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Published in: JA Clinical Reports 1/2023

Open Access 01-12-2023 | ECMO | Case report

Venoarterial-extra corporeal membrane oxygenation-assisted parathyroidectomy for hypercalcemic crisis due to parathyroid carcinoma complicated by severe circulatory and respiratory failure: a case report

Authors: Yuria Enomoto, Yuko Matsuda, Yusuke Nagamine, Takahisa Goto

Published in: JA Clinical Reports | Issue 1/2023

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Abstract

Background

Hypercalcemia crisis is a rare but severe form of hypercalcemia complicated by multiple organ failure. Hypercalcemia crisis due to hyperparathyroidism is commonly caused by a parathyroid tumor, which often requires surgical resection. However, there are no clear recommendations on when the surgery should be performed.

Case presentation

A 64-year-old female patient developed hyperparathyroidism due to a parathyroid tumor and hypercalcemic crisis, which was complicated by severe circulatory and respiratory failure refractory to medical therapy, and an emergent surgery was planned to resect the parathyroid tumor. To prevent intraoperative circulatory and respiratory collapse, venoarterial-extra corporeal membrane oxygenation (VA-ECMO) was introduced, resulting in a safe operation and anesthetic management.

Conclusions

In patients with hypercalcemic crisis complicated by severe circulatory and respiratory failure, induction of prophylactic VA-ECMO was useful for safe anesthetic management. Surgical resection should be performed as soon as the diagnosis is made before VA-ECMO is required.
Literature
1.
go back to reference Ahmad S, Kuraganti G, Steenkamp D. Hypercalcemic crisis: a clinical review. Am J Med. 2015;128:239–45.CrossRefPubMed Ahmad S, Kuraganti G, Steenkamp D. Hypercalcemic crisis: a clinical review. Am J Med. 2015;128:239–45.CrossRefPubMed
2.
go back to reference Knoll K, Kurowski V, Schunkert H, Sager HB. Management of hypercalcaemia-induced heart failure using mechanical circulatory support. Eur J Cardiothorac Surg. 2018;54:784–5.CrossRefPubMed Knoll K, Kurowski V, Schunkert H, Sager HB. Management of hypercalcaemia-induced heart failure using mechanical circulatory support. Eur J Cardiothorac Surg. 2018;54:784–5.CrossRefPubMed
3.
go back to reference Gagnier JJ, Kienle G, Altman DG, et al. The CARE guidelines: consensus-based clinical case report guideline development. J Clin Epidemiol. 2014;67:46–51.CrossRefPubMed Gagnier JJ, Kienle G, Altman DG, et al. The CARE guidelines: consensus-based clinical case report guideline development. J Clin Epidemiol. 2014;67:46–51.CrossRefPubMed
4.
go back to reference Cannon J, Lew JI, Solorzano CC. Parathyroidectomy for hypercalcemic crisis: 40 years’ experience and long-term outcomes. Surgery. 2010;148:807–12 discussion 12–3.CrossRefPubMed Cannon J, Lew JI, Solorzano CC. Parathyroidectomy for hypercalcemic crisis: 40 years’ experience and long-term outcomes. Surgery. 2010;148:807–12 discussion 12–3.CrossRefPubMed
5.
go back to reference Phitayakorn R, McHenry CR. Hyperparathyroid crisis: use of bisphosphonates as a bridge to parathyroidectomy. J Am Coll Surg. 2008;206:1106–15.CrossRefPubMed Phitayakorn R, McHenry CR. Hyperparathyroid crisis: use of bisphosphonates as a bridge to parathyroidectomy. J Am Coll Surg. 2008;206:1106–15.CrossRefPubMed
6.
7.
go back to reference Ikegaki S, Otoshi T, Hirai T, Hirabayashi M. A rare case of parathyroid crisis with respiratory failure successfully treated using extracorporeal membrane oxygenation. Respir Med Case Rep. 2020;30: 101088.PubMedPubMedCentral Ikegaki S, Otoshi T, Hirai T, Hirabayashi M. A rare case of parathyroid crisis with respiratory failure successfully treated using extracorporeal membrane oxygenation. Respir Med Case Rep. 2020;30: 101088.PubMedPubMedCentral
9.
go back to reference Payne JE Jr, Tanenberg RJ. Hyperparathyroid crisis and acute necrotizing pancreatitis presenting as diabetic ketoacidosis. Am J Surg. 1980;140:698–703.CrossRefPubMed Payne JE Jr, Tanenberg RJ. Hyperparathyroid crisis and acute necrotizing pancreatitis presenting as diabetic ketoacidosis. Am J Surg. 1980;140:698–703.CrossRefPubMed
10.
11.
go back to reference Schmittinger CA, Dunser MW, Torgersen C, et al. Histologic pathologies of the myocardium in septic shock: a prospective observational study. Shock. 2013;39:329–35.CrossRefPubMed Schmittinger CA, Dunser MW, Torgersen C, et al. Histologic pathologies of the myocardium in septic shock: a prospective observational study. Shock. 2013;39:329–35.CrossRefPubMed
12.
go back to reference Koufakis T, Antonopoulou V, Grammatiki M, et al. The relationship between primary hyperparathyroidism and thrombotic events: report of three cases and a review of potential mechanisms. Int J Hematol Oncol Stem Cell Res. 2018;12:175–80.PubMedPubMedCentral Koufakis T, Antonopoulou V, Grammatiki M, et al. The relationship between primary hyperparathyroidism and thrombotic events: report of three cases and a review of potential mechanisms. Int J Hematol Oncol Stem Cell Res. 2018;12:175–80.PubMedPubMedCentral
13.
go back to reference Chen HI, Yeh DY, Kao SJ. The detrimental role of inducible nitric oxide synthase in the pulmonary edema caused by hypercalcemia in conscious rats and isolated lungs. J Biomed Sci. 2008;15:227–38.CrossRefPubMed Chen HI, Yeh DY, Kao SJ. The detrimental role of inducible nitric oxide synthase in the pulmonary edema caused by hypercalcemia in conscious rats and isolated lungs. J Biomed Sci. 2008;15:227–38.CrossRefPubMed
14.
go back to reference Lew JI, Solorzano CC, Irvin GL 3rd. Long-term results of parathyroidectomy for hypercalcemic crisis. Arch Surg. 2006;141:696–9 discussion 700.CrossRefPubMed Lew JI, Solorzano CC, Irvin GL 3rd. Long-term results of parathyroidectomy for hypercalcemic crisis. Arch Surg. 2006;141:696–9 discussion 700.CrossRefPubMed
Metadata
Title
Venoarterial-extra corporeal membrane oxygenation-assisted parathyroidectomy for hypercalcemic crisis due to parathyroid carcinoma complicated by severe circulatory and respiratory failure: a case report
Authors
Yuria Enomoto
Yuko Matsuda
Yusuke Nagamine
Takahisa Goto
Publication date
01-12-2023
Publisher
Springer Berlin Heidelberg
Published in
JA Clinical Reports / Issue 1/2023
Electronic ISSN: 2363-9024
DOI
https://doi.org/10.1186/s40981-023-00606-y

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