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Journal of Cardiothoracic Surgery

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Open Access 01-12-2023 | ECMO | Research

Extracorporeal membrane oxygenation in paediatric cardiac surgery: 5-year single centre experience

Authors: Laurynas Bezuska, Jonathan P. O’Doherty, Bilal Ali, Chris Harvey, Ikenna Omeje, Branko Mimic

Published in: Journal of Cardiothoracic Surgery | Issue 1/2023

Abstract

Background

Extracorporeal membrane oxygenation (ECMO) has become an integral part of paediatric cardiac surgery. We report the experience of a well-established ECMO service over 5 years.

Methods

This retrospective study analysed all paediatric patients who required ECMO support following cardiac surgery from April 2015 to March 2020. Inclusion criteria were age less than 18 years and post-operative ECMO support. Patients were analysed dividing into groups according to the urgency for ECMO support (extracorporeal cardiopulmonary resuscitation (ECPR) and cardiac ECMO) and according to age (neonatal and paediatric ECMO groups). They were followed for 30-day, 6-month mortality, long-term survival, postoperative morbidity and the need for reintervention.

Results

Forty-six patients were included who had a total of venoarterial (VA) 8 ECMO runs. The 5-year incidence of the need for VA ECMO after cardiac surgery was 3.3% (48 of the overall 1441 cases recorded). The median follow-up period was 3.5 (interquartile ranges, 0.8–4.7) years. Thirty-day, 6-month and follow-up survival rate was 85%, 65% and 52% respectively. At the 6-month follow-up, the ECPR group showed a trend towards worse survival compared with the cardiac ECMO group (47% vs. 55%) but with no statistical significance (p = 0.35). Furthermore, the survival rates between paediatric (60%) and neonatal (46%) ECMO groups were similar, with no statistical significance (p = 0.45). The rate of acute neurological events was 27% (13/48).

Conclusion

ECPR and neonatal ECMO groups had higher mortality. VA ECMO 30-day and 6-month survival rates were 85% and 65% respectively. Major neurological injury resulting in ECMO termination occurred in 3 patients. Accumulated experiences and protocols in ECMO management can improve mortality and morbidity.

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Title: Extracorporeal membrane oxygenation in paediatric cardiac surgery: 5-year single centre experience
Authors: Laurynas Bezuska
Jonathan P. O’Doherty
Bilal Ali
Chris Harvey
Ikenna Omeje
Branko Mimic
Publication date: 01-12-2023
Publisher: BioMed Central
Keywords: ECMO
ECMO
Pediatric Cardiac Surgery
Published in: Journal of Cardiothoracic Surgery / Issue 1/2023
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/s13019-023-02440-w

2024 ASCO Annual Meeting

Springer Medicine

Extracorporeal membrane oxygenation in paediatric cardiac surgery: 5-year single centre experience

Abstract

Background

Methods

Results

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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