004, 328: 1490-CrossRefPubMed
Metadata
Title
Educational interventions for general practitioners to identify and manage depression as a suicide risk factor in young people: a systematic review and meta-analysis protocol
Authors
Lynda Tait
Maria Michail
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Systematic Reviews / Issue 1/2014
Electronic ISSN: 2046-4053
DOI
https://doi.org/10.1186/2046-4053-3-145

Other articles of this Issue 1/2014

Systematic Reviews 1/2014 Go to the issue