Published in:
01-12-2010 | Editorial
Editorial: The Imperative to Authenticate Cell Lines
Author:
John H. Healey, MD, FACS
Published in:
Clinical Orthopaedics and Related Research®
|
Issue 12/2010
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Excerpt
Contamination plagues cell culture research and requires our immediate attention. Cell culture is a powerful tool to investigate the mechanisms of disease, test new drug therapies, and potentially create and engineer tissues. In vitro culture facilitates cancer and stem cell research, in particular. These areas are of great interest to orthopaedic researchers and the subject of many publications in our translational and clinical research journal, Clinical Orthopaedics and Related Research. The integrity of our research and publication effort requires that results are accurate and reproducible. This means that contamination of cell lines must be recognized and eliminated. …