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Open Access 04-06-2022 | Echocardiography | Review

Expert proposal to characterize cardiac diseases with normal or preserved left ventricular ejection fraction and symptoms of heart failure by comprehensive echocardiography

Authors: A. Hagendorff, A. Helfen, R. Brandt, E. Altiok, O. Breithardt, D. Haghi, J. Knierim, D. Lavall, N. Merke, C. Sinning, S. Stöbe, C. Tschöpe, F. Knebel, S. Ewen

Published in: Clinical Research in Cardiology | Issue 1/2023

Abstract

Currently, the term “heart failure with preserved left ventricular ejection fraction (HFpEF)” is based on echocardiographic parameters and clinical symptoms combined with elevated or normal levels of natriuretic peptides. Thus, “HFpEF” as a diagnosis subsumes multiple pathophysiological entities making a uniform management plan for “HFpEF” impossible. Therefore, a more specific characterization of the underlying cardiac pathologies in patients with preserved ejection fraction and symptoms of heart failure is mandatory. The present proposal seeks to offer practical support by a standardized echocardiographic workflow to characterize specific diagnostic entities associated with “HFpEF”. It focuses on morphological and functional cardiac phenotypes characterized by echocardiography in patients with normal or preserved left ventricular ejection fraction (LVEF). The proposal discusses methodological issues to clarify why and when echocardiography is helpful to improve the diagnosis. Thus, the proposal addresses a systematic echocardiographic approach using a feasible algorithm with weighting criteria for interpretation of echocardiographic parameters related to patients with preserved ejection fraction and symptoms of heart failure. The authors consciously do not use the diagnosis “HFpEF” to avoid misunderstandings.

Graphical abstract

Central illustration: Scheme illustrating the characteristic echocardiographic phenotypes and their combinations in patients with “HFpEF” symptoms with respect to the respective cardiac pathology and pathophysiology as well as the underlying typical disease

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Title: Expert proposal to characterize cardiac diseases with normal or preserved left ventricular ejection fraction and symptoms of heart failure by comprehensive echocardiography
Authors: A. Hagendorff
A. Helfen
R. Brandt
E. Altiok
O. Breithardt
D. Haghi
J. Knierim
D. Lavall
N. Merke
C. Sinning
S. Stöbe
C. Tschöpe
F. Knebel
S. Ewen
Publication date: 04-06-2022
Publisher: Springer Berlin Heidelberg
Keywords: Echocardiography
Heart Failure
Echocardiography
Published in: Clinical Research in Cardiology / Issue 1/2023
Print ISSN: 1861-0684
Electronic ISSN: 1861-0692
DOI: https://doi.org/10.1007/s00392-022-02041-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Expert proposal to characterize cardiac diseases with normal or preserved left ventricular ejection fraction and symptoms of heart failure by comprehensive echocardiography

Abstract

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Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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The SGLT2 inhibitor empagliflozin reduces tissue sodium content in patients with chronic heart failure: results from a placebo-controlled randomised trial

Comorbidities complicating heart failure: changes over the last 15 years

Heart failure-related quality-of-life impairment after myocardial infarction

Nighttime hemodynamic phenotype. A novel risk factor for cardiovascular disease, especially heart failure: the practitioner-based nationwide JAMP study